Abrams' Clinical Drug Therapy:
v v v v
Rationales for Nursing Practice
v v v
12th EditionFrandsen Test
v v v v v
Bank v
,Chapterv 1v Thev Foundationv ofv Pharmacology:v Qualityv andv Safety
Avwomanvhasvbeenvprescribedvparoxetinevhyd
rochloride,vwhichvisvanvantidepressantvagentva
dministeredvinvpillvform.vThevmedicationvisvad
1.
ministeredvforvhervobsessive-
vcompulsivevdisorder.vThisvmedicationvwill
producevwhichvofv thevfollowingveffects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugsvthatvproducevsystemicveffectsvarevtakenvi
ntovthevbody,vcirculatedvthroughvthevbloodstrea
mvtovtheirvsitesvofvactionvinvvariousvbodyvtissues
,vandveventuallyveliminatedvfromvthevbody.vCura
tivevagentsvarevgivenvtovcurevavdiseasevprocess.vI
nvthisvcase,vparoxetinevhydrochloridevwillvcontr
olvthevsymptomsvbutvnotvcurevthevdisorder.vDrug
svwithvlocalveffects,vsuchvasvsunscreenvandvlocalv
anesthetics,vactvmainlyvatvthevsitevofvapplication.
vParoxetinevhydrochloridevisvnotvadministeredv
parenterally.vParenteralvagentsvarev administere
dvsubcutaneously,vintramuscularly,
orvintravenously.
Avpatientvhasvbeenvprescribedvanvantibiotic.vT
hisvmedicationvisvavnaturallyvoccurringvsubsta
2. ncevthatvhasvbeenvchemicallyvmodified.vWhatvi
svanothervnamevforvthisvtypevof
medication?
A) Syntheticvdrug
B) Semisyntheticv drug
C) Biotechnologyv drug
D) Prototypev drug
Ans: B
Feedback:
Semisyntheticvdrugsv(e.g.,vmanyvantibiotics)v ar
evnaturallyvoccurringvsubstancesvthatvhavevbeen
vchemicallyvmodified.vSyntheticvdrugsvarevmor
evstandardizedvinvtheirvchemicalvcharacteristics
,vmorevconsistentvinvtheirv effects,vandvlessvlike
lyvtovproducevallergicvreactions.vBiotechnology
vdrugsvinvolvevmanipulatingvDNAvandvRNAvan
dv recombiningvgenesvintovhybridvmoleculesvth
atvcanvbevinsertedvintovlivingvorganisms.
, Avpatientvhasvbeenvprescribedvanvantibiotic.vT
hisvmedicationvisvavnaturallyvoccurring
2.
Whatvisvanothervnamevforvthisvtypevofvmedica
tion?
Syntheticv drug
subSsetamnicseynththatethicasdbrueegn v v chemicallyv v modified.
BiotechnologyvdrugvPrototyp
A) evdrug
B
B)
Feedback:
C)
D) arevnaturallyvoccurringv substancesvthatv have
Ans:
morevstandardizedvinvtheirvchemicalvSem chisayr
n th e t ic d r u g s ( e .g . , vmany antibiot cs)
acteristics,vm o r e c onsistent in their
effects,vandvlessvlikelyvtovproducevallergicvbeerneacchteiomnisc.aBlliy
otmecohdnifoileodg.ySdyrnuthgestincvdorluvgesv are
manipulatingv DNAv andvRNAv and
canvbevinsertedvintovlivingvorganisms.v
Prototypevdrugsvarevthevfirstvdrugvofvav
particularvgroupvtovbevdeveloped.
recombiningv genesvintov hybridv moleculesv that
3. differentvways.v Whichv ofvthevfollowing
classificationsvappliesvtovmorphine?
