Test Bank fo
d d
r
Lehninger Principles of Biochemistry
d d d
Fourth Edition
d
TERRY PLATT EU
d d
GENE BARBER
d
W.dH.dFreemandanddCompany
NewdYork
,ISBN:d0-7167-5952-7
EAN:d9780716759522
©d2005dbydW.dH.dFreemandanddCompanyd
Alldrightsdreserved.
PrinteddindthedUniteddStatesdofdAmericadFi
rstdprinting
W.dH.dFreemandanddCompanyd4
1dMadisondAvenue
NewdYork,dNYd10010
Houndmills,dBasingstokedR621d6XS,dEnglanddwww.whfreeman.co
m
, Contents
Chapterd1:dFoundationsdofdBiochemistry,d1
Chapterd2:dWater,d12
Chapterd3:dAminodAcids,dPeptides,danddProteins,d21d Chapter
4:dThedThree-
d
DimensionaldStructuredofdProteins,d38dChapterd5:dProteindFu
nction,d51
Chapterd6:dEnzymes,d60
Chapterd7:dCarbohydratesdanddGlycobiology,d80dChapte
rd8:dNucleotidesdanddNucleicdAcids,d89
Chapterd9:dDNA-BaseddInformationdTechnologies,d101
Chapterd10:dLipids,d110
Chapterd11:dBiologicaldMembranesdanddTransport,d118d
Chapterd12:dBiosignaling,d133
Chapterd13:dPrinciplesdofdBioenergetics,d145
Chapterd14:dGlycolysis,dGluconeogenesis,danddthedPentosedPhosphatedPathway,d157dChapter
d 15:dPrinciplesdofdMetabolicdRegulation,d176
Chapterd16:dThedCitricdAciddCycle,d185dC
hapterd17:dFattydAciddCatabolism
Chapterd18:dAminodAciddOxidationdanddthedProductiondofdUrea,d210dChapt
erd19:dOxidativedPhosphorylationdanddPhotophosphorylation,d220dChapterd
20:dCarbohydratedBiosynthesisdindPlantsdanddBacteria,d238dChapterd21:dLi
piddBiosynthesis,d248
Chapterd22:dBiosynthesisdofdAminodAcids,dNucleotides,danddRelateddMolecules,d259dChapte
rd23:dIntegrationdanddHormonaldRegulationdofdMammaliandMetabolism,d272dChapterd24:dGe
nesdanddChromosomes,d280
Chapterd25:dDNAdMetabolism,d289
Chapterd26:dRNAdMetabolism,d301
Chapterd27:dProteindMetabolism,d313
Chapterd28:dRegulationdofdGenedExpression,d326
, Preface
Thisdcollectiondofdoverd1400dmultiple-choicedanddshort-
answerdtestdquestionsdanddsolutionsdisdintendeddfordusedwithdNelsondanddCox:dLehningerdPrinciplesd
ofdBiochemistry,dFourthdEdition,dindadfirstdbiochemistrydcoursedfordupper-
divisiondundergraduatesdordfordbeginningdgraduatedordmedicaldstudents.d Moredthand25%dofdthedques
tionsdarednewdordreviseddfordthisdedition.
Asdindpriordeditions,deachdchapterdofdthisdTestdBankdhasdtwodsetsdofdquestions—
multipledchoicedanddshortdanswer—
whichdaredsequentiallydnumbereddanddwhichdreflectdthedtopicaldorganizationdofdthedtext.d Eachdquest
iondisdtieddtodthedmostdrelevantdsectiondheadingdofdthedchapterdthatditdtests,dwithdtextdpagednumberdre
ferencesdtodassistdindyourdexamdpreparation.d Theddifficultydgradationsdare:d1dfordeasy,d2dfordmoderat
e,dandd3dfordchallenging.d Thedlatterdrequiredeitherdthedsynthesisdofdseveraldconceptsdordideasdtodsolv
edadcomplexdproblemdordmoredtimedtodanswerdthandadquestiondofdaverageddifficulty.
