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CLINICOPATHOLOGIC FOUNDATIONS d d
OF MEDICINE 7TH EDITION 2023 HIGH G
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1. Ischemiadanddotherdtoxicdinjuriesdincreasedthedaccumulationdofdintracellulardcalciumdasdadresultdof
:
A) releasedofdstoreddcalciumdfromdthedmitochondria.
B) improveddintracellulardvolumedregulation.
C) decreaseddinfluxdacrossdthedcelldmembrane.
D) attractiondofdcalciumdtodfattydinfiltrates.
2. Thedpatientdisdfounddtodhavedliverddisease,dresultingdindthedremovaldofdadlobedofdhisdliver.dAdaptati
ondtodthedreduceddsizedofdthedliverdleadsdtod_ ofdthedremainingdliverdcells.
A) metaplasia
B) organdatrophy
C) compensatorydhyperplasia
D) physiologicdhypertrophy
Adpersondeatingdpeanutsdstartsdchokingdanddcollapses.dHisdairwaydobstructiondisdpartiallydcl
eared,dbutdhedremainsdhypoxicduntildhedreachesdthedhospital.dThedprolongeddcelldhypoxiadca
3. useddadcerebraldinfarctiondanddresulting _dindthedbrain.
A) caspasedactivation
B) coagulationdnecrosis
C) rapiddphagocytosis
D) proteindp53ddeficiency
4. Bacteriad andd virusesd caused celld damaged byd ,d whichd isd uniqued fromd thed intracellulard damagedc
auseddbydotherdinjuriousdagents.
, A) disruptingdthedsodium/potassiumdATPasedpump
B) interruptingdoxidativedmetabolismdprocesses
Chapterd1:dCelldAdaptation,dInjurydanddDeath
C) replicatingdanddproducingdcontinueddinjury
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INICOPATHOLOGIC FOUNDATIONS OF d d d
MEDICINE 7TH EDITION ( WITH ANSWER
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KEY)
5. Thedpatientdhasdadprolongeddinterruptiondindarterialdblooddflowdtodhisdleftdkidney,dcausingdhypoxicd
celldinjurydanddthedreleasedofdfreedradicals.dFreedradicalsddamagedcellsdby:
A) destroyingdphospholipidsdindthedcelldmembrane.
B) alteringdthedimmunedresponsedofdthedcell.
C) disruptingdcalciumdstoragedindthedcell.
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D) decreasingdproteindsynthesisdanddfunction
D) inactivationdofdenzymesdanddmitochondria.
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d d d
GUIDE 2023 d
,TEST BANK FOR RUBIN’S PATHOLOGY:
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CLINICOPATHOLOGIC FOUNDATIONS d
OF
MEDICINE 7TH EDITION ( WITH ANSWER KEY
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)
6. Injureddcellsdhavedimpaireddflowdofdsubstancesdthroughdthedcelldmembranedasdadresultdof:
A) increaseddfatdload.
B) altereddpermeability.
C) altereddglucosedutilization.
D) increaseddsurfacedreceptors.
7. Reversibledadaptivedintracellulardresponsesdaredinitiateddby:
A) stimulusdoverload.
B) geneticdmutations.
C) chemicaldmessengers.
D) mitochondrialdDNA.
8. Injureddcellsdbecomedverydswollendasdadresultdof:
A) increaseddcelldproteindsynthesis.
B) altereddcelldvolumedregulation.
C) passivedentrydofdpotassiumdintodthedcell.
D) blebdformationdindthedplasmadmembrane.
Addiabeticdpatientdhasdimpaireddsensation,dcirculation,danddoxygenationdofdhisdfeet.dHedstepsdonda
dpiecedofdglass,dthedwoundddoesdnotdheal,danddthedareadtissuedbecomesdnecrotic.dThednecroticdcelld
9. deathdisdcharacterizeddby:
A) rapiddapoptosis.
B) cellulardrupture.
C) shrinkagedanddcollapse.
D) chronicdinflammation.
10. Ad99-year-
olddwomandhasdexperienceddtheddeclinedofdcelldfunctiondassociateddwithdage.dAdgroupdofdtheorie
, sdofdcellulardagingdfocusdondprogrammed:
A) changesdwithdgeneticdinfluences.
B) eliminationdofdcelldreceptordsites.
C) insufficientdtelomerasedenzyme.
GUARANTEED GRADE A+ d d