Pharmacology Illustrated Reviews 7th Edition Whalen Test Bank
TABLE OF CONTENT
Chapter 1: Pharmacokinetics
Chapter 2: Drug–Receptor Interactions and Pharmacodynamics
Chapter 3: The Autonomic Nervous System
Chapter 4: Cholinergic Agonists
Chapter 5: Cholinergic Antagonists
Chapter 6: Adrenergic Agonists
Chapter 7: Adrenergic Antagonists
Chapter 8: Drugs for Neurodegenerative Diseases
Chapter 9: Anxiolytic and Hypnotic Drugs
Chapter 10: Antidepressants
Chapter 11: Antipsychotic Drugs
Chapter 12: Drugs for Epilepsy
Chapter 13: Anesthetics
Chapter 14: Opioids
Chapter 15: Drugs of Abuse
Chapter 16: CNS Stimulants
Chapter 17: Antihypertensives
Chapter 18: Diuretics
Chapter 19: Heart Failure
Chapter 20: Antiarrhythmics
Chapter 21: Antianginal Drugs
Chapter 22: Anticoagulants and Antiplatelet Agents
Chapter 23: Drugs for Hyperlipidemia
Chapter 24: Pituitary and Thyroid
Chapter 25: Drugs for Diabetes
Chapter 26: Estrogens and Androgens
Chapter 27: Adrenal Hormones
Chapter 28: Drugs for Obesity
Chapter 29: Drugs for Disorders of the Respiratory System
Chapter 30: Antihistamines
Chapter 31: Gastrointestinal and Antiemetic Drugs
Chapter 32: Drugs for Urologic Disorders
Chapter 33: Drugs for Anemia
Chapter 34: Drugs for Dermatologic Disorders
Chapter 35: Drugs for Bone Disorders
Chapter 36: Anti-inflammatory, Antipyretic, and Analgesic Agents
Chapter 37: Principles of Antimicrobial Therapy
Chapter 38: Cell Wall Inhibitors
Chapter 39: Protein Synthesis Inhibitors
Chapter 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics
Chapter 41: Antimycobacterial Drugs
Chapter 42: Antifungal Drugs
Chapter 43: Antiprotozoal Drugs
Chapter 44: Anthelmintic Drugs
Chapter 45: Antiviral Drugs
Chapter 46: Anticancer Drugs
Chapter 47: Immunosuppressants
Chapter 48: Clinical Toxicology
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3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
coated tablet. Which statement by the patient indicates understanding of the teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action.
ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of actions
after taking these medications. Enteric-coated tablets should not be crushed or chewed, which
would alter the time and location of absorption. Acidic foods will not enhance the absorption of
the medication. The patient should not to eat high-fat food before ingesting an enteric-coated
tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
given by subcutaneous injection instead of by mouth. The nurse will explain that this is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects.
ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 2 of 507
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5. The nurse is preparing to administer an oral medication that is water-soluble. The nurse
understands that this drug
a. must be taken on an empty stomach.
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal tract.
ANS: B
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
6. A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment.
How will the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food
ANS: C
Food can stimulate the production of gastric acid so medications requiring an acidic environment
should be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
7. The nurse is preparing an injectable drug and wants to administer it for rapid absorption. How
will the nurse give this medication?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper arm
ANS: A
Page 3 of 507
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TABLE OF CONTENT
Chapter 1: Pharmacokinetics
Chapter 2: Drug–Receptor Interactions and Pharmacodynamics
Chapter 3: The Autonomic Nervous System
Chapter 4: Cholinergic Agonists
Chapter 5: Cholinergic Antagonists
Chapter 6: Adrenergic Agonists
Chapter 7: Adrenergic Antagonists
Chapter 8: Drugs for Neurodegenerative Diseases
Chapter 9: Anxiolytic and Hypnotic Drugs
Chapter 10: Antidepressants
Chapter 11: Antipsychotic Drugs
Chapter 12: Drugs for Epilepsy
Chapter 13: Anesthetics
Chapter 14: Opioids
Chapter 15: Drugs of Abuse
Chapter 16: CNS Stimulants
Chapter 17: Antihypertensives
Chapter 18: Diuretics
Chapter 19: Heart Failure
Chapter 20: Antiarrhythmics
Chapter 21: Antianginal Drugs
Chapter 22: Anticoagulants and Antiplatelet Agents
Chapter 23: Drugs for Hyperlipidemia
Chapter 24: Pituitary and Thyroid
Chapter 25: Drugs for Diabetes
Chapter 26: Estrogens and Androgens
Chapter 27: Adrenal Hormones
Chapter 28: Drugs for Obesity
Chapter 29: Drugs for Disorders of the Respiratory System
Chapter 30: Antihistamines
Chapter 31: Gastrointestinal and Antiemetic Drugs
Chapter 32: Drugs for Urologic Disorders
Chapter 33: Drugs for Anemia
Chapter 34: Drugs for Dermatologic Disorders
Chapter 35: Drugs for Bone Disorders
Chapter 36: Anti-inflammatory, Antipyretic, and Analgesic Agents
Chapter 37: Principles of Antimicrobial Therapy
Chapter 38: Cell Wall Inhibitors
Chapter 39: Protein Synthesis Inhibitors
Chapter 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics
Chapter 41: Antimycobacterial Drugs
Chapter 42: Antifungal Drugs
Chapter 43: Antiprotozoal Drugs
Chapter 44: Anthelmintic Drugs
Chapter 45: Antiviral Drugs
Chapter 46: Anticancer Drugs
Chapter 47: Immunosuppressants
Chapter 48: Clinical Toxicology
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3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
coated tablet. Which statement by the patient indicates understanding of the teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action.
ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of actions
after taking these medications. Enteric-coated tablets should not be crushed or chewed, which
would alter the time and location of absorption. Acidic foods will not enhance the absorption of
the medication. The patient should not to eat high-fat food before ingesting an enteric-coated
tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
given by subcutaneous injection instead of by mouth. The nurse will explain that this is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects.
ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 2 of 507
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5. The nurse is preparing to administer an oral medication that is water-soluble. The nurse
understands that this drug
a. must be taken on an empty stomach.
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal tract.
ANS: B
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
6. A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment.
How will the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food
ANS: C
Food can stimulate the production of gastric acid so medications requiring an acidic environment
should be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
7. The nurse is preparing an injectable drug and wants to administer it for rapid absorption. How
will the nurse give this medication?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper arm
ANS: A
Page 3 of 507
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