Althoughdmanydofdthedmultipledchoicedquestionsdrequiredonlydthedknowledgedofdseveraldcha
racteristicdfacts,dsomeddemanddthinkingdthroughdadqualitativedproblem,dapplyingdandimportantdequat
ion,dordperformingdquantitativedcalculations.dMostdofdthedshortdanswerdquestionsdrequiredworkingdw
ithdordexplainingdandimportantdbiochemicaldprinciple,dapplieddtodadspecificdsituation.dWheredpossibl
e,dthedanswersdwilldprovidedadreferencedtodadspecificdpagedordfiguredindthedtextbook.
AdcomputerizeddversiondofdthedTestdBankdisdavailabledondthedInstructor’sdResourcedCD-
dROM.dItdisdorganizeddbydchapterdasdbothd.pdfdanddWorddfiles,dwhichdcandbedcopieddtodadhardddrived
orduploadeddtodadnetworkdserver.d ThedWorddfilesdcandbedediteddanddinserteddintodyourdowndexamsda
nddquizzes.d FordmoredinformationdondthedcomputerizeddTestdBankdanddthedInstructor’sdResourcedC
D-ROM,dcontactdW.dH.dFreemandanddCompanydPublishers.
ThedTestdBankdfordthedThirddEditiondprovideddandessentialdframeworkdfordourdrevisions,dan
ddmanydofdthedquestionsdaredfactuallydunchanged,dbutdwedhavedmadedseveraldimportantdpedagogical
dalterationsdtodimprovedtheirdusefulness.dFirst,danswersdtodthedmultipledchoiced questionsdarednowdlis
teddindalphabeticaldorderdtodavoiddguessingdbydlocation,danddhavedbeendrephraseddindmanydinstances
dtodavoiddguessingdbydstructuredordsize.d Second,dwedhavedincludeddfivedoptionsdfordmultipledchoiced
answersdwhereverdfeasible.dThird,dindlinedwithdcurrentdtest-
writingdideals,dwedhavedeliminated,dordchangeddwheredpossible,dquestionsdinvolvingdconfusingddou
blednegatives,dordchoicesdofdthed“Alldaredtrue,dexcept”dstyle,dasdwelldasd“Alld(ordnone)dofdthedabove”dt
ypesdanddvariationsdondthesedthemes.d Alldnewdquestionsdalsodadheredtodthisdstandard.
WedhavedrelieddheavilydondthedpreviousdeditiondofdthedTestdBank,dwithdthanksdtodRhondadSc
ott-Ennisd(UniversitydofdWisconsin–
RiverdFalls),dRogerdPerselld(HunterdCollege),danddRickdAmasinodanddMikedCoxd(UniversitydofdWis
consin–
Madison),dwhodalldcontributeddtodseveraldofdthosedchapters;danddGeralddFrenkeld(RutgersdUniversit
y),dwhodcontributeddgreatlydtodthedThirddEditiondversion.d WedalsodthankdMelaniedMaysdanddNickdT
ymoczkodatdW.dH.dFreemandanddCompanydPublishersdfordtheirdeffortsdindcoordinatingdthisdproject.d
Finally,dwedareddeeplydgratefuldtodStephaniedScovilledatdRochesterdfordherdcheerful,dtireless,danddout
standingdeffortsdindpreparingdthedcamera-readydcopy—wedtrulydcoulddnotdhaveddoneditdwithoutdher.
IfdindusingdthisdTestdBankdyouddiscoverdambiguitiesdorderrors,dordcandofferdanydsuggestionsd
fordimprovement,dwedwoulddverydmuchdappreciatedhearingdfromdyou.d Indparticular,difdyoudhavedany
dfavoritedquestionsdordproblemsdfromdyourdowndexperiencedthatdyoudmightdlikedtodseedincludeddindth
ednextdeditiondofdthedTestdBank,dwedwoulddbeddelighteddtodconsiderdthem!d Pleasedsenddanydquestion
.