Av pCaetinetnratvlisneardvmoiunsisstyesrteedmmdoerpprheisnsea.nMtv v orphine
isvaCpernottroatlynpeicrvaolvudsrusgysttheam tvcsatnimbuelacnlatssifiedvinv
Anti-inflammatory
A) Antihypertensivev
B) A
Feedback:
C)
D)
Ans: uses,vandvtheirvchemicalvcharacteristics.vForvexampl
e,vmorphinevcanvbevclassifiedvasva
Drucgensvtarraelvnclearsvsoifuisedsyasctceomrddienpgretosstahnetiranefdfeacts
onvparticularvbodyvsystems,vtheirv therapeutic
systemvstimulantvincreasesvattentionvandvr
aisesvmood.vAnvanti-inflammatoryvagent
narcoticvorvopioidvanalgesic.vAvcentralvnervousvreduce
svbloodvpressure.
decreasesvinflammationvatvthevsitevofvtissuevorvj
oinAtv ipnaftliaem
ntmisataiodnm.iA
ninsteanretidhaym
peorxteicnislilvinev agent
4. (Amoxil).vThevgenericvnamevofv this
drugv group?
Selectivev serotoninv reuptakev inhibitors
D i u r e ti cs
me di c a t io n indicates v thatv itv belongsv tov whichvAC
Penicillins
A) Evinhibitors
B) C
C) Feedback:
D) Thevgenericvnamevoftenvindicatesvthevdrug
Ans:
groaunpti(de.pgr.,esdsraungtsew ffiethctsg;eS neSrRicIvnisamavbesroeandding
vinv“
cclailslsinif”icarteiopne,nnicoitllaingse)n.veSreiclenctaim
vve.seDrioutroentincs
v are medicationsv th at incr eas e urin e o u t p u t;
reuptakev inhibit r a re m edi cati ons th atv ha v e
enzymevinhibitors,vnotvthev genericvname. name.vACEvinhibitorvisvthevbroad
diureticvisvavbroadvclassification,vnotvavgeneric
, Avpatientvisvadministeredvamoxicillinv(Amoxil
).vThevgenericvnamevofvthisvmedicationvindicat
4.
esvthatvitvbelongsvtovwhich
drugv group?
A) Selectivevserotoninv reuptakevinhibitors
B) Diuretics
C) Penicillins
D) ACEvinhibitors
Ans: C
Feedback:
Thevgenericvnamevoftenvindicatesvthevdrugvgro
upv(e.g.,vdrugsvwithvgenericvnamesvendingvinv“
cillin”varevpenicillins).vSelectivevserotoninvreu
ptakevinhibitorsvarevmedicationsvthatvhavevanti
depressantveffects;vSSRIvisvavbroadvclassificati
on,vnotvavgenericvname.vDiureticsvarevmedicati
onsvthatvincreasevurinevoutput;vdiureticvisvavbro
advclassification,vnotvavgenericvname.vACEvinh
ibitorvisvthevbroadv classificationvforvthevangiot
ensin-converting
enzymevinhibitors,vnotvthev genericvname.
Thevadministrationvofvdiphenhydraminev(Benadr
yl),vwhichvisvanvover-the-
5.
countervmedication,visvregulatedvbyvwhichvgover
nment
agency?
A) PublicvHealthv Service
B) FederalvTradev Commission
OccupationalvSafetyvandv Health
C)
Administration
D) Foodvandv Drugv Administration
Ans: D
Feedback:
ThevFoodvandvDrugvAdministrationvapprovesv
drugsvforvover-the-
countervavailability,vincludingvthevtransfervofv
drugsvfromvprescriptionvtovOTCvstatus,vandvm
ayvrequirevclinicalvtrialsvtovdeterminevthevsafet
yvandveffectivenessvofvOTCvuse.vThevPublicvH
ealthvServicevisvregulatedvbyvthevstatevtovmaint
ainvthevhealthvofvindividualvcitizensvofvthevstat
e.vThevFederalvTradevCommissionvregulatesvi
mportsvandvexportsvthroughoutvthevnation.
ThevOccupationalvSafetyv andv Health
Administrationvregulatesvsafetyvwithinvthevwo
rkplace.
Thevadministrationv ofvanabolicvsteroidsvis
6.
regulatedvbyvwhichvofvthevfollowingvlaws?
