Workman & LaCharity: Understanding Pharmacology: Essentials for Me
r r r r r r r
dication Safety, 2nd Edition Complete Testbank ( Chapter 1-
r r
r
r r r r r
32 ) with Explained Answers
r r r r
Chapterr01:rDrugrRegulation,rActions,randrResponsesrMUL
TIPLErCHOICE
BASICrCONCEPTS
1. Whichrhealthrcarerprofessionalrhasrthermajorrresponsibilityrforrdispensingrprescribedrdr
ugsrunderrtherdirectionrofrarpharmacist?
a. Physician
b Nurserpractitioner
.
c. Licensedrnurse
d Pharmacyrtechnician
.
ANS:r D
Therphysicianrandrnurserpractitionerrhaverthermajorrresponsibilityrforrprescribingrdrugs,rnotrdispen
singrthem.rTherlicensedrnurserhasrtherprimaryrresponsibilityrforradministeringrdrugs,ralthoughrunde
rrsomercircumstancesrarlicensedrnursermayrdispenserprescribedrdrugsrbutrthisrisrnotrhisrorrherrmajorrr
esponsibilityrinrdrugrtherapy.rTherpharmacyrtechnicianrhasrthermajorrresponsibilityrofrdispensingrp
rescribedrdrugsrunderrtherdirectionrofrarlicensedrpharmacist.
DIF: CognitiverLevel:rRemembering REF: p.r3
2. Whichrtermrdescribesrthereffectrofrardrugrthatrimprovesrbodyrfunction?
a. Sidereffect
b Intendedraction
.
c. Adverserreaction
d Idiosyncraticrresponse
.
ANS:r B
Therpurposerofrdrugrtherapyrisrtortakerardrugrtorprevent,rreduce,rorrcorrectrarhealthrproblem.rThisrres
ponserisranyrdrug’srintendedractionralsorknownrasrartherapeuticrresponse.
DIF: CognitiverLevel:rRemembering REF: p.r3
3. Whichrtyperofrdrugrnamerisr“owned”rbyrthercompanyrthatr manufacturesrit?
a. Genericrname
b Chemicalrname
, .
c. Categoryrname
d Tradername
.
ANS:r D
Therchemicalrnamerisrardrug’srexactrchemicalrcomposition.rThergenericrnamerisrthernamerassignedr
tortherdrugrbyrtherU.S.rAdoptedrNamesrCouncilrandrisrnotrownedrbyranyone.rThercategoryrnamerref
ersrtorthertyperofrdrugr(whatritrdoesrorrwhatritrisrusedrfor)randrisrnotranractualrdrugrname.rThertraderna
mer(brandrname)risrthernamerprovidedrandrownedrbyrarspecificrdrug’srmanufacturer.
DIF: CognitiverLevel:rRemembering REF: p.r4
4. Whichrdrugrorrdrugrclassrisrar“highralert”rdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:r B
Arhighralertrdrugrisronerinrwhichrharmrisrlikelyrtorresultrifrgivenratrtherwrongrdose,rtortherwrongrpatien
t,rorrnotrgivenrtorthercorrectrpatient.rDrugsrclassifiedrasrhighralertrdrugsrincluderpotassium,rnarcoticsr(
opioids),rinsulin,rcancerrchemotherapyrdrugs,randrheparinr(orranyrdrugrthatrstronglyraffectsrbloodrcl
otting).rPenicillin,rNSAIDs,randrcalciumrarernotrconsideredrhighralertrdrugs.
DIF: CognitiverLevel:rRemembering REF: p.r4
5. Whatrisrthertermrforrardrugrthatrhasrthersameractionrasrarnaturallyroccurringrbodyrhor
monerorrenzyme?
a. Agonist
b Blockingragent
.
c. Chemical
d Duplicator
.
ANS:r r A
Ardrugragonistrisranrextrinsicrdrugrthatractivatesrtherreceptorrsitesrofrarcellrandrmimicsrtheractionsrofr
naturallyroccurringr bodyrsubstancesr(intrinsicrdrugs).rArblockingragentr isrardrug
,antagonist.rArchemicalrwouldrnotrnecessarilyrberardrugratrall.rArduplicatorrisrnotrarpharmacologicrterm.
DIF: CognitiverLevel:rRemembering REF: pp.r 6-7
6. Whichrtermrdescribesrhowrtherbodyraffectsrdrugractivity?
a. Drugrpotency
b Pharmacodynamics
.
c. Therapeuticreffect
d Pharmacokinetics
.