TerrydPlatt
dEugenedBarbe
r
d d
r
Lehninger Principles of Biochemistry
d d d
Fourth Edition
d
TERRY PLATT EU
d d
GENE BARBER
d
W.dH.dFreemandanddCompany
NewdYork
,ISBN:d0-7167-5952-7
EAN:d9780716759522
©d2005dbydW.dH.dFreemandanddCompanyd
Alldrightsdreserved.
PrinteddindthedUniteddStatesdofdAmericadFi
rstdprinting
W.dH.dFreemandanddCompanyd4
1dMadisondAvenue
NewdYork,dNYd10010
Houndmills,dBasingstokedR621d6XS,dEnglanddwww.whfreeman.co
m
, Contents
Chapterd1:dFoundationsdofdBiochemistry,d1
Chapterd2:dWater,d12
Chapterd3:dAminodAcids,dPeptides,danddProteins,d21d Chapter
4:dThedThree-
d
DimensionaldStructuredofdProteins,d38dChapterd5:dProteindFu
nction,d51
Chapterd6:dEnzymes,d60
Chapterd7:dCarbohydratesdanddGlycobiology,d80dChapte
rd8:dNucleotidesdanddNucleicdAcids,d89
Chapterd9:dDNA-BaseddInformationdTechnologies,d101
Chapterd10:dLipids,d110
Chapterd11:dBiologicaldMembranesdanddTransport,d118d
Chapterd12:dBiosignaling,d133
Chapterd13:dPrinciplesdofdBioenergetics,d145
Chapterd14:dGlycolysis,dGluconeogenesis,danddthedPentosedPhosphatedPathway,d157dChapter
d 15:dPrinciplesdofdMetabolicdRegulation,d176
Chapterd16:dThedCitricdAciddCycle,d185dC
hapterd17:dFattydAciddCatabolism
Chapterd18:dAminodAciddOxidationdanddthedProductiondofdUrea,d210dChapt
erd19:dOxidativedPhosphorylationdanddPhotophosphorylation,d220dChapterd
20:dCarbohydratedBiosynthesisdindPlantsdanddBacteria,d238dChapterd21:dLi
piddBiosynthesis,d248
Chapterd22:dBiosynthesisdofdAminodAcids,dNucleotides,danddRelateddMolecules,d259dChapte
rd23:dIntegrationdanddHormonaldRegulationdofdMammaliandMetabolism,d272dChapterd24:dGe
nesdanddChromosomes,d280
Chapterd25:dDNAdMetabolism,d289
Chapterd26:dRNAdMetabolism,d301
Chapterd27:dProteindMetabolism,d313
Chapterd28:dRegulationdofdGenedExpression,d326
, Preface
Thisdcollectiondofdoverd1400dmultiple-choicedanddshort-
answerdtestdquestionsdanddsolutionsdisdintendeddfordusedwithdNelsondanddCox:dLehningerdPrinciplesd
ofdBiochemistry,dFourthdEdition,dindadfirstdbiochemistrydcoursedfordupper-
divisiondundergraduatesdordfordbeginningdgraduatedordmedicaldstudents.d Moredthand25%dofdthedques
tionsdarednewdordreviseddfordthisdedition.
Asdindpriordeditions,deachdchapterdofdthisdTestdBankdhasdtwodsetsdofdquestions—
multipledchoicedanddshortdanswer—
whichdaredsequentiallydnumbereddanddwhichdreflectdthedtopicaldorganizationdofdthedtext.d Eachdquest
iondisdtieddtodthedmostdrelevantdsectiondheadingdofdthedchapterdthatditdtests,dwithdtextdpagednumberdre
ferencesdtodassistdindyourdexamdpreparation.d Theddifficultydgradationsdare:d1dfordeasy,d2dfordmoderat
e,dandd3dfordchallenging.d Thedlatterdrequiredeitherdthedsynthesisdofdseveraldconceptsdordideasdtodsolv
edadcomplexdproblemdordmoredtimedtodanswerdthandadquestiondofdaverageddifficulty.
Althoughdmanydofdthedmultipledchoicedquestionsdrequiredonlydthedknowledgedofdseveraldcha
racteristicdfacts,dsomeddemanddthinkingdthroughdadqualitativedproblem,dapplyingdandimportantdequat
ion,dordperformingdquantitativedcalculations.dMostdofdthedshortdanswerdquestionsdrequiredworkingdw
ithdordexplainingdandimportantdbiochemicaldprinciple,dapplieddtodadspecificdsituation.dWheredpossibl
e,dthedanswersdwilldprovidedadreferencedtodadspecificdpagedordfiguredindthedtextbook.
AdcomputerizeddversiondofdthedTestdBankdisdavailabledondthedInstructor’sdResourcedCD-
dROM.dItdisdorganizeddbydchapterdasdbothd.pdfdanddWorddfiles,dwhichdcandbedcopieddtodadhardddrived
orduploadeddtodadnetworkdserver.d ThedWorddfilesdcandbedediteddanddinserteddintodyourdowndexamsda
nddquizzes.d FordmoredinformationdondthedcomputerizeddTestdBankdanddthedInstructor’sdResourcedC
D-ROM,dcontactdW.dH.dFreemandanddCompanydPublishers.
ThedTestdBankdfordthedThirddEditiondprovideddandessentialdframeworkdfordourdrevisions,dan
ddmanydofdthedquestionsdaredfactuallydunchanged,dbutdwedhavedmadedseveraldimportantdpedagogical
dalterationsdtodimprovedtheirdusefulness.dFirst,danswersdtodthedmultipledchoiced questionsdarednowdlis
teddindalphabeticaldorderdtodavoiddguessingdbydlocation,danddhavedbeendrephraseddindmanydinstances
dtodavoiddguessingdbydstructuredordsize.d Second,dwedhavedincludeddfivedoptionsdfordmultipledchoiced
answersdwhereverdfeasible.dThird,dindlinedwithdcurrentdtest-
writingdideals,dwedhavedeliminated,dordchangeddwheredpossible,dquestionsdinvolvingdconfusingddou
blednegatives,dordchoicesdofdthed“Alldaredtrue,dexcept”dstyle,dasdwelldasd“Alld(ordnone)dofdthedabove”dt
ypesdanddvariationsdondthesedthemes.d Alldnewdquestionsdalsodadheredtodthisdstandard.
WedhavedrelieddheavilydondthedpreviousdeditiondofdthedTestdBank,dwithdthanksdtodRhondadSc
ott-Ennisd(UniversitydofdWisconsin–
RiverdFalls),dRogerdPerselld(HunterdCollege),danddRickdAmasinodanddMikedCoxd(UniversitydofdWis
consin–
Madison),dwhodalldcontributeddtodseveraldofdthosedchapters;danddGeralddFrenkeld(RutgersdUniversit
y),dwhodcontributeddgreatlydtodthedThirddEditiondversion.d WedalsodthankdMelaniedMaysdanddNickdT
ymoczkodatdW.dH.dFreemandanddCompanydPublishersdfordtheirdeffortsdindcoordinatingdthisdproject.d
Finally,dwedareddeeplydgratefuldtodStephaniedScovilledatdRochesterdfordherdcheerful,dtireless,danddout
standingdeffortsdindpreparingdthedcamera-readydcopy—wedtrulydcoulddnotdhaveddoneditdwithoutdher.
IfdindusingdthisdTestdBankdyouddiscoverdambiguitiesdorderrors,dordcandofferdanydsuggestionsd
fordimprovement,dwedwoulddverydmuchdappreciatedhearingdfromdyou.d Indparticular,difdyoudhavedany
dfavoritedquestionsdordproblemsdfromdyourdowndexperiencedthatdyoudmightdlikedtodseedincludeddindth
ednextdeditiondofdthedTestdBank,dwedwoulddbeddelighteddtodconsiderdthem!d Pleasedsenddanydquestion
.
TerrydPlatt
dEugenedBarbe
r