A) ThevFood,vDrug,vandv CosmeticvActvofv1938
Thev Comprehensivev Drugv Abusev Prevention
B)
andvControlvAct
C) ThevHarrisonv Narcoticv Act
D) ThevShirleyv Amendment
Ans: B
Feedback:
v v v v
Rationales for Nursing Practice
v v v
12th EditionFrandsen Test
v v v v v
Bank v
,Chapterv 1v Thev Foundationv ofv Pharmacology:v Qualityv andv Safety
Avwomanvhasvbeenvprescribedvparoxetinevhyd
rochloride,vwhichvisvanvantidepressantvagentva
dministeredvinvpillvform.vThevmedicationvisvad
1.
ministeredvforvhervobsessive-
vcompulsivevdisorder.vThisvmedicationvwill
producevwhichvofv thevfollowingveffects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugsvthatvproducevsystemicveffectsvarevtakenvi
ntovthevbody,vcirculatedvthroughvthevbloodstrea
mvtovtheirvsitesvofvactionvinvvariousvbodyvtissues
,vandveventuallyveliminatedvfromvthevbody.vCura
tivevagentsvarevgivenvtovcurevavdiseasevprocess.vI
nvthisvcase,vparoxetinevhydrochloridevwillvcontr
olvthevsymptomsvbutvnotvcurevthevdisorder.vDrug
svwithvlocalveffects,vsuchvasvsunscreenvandvlocalv
anesthetics,vactvmainlyvatvthevsitevofvapplication.
vParoxetinevhydrochloridevisvnotvadministeredv
parenterally.vParenteralvagentsvarev administere
dvsubcutaneously,vintramuscularly,
orvintravenously.
Avpatientvhasvbeenvprescribedvanvantibiotic.vT
hisvmedicationvisvavnaturallyvoccurringvsubsta
2. ncevthatvhasvbeenvchemicallyvmodified.vWhatvi
svanothervnamevforvthisvtypevof
medication?
A) Syntheticvdrug
B) Semisyntheticv drug
C) Biotechnologyv drug
D) Prototypev drug
Ans: B
Feedback:
Semisyntheticvdrugsv(e.g.,vmanyvantibiotics)v ar
evnaturallyvoccurringvsubstancesvthatvhavevbeen
vchemicallyvmodified.vSyntheticvdrugsvarevmor
evstandardizedvinvtheirvchemicalvcharacteristics
,vmorevconsistentvinvtheirv effects,vandvlessvlike
lyvtovproducevallergicvreactions.vBiotechnology
vdrugsvinvolvevmanipulatingvDNAvandvRNAvan
dv recombiningvgenesvintovhybridvmoleculesvth
atvcanvbevinsertedvintovlivingvorganisms.
, Avpatientvhasvbeenvprescribedvanvantibiotic.vT
hisvmedicationvisvavnaturallyvoccurring
2.
Whatvisvanothervnamevforvthisvtypevofvmedica
tion?
Syntheticv drug
subSsetamnicseynththatethicasdbrueegn v v chemicallyv v modified.
BiotechnologyvdrugvPrototyp
A) evdrug
B
B)
Feedback:
C)
D) arevnaturallyvoccurringv substancesvthatv have
Ans:
morevstandardizedvinvtheirvchemicalvSem chisayr
n th e t ic d r u g s ( e .g . , vmany antibiot cs)
acteristics,vm o r e c onsistent in their
effects,vandvlessvlikelyvtovproducevallergicvbeerneacchteiomnisc.aBlliy
otmecohdnifoileodg.ySdyrnuthgestincvdorluvgesv are
manipulatingv DNAv andvRNAv and
canvbevinsertedvintovlivingvorganisms.v
Prototypevdrugsvarevthevfirstvdrugvofvav
particularvgroupvtovbevdeveloped.
recombiningv genesvintov hybridv moleculesv that
3. differentvways.v Whichv ofvthevfollowing
classificationsvappliesvtovmorphine?