ANS:r D
Thertermrpharmacokineticsrrefersrtordrugrmetabolismrandrhowrtherbodyrchangesrardrug.rPharmaco
dynamicsrrefersrtorhowrardrugrworksrtorchangerbodyrfunction.rDrugrpotencyrrefersrtorhowrstronglyro
rrtorwhatrdegreerardrugrexertsritsreffects.rThertherapeuticreffectrisrcloserrtorpharmacodynamics,rmea
ningrhowrardrugrworksrtorchangerbodyrfunction.
DIF: CognitiverLevel:rRemembering REF: p.r10
7. InrtherUnitedrStates,rwhichrgrouprisrresponsiblerforrenforcingrestablishedrstandardsrforrdru
grmanufacturing?
a. U.S.rPharmacopeia
b NationalrInstitutesrofrHealth
.
c. FoodrandrDrugrAdministration
d AssociationrofrPharmaceuticalrManufacturers
.
ANS:r C
TherstandardsrforrdrugrmanufacturerarerestablishedrbyrtherU.S.rPharmacopeia.rTheserstandardsrarer
enforcedrbyrtherFoodrandrDrugrAdministration.rNeitherrtherNationalrInstitutesrofrHealthrnorrtherAss
ociationrofrPharmaceuticalrManufacturersrhasranyrauthorityrtorenforcerdrugrstandards.
DIF: CognitiverLevel:rRemembering REF: p.r5
8. Whichrfactorrisrarmajorrdisadvantagerofrthertransdermalrdrugrdeliveryrroute?
a. Onlyrarprescriberr canradministerrdrugsrbyrthertransdermalrroute.
b Transdermalrdrugsrmustrbersterilerratherrthanrclean.
.
c. Firstrpassrdrugrlossrbyrthisrrouterisrthermostr extensive.
d Drugrabsorptionrisrdependentronradequatercirculation.
, .
ANS:r D
Oncerartransdermalrdrugrmovesrthroughrtherskin,ritrmustrenterrtherbloodstreamrtorreachritsrtargetrtissu
e.rIfrcirculationrisrpoorrtortherarearwhererthertransdermalrdrugrisrapplied,rveryrlittle,rifrany,rofrtherdrugr
willrreachritsrtargetrtissue.
DIF: CognitiverLevel:rRemembering REF: p.r12
9. Howrarerintrinsicrdrugsrdifferentr fromrextrinsicrdrugs?
a.Intrinsicrdrugsrarermaderbyrtherbody,rwhereasrextrinsicrdrugsrarermaderoutsidertherbody.
b Intrinsicrdrugsrareradministeredrbyrtherparenteralrroute,rwhereasrextrinsicrdrugsrareradministere
. drbyrtheroralrroute.
c.Extrinsicrdrugsrcanronlyrberappliedrtortherskinrorrmucousrmembranes,rwhereasrintrinsic
drugsrarertakenrinternally.
d Extrinsicrdrugsrrequirerarprescriptionrforradministration,rwhereasrintrinsicrdrugsrareravailabler
. over-the-counter.
ANS:r r A
Intrinsicrdrugsrarertherhormones,renzymes,randrotherrchemicalsrmaderbyrtherbodyrthatrchangercellra
ctivity.rExtrinsicrdrugsrarermanufacturedrfromrchemical,ranimal,rorrplantrsourcesrandrmustrhaverarm
eansrofrenteringrtherbodyrinrorderrtorchangercellractivity.
DIF: CognitiverLevel:rUnderstanding REF: p.r3
10. Arpatientrasksrwhyrhisrdrugrtorcontrolrhighrbloodrpressurerhasronlyronergenericrnamerandrtwor
differentrtradernames.rWhatrisryourrbestrresponse?
a. “Mostrdrugsrhaverdifferentrtradernamesrthatrindicaterdifferentrdosages.”
b “Thertwordifferentrtradernamesrindicaterthatronerisrarmorerpurerandrsaferrdrugrthanrthe
. other.”
c. “Thergenericrnamerisrtheractualrofficialrdrugrnamerandrthertradernamerisrarbrandrownedrbyrarspe
cificrmanufacturer.”
d “Ifryourhaverinsurance,ryourcanrgetrthertradernamerdrug,rwhichrisrusuallyrmorerexpensiverthanrth
. ergenericrnamedrdrug.”
ANS:r C
ThergenericrnamerisrthernamerassignedrtortherdrugrbyrtherU.S.rAdoptedrNamesrCouncilrandrisrnotrow
nedrbyranyone.rThertradernamer(brandrname)risrthernamerprovidedrandrownedrbyrarspecificrdrug’srm
anufacturer.rMorerthanronermanufacturerrcanrmakerandrsellrthersamerdrugratrthersamertimerunderrardif
ferentrtradername.rRegardlessrofrtradername,rallrdrugsrthatrhaverthersamergenericrnamermustrberaliker
inrtheirrchemicalrcompositionrandrstrength.
DIF: CognitiverLevel:rApplyingrorrHigher REF: pp.r 3-4
r r r r r r r
dication Safety, 2nd Edition Complete Testbank ( Chapter 1-
r r
r
r r r r r
32 ) with Explained Answers
r r r r
Chapterr01:rDrugrRegulation,rActions,randrResponsesrMUL
TIPLErCHOICE
BASICrCONCEPTS
1. Whichrhealthrcarerprofessionalrhasrthermajorrresponsibilityrforrdispensingrprescribedrdr
ugsrunderrtherdirectionrofrarpharmacist?
a. Physician
b Nurserpractitioner
.
c. Licensedrnurse
d Pharmacyrtechnician
.
ANS:r D
Therphysicianrandrnurserpractitionerrhaverthermajorrresponsibilityrforrprescribingrdrugs,rnotrdispen
singrthem.rTherlicensedrnurserhasrtherprimaryrresponsibilityrforradministeringrdrugs,ralthoughrunde
rrsomercircumstancesrarlicensedrnursermayrdispenserprescribedrdrugsrbutrthisrisrnotrhisrorrherrmajorrr
esponsibilityrinrdrugrtherapy.rTherpharmacyrtechnicianrhasrthermajorrresponsibilityrofrdispensingrp
rescribedrdrugsrunderrtherdirectionrofrarlicensedrpharmacist.
DIF: CognitiverLevel:rRemembering REF: p.r3
2. Whichrtermrdescribesrthereffectrofrardrugrthatrimprovesrbodyrfunction?
a. Sidereffect
b Intendedraction
.
c. Adverserreaction
d Idiosyncraticrresponse
.
ANS:r B
Therpurposerofrdrugrtherapyrisrtortakerardrugrtorprevent,rreduce,rorrcorrectrarhealthrproblem.rThisrres
ponserisranyrdrug’srintendedractionralsorknownrasrartherapeuticrresponse.
DIF: CognitiverLevel:rRemembering REF: p.r3
3. Whichrtyperofrdrugrnamerisr“owned”rbyrthercompanyrthatr manufacturesrit?
a. Genericrname
b Chemicalrname
, .
c. Categoryrname
d Tradername
.
ANS:r D
Therchemicalrnamerisrardrug’srexactrchemicalrcomposition.rThergenericrnamerisrthernamerassignedr
tortherdrugrbyrtherU.S.rAdoptedrNamesrCouncilrandrisrnotrownedrbyranyone.rThercategoryrnamerref
ersrtorthertyperofrdrugr(whatritrdoesrorrwhatritrisrusedrfor)randrisrnotranractualrdrugrname.rThertraderna
mer(brandrname)risrthernamerprovidedrandrownedrbyrarspecificrdrug’srmanufacturer.
DIF: CognitiverLevel:rRemembering REF: p.r4
4. Whichrdrugrorrdrugrclassrisrar“highralert”rdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:r B
Arhighralertrdrugrisronerinrwhichrharmrisrlikelyrtorresultrifrgivenratrtherwrongrdose,rtortherwrongrpatien
t,rorrnotrgivenrtorthercorrectrpatient.rDrugsrclassifiedrasrhighralertrdrugsrincluderpotassium,rnarcoticsr(
opioids),rinsulin,rcancerrchemotherapyrdrugs,randrheparinr(orranyrdrugrthatrstronglyraffectsrbloodrcl
otting).rPenicillin,rNSAIDs,randrcalciumrarernotrconsideredrhighralertrdrugs.
DIF: CognitiverLevel:rRemembering REF: p.r4
5. Whatrisrthertermrforrardrugrthatrhasrthersameractionrasrarnaturallyroccurringrbodyrhor
monerorrenzyme?
a. Agonist
b Blockingragent
.
c. Chemical
d Duplicator
.
ANS:r r A
Ardrugragonistrisranrextrinsicrdrugrthatractivatesrtherreceptorrsitesrofrarcellrandrmimicsrtheractionsrofr
naturallyroccurringr bodyrsubstancesr(intrinsicrdrugs).rArblockingragentr isrardrug
,antagonist.rArchemicalrwouldrnotrnecessarilyrberardrugratrall.rArduplicatorrisrnotrarpharmacologicrterm.
DIF: CognitiverLevel:rRemembering REF: pp.r 6-7
6. Whichrtermrdescribesrhowrtherbodyraffectsrdrugractivity?
a. Drugrpotency
b Pharmacodynamics
.
c. Therapeuticreffect
d Pharmacokinetics
.
ANS:r D
Thertermrpharmacokineticsrrefersrtordrugrmetabolismrandrhowrtherbodyrchangesrardrug.rPharmaco
dynamicsrrefersrtorhowrardrugrworksrtorchangerbodyrfunction.rDrugrpotencyrrefersrtorhowrstronglyro
rrtorwhatrdegreerardrugrexertsritsreffects.rThertherapeuticreffectrisrcloserrtorpharmacodynamics,rmea
ningrhowrardrugrworksrtorchangerbodyrfunction.
DIF: CognitiverLevel:rRemembering REF: p.r10
7. InrtherUnitedrStates,rwhichrgrouprisrresponsiblerforrenforcingrestablishedrstandardsrforrdru
grmanufacturing?
a. U.S.rPharmacopeia
b NationalrInstitutesrofrHealth
.
c. FoodrandrDrugrAdministration
d AssociationrofrPharmaceuticalrManufacturers
.
ANS:r C
TherstandardsrforrdrugrmanufacturerarerestablishedrbyrtherU.S.rPharmacopeia.rTheserstandardsrarer
enforcedrbyrtherFoodrandrDrugrAdministration.rNeitherrtherNationalrInstitutesrofrHealthrnorrtherAss
ociationrofrPharmaceuticalrManufacturersrhasranyrauthorityrtorenforcerdrugrstandards.
DIF: CognitiverLevel:rRemembering REF: p.r5
8. Whichrfactorrisrarmajorrdisadvantagerofrthertransdermalrdrugrdeliveryrroute?
a. Onlyrarprescriberr canradministerrdrugsrbyrthertransdermalrroute.
b Transdermalrdrugsrmustrbersterilerratherrthanrclean.
.
c. Firstrpassrdrugrlossrbyrthisrrouterisrthermostr extensive.
d Drugrabsorptionrisrdependentronradequatercirculation.
, .
ANS:r D
Oncerartransdermalrdrugrmovesrthroughrtherskin,ritrmustrenterrtherbloodstreamrtorreachritsrtargetrtissu
e.rIfrcirculationrisrpoorrtortherarearwhererthertransdermalrdrugrisrapplied,rveryrlittle,rifrany,rofrtherdrugr
willrreachritsrtargetrtissue.
DIF: CognitiverLevel:rRemembering REF: p.r12
9. Howrarerintrinsicrdrugsrdifferentr fromrextrinsicrdrugs?
a.Intrinsicrdrugsrarermaderbyrtherbody,rwhereasrextrinsicrdrugsrarermaderoutsidertherbody.
b Intrinsicrdrugsrareradministeredrbyrtherparenteralrroute,rwhereasrextrinsicrdrugsrareradministere
. drbyrtheroralrroute.
c.Extrinsicrdrugsrcanronlyrberappliedrtortherskinrorrmucousrmembranes,rwhereasrintrinsic
drugsrarertakenrinternally.
d Extrinsicrdrugsrrequirerarprescriptionrforradministration,rwhereasrintrinsicrdrugsrareravailabler
. over-the-counter.
ANS:r r A
Intrinsicrdrugsrarertherhormones,renzymes,randrotherrchemicalsrmaderbyrtherbodyrthatrchangercellra
ctivity.rExtrinsicrdrugsrarermanufacturedrfromrchemical,ranimal,rorrplantrsourcesrandrmustrhaverarm
eansrofrenteringrtherbodyrinrorderrtorchangercellractivity.
DIF: CognitiverLevel:rUnderstanding REF: p.r3
10. Arpatientrasksrwhyrhisrdrugrtorcontrolrhighrbloodrpressurerhasronlyronergenericrnamerandrtwor
differentrtradernames.rWhatrisryourrbestrresponse?
a. “Mostrdrugsrhaverdifferentrtradernamesrthatrindicaterdifferentrdosages.”
b “Thertwordifferentrtradernamesrindicaterthatronerisrarmorerpurerandrsaferrdrugrthanrthe
. other.”
c. “Thergenericrnamerisrtheractualrofficialrdrugrnamerandrthertradernamerisrarbrandrownedrbyrarspe
cificrmanufacturer.”
d “Ifryourhaverinsurance,ryourcanrgetrthertradernamerdrug,rwhichrisrusuallyrmorerexpensiverthanrth
. ergenericrnamedrdrug.”
ANS:r C
ThergenericrnamerisrthernamerassignedrtortherdrugrbyrtherU.S.rAdoptedrNamesrCouncilrandrisrnotrow
nedrbyranyone.rThertradernamer(brandrname)risrthernamerprovidedrandrownedrbyrarspecificrdrug’srm
anufacturer.rMorerthanronermanufacturerrcanrmakerandrsellrthersamerdrugratrthersamertimerunderrardif
ferentrtradername.rRegardlessrofrtradername,rallrdrugsrthatrhaverthersamergenericrnamermustrberaliker
inrtheirrchemicalrcompositionrandrstrength.
DIF: CognitiverLevel:rApplyingrorrHigher REF: pp.r 3-4