Av pCaetinetnratvlisneardvmoiunsisstyesrteedmmdoerpprheisnsea.nMtv v orphine
isvaCpernottroatlynpeicrvaolvudsrusgysttheam tvcsatnimbuelacnlatssifiedvinv
Anti-inflammatory
A) Antihypertensivev
B) A
Feedback:
C)
D)
Ans: uses,vandvtheirvchemicalvcharacteristics.vForvexampl
e,vmorphinevcanvbevclassifiedvasva
Drucgensvtarraelvnclearsvsoifuisedsyasctceomrddienpgretosstahnetiranefdfeacts
onvparticularvbodyvsystems,vtheirv therapeutic
systemvstimulantvincreasesvattentionvandvr
aisesvmood.vAnvanti-inflammatoryvagent
narcoticvorvopioidvanalgesic.vAvcentralvnervousvreduce
svbloodvpressure.
decreasesvinflammationvatvthevsitevofvtissuevorvj
oinAtv ipnaftliaem
ntmisataiodnm.iA
ninsteanretidhaym
peorxteicnislilvinev agent
4. (Amoxil).vThevgenericvnamevofv this
drugv group?
Selectivev serotoninv reuptakev inhibitors
D i u r e ti cs
me di c a t io n indicates v thatv itv belongsv tov whichvAC
Penicillins
A) Evinhibitors
B) C
C) Feedback:
D) Thevgenericvnamevoftenvindicatesvthevdrug
Ans:
groaunpti(de.pgr.,esdsraungtsew ffiethctsg;eS neSrRicIvnisamavbesroeandding
vinv“
cclailslsinif”icarteiopne,nnicoitllaingse)n.veSreiclenctaim
vve.seDrioutroentincs
v are medicationsv th at incr eas e urin e o u t p u t;
reuptakev inhibit r a re m edi cati ons th atv ha v e
enzymevinhibitors,vnotvthev genericvname. name.vACEvinhibitorvisvthevbroad
diureticvisvavbroadvclassification,vnotvavgeneric
, Avpatientvisvadministeredvamoxicillinv(Amoxil
).vThevgenericvnamevofvthisvmedicationvindicat
4.
esvthatvitvbelongsvtovwhich
drugv group?
A) Selectivevserotoninv reuptakevinhibitors
B) Diuretics
C) Penicillins
D) ACEvinhibitors
Ans: C
Feedback:
Thevgenericvnamevoftenvindicatesvthevdrugvgro
upv(e.g.,vdrugsvwithvgenericvnamesvendingvinv“
cillin”varevpenicillins).vSelectivevserotoninvreu
ptakevinhibitorsvarevmedicationsvthatvhavevanti
depressantveffects;vSSRIvisvavbroadvclassificati
on,vnotvavgenericvname.vDiureticsvarevmedicati
onsvthatvincreasevurinevoutput;vdiureticvisvavbro
advclassification,vnotvavgenericvname.vACEvinh
ibitorvisvthevbroadv classificationvforvthevangiot
ensin-converting
enzymevinhibitors,vnotvthev genericvname.
Thevadministrationvofvdiphenhydraminev(Benadr
yl),vwhichvisvanvover-the-
5.
countervmedication,visvregulatedvbyvwhichvgover
nment
agency?
A) PublicvHealthv Service
B) FederalvTradev Commission
OccupationalvSafetyvandv Health
C)
Administration
D) Foodvandv Drugv Administration
Ans: D
Feedback:
ThevFoodvandvDrugvAdministrationvapprovesv
drugsvforvover-the-
countervavailability,vincludingvthevtransfervofv
drugsvfromvprescriptionvtovOTCvstatus,vandvm
ayvrequirevclinicalvtrialsvtovdeterminevthevsafet
yvandveffectivenessvofvOTCvuse.vThevPublicvH
ealthvServicevisvregulatedvbyvthevstatevtovmaint
ainvthevhealthvofvindividualvcitizensvofvthevstat
e.vThevFederalvTradevCommissionvregulatesvi
mportsvandvexportsvthroughoutvthevnation.
ThevOccupationalvSafetyv andv Health
Administrationvregulatesvsafetyvwithinvthevwo
rkplace.
Thevadministrationv ofvanabolicvsteroidsvis
6.
regulatedvbyvwhichvofvthevfollowingvlaws?
A) ThevFood,vDrug,vandv CosmeticvActvofv1938
Thev Comprehensivev Drugv Abusev Prevention
B)
andvControlvAct
C) ThevHarrisonv Narcoticv Act
D) ThevShirleyv Amendment
Ans: B
Feedback:
