,Glycolysa starting CHzOH
Enzyme/Catalyst ·
Input Output Intermediate
CHzOPOS
1) 8
hexokinase No
po po poHo po 8
H
H It H
8 It OH 8 It OH
H OH
H OH H OH
Glucose ATD ADP (G6P)
Glucose-6-Phosphate
CH2OPOS3 -pro
2) It 8
i
·
Glucose Phosphate N/A N/A
-
!
Chay CH20l
H OH Isomerase Cisomerization) H
H OH
Glucose-6-Phosphate (G6P)
fructose-6-Phosphate (F64)
Pozn
upo
3) !
Chry CH20
PFK-I No
po po poHo po
6 Che
O
Ou
H 8 It OH 8 It OH
Hpo -
,
fructose-6-Phosphate (F64) ATD ADP fructose-1 6-bisphosphate (F1GBP)
,
Pozn
0
4)
CH ,OPOzz-
↓
Chay Oh
Aldolase N/A N/A c H-0
-
seavage)
Ho-k I
fructose-1 6-bisphosphate (F1GBP)
,
Dihydroxyaceture Phosphate (DHAP] Glyceraldehyde
3 -
Phosphate(GART
5) % CHOPOS
trose Phosphate N/A N/A H-0
Ho-k Isomerase llsomerization) I
Dihydroxyaceture Phosphate (DHAP) Glyceraldehyde 3-Phosphate (GAPY
+
6)H0 3-P NAD + NADH H 84 0poy"
glyavaldehyde
+ -
I dehydrogenase (G3PDH) (practice structure) H-c
Glyceraldehyde 3-Phosphate (GAPY 3- Bisphosphoglycerate (1 3-BPG)
1, ,
7)or a oa po po oa °
0-
-
phosphoglycerate kinase po
·
Ho
8H OH 8 It OH H-c
1,
3- Bisphosphoglycerate (1 3-BPG) ADP ATD
5-Phosphoglycerate (34G)
,
°
0-
8) °
- 0-
-
Phosphoglycerate nutase N/A N/A
H-c Crarangement
H-POST
5-Phosphoglycerate (34G) 2-Phosphoglycert (2PG)
9)
-
80
Enolase N/A N/A C
(dehydration) Dops t
2-Phosphoglycert (2PG) PhosphoenolPyrak (PEP)
&
10) %10-
pro po na po po oa
C
Pyruvate
Ho Ho
Kinase
Dops t
ADP
8H OH 8 It OH
PhosphoenolPyrak (PEP) ATD
Pyruvate
, Step s Input
Enzyme/Catalyst Output Intermediate
Starting
1)
Coo
-
Slot Citrate
Synthase none
2 coo none
0 :
altz
k 0 =
+
Ha -
coo
o - 2-coo-
CHz It cltz
coo-
Acetyl CoA + oxaloacetate
Citrate
Coo H
-
2) altz Aconitase none none # 0 -
C
I
-
coo-
-2 coo
-
C
-
Ho
(isoncrase) H COO
-
- -
cltz
coo- H 2 -
100-
,
Citrate Isocitrate
H
3) 100
-
C coo- +
# 0
NAD NADH H
-
Isocitrati
-
+ +
I
C
Cltz
dehydrogenase
-
GUz
H
- -
COO
H
,
2 -
100-
It
-
Isocitrate
-Ketoglutarate
4) X-Retoglutarate
200- NADr NADI + If t
-
200
altz
dehydrogenase CO2
It it
- s-cot
-Ketoglutarate Succinyl cot
topoppi
-
200
-
COO
P
5) altz cat iltz
Sainyl
it synthase aor
-
a
i CHtz
coo-
GDP Pi
s-cot
+
cot Succinate
Succinyl
Coo
-
-
COO
6 Succinate FAD FADHz cit
iltz
- denydrogenase 200
+
Succinate Funrate
91 10 -
Coo
-
,
7) cit funcrase HyW none Ho - Ch
+
200 cltz
Funrate
-
-
Malath
91 10 -
8
,
Ch malate NAD NADH H
+ C
-
+ + 0 =
-
100
Ho -
cltz It a coo-
dehydrogenase
-
,
-
-
Malath Ovoaloacetate
Enzyme/Catalyst ·
Input Output Intermediate
CHzOPOS
1) 8
hexokinase No
po po poHo po 8
H
H It H
8 It OH 8 It OH
H OH
H OH H OH
Glucose ATD ADP (G6P)
Glucose-6-Phosphate
CH2OPOS3 -pro
2) It 8
i
·
Glucose Phosphate N/A N/A
-
!
Chay CH20l
H OH Isomerase Cisomerization) H
H OH
Glucose-6-Phosphate (G6P)
fructose-6-Phosphate (F64)
Pozn
upo
3) !
Chry CH20
PFK-I No
po po poHo po
6 Che
O
Ou
H 8 It OH 8 It OH
Hpo -
,
fructose-6-Phosphate (F64) ATD ADP fructose-1 6-bisphosphate (F1GBP)
,
Pozn
0
4)
CH ,OPOzz-
↓
Chay Oh
Aldolase N/A N/A c H-0
-
seavage)
Ho-k I
fructose-1 6-bisphosphate (F1GBP)
,
Dihydroxyaceture Phosphate (DHAP] Glyceraldehyde
3 -
Phosphate(GART
5) % CHOPOS
trose Phosphate N/A N/A H-0
Ho-k Isomerase llsomerization) I
Dihydroxyaceture Phosphate (DHAP) Glyceraldehyde 3-Phosphate (GAPY
+
6)H0 3-P NAD + NADH H 84 0poy"
glyavaldehyde
+ -
I dehydrogenase (G3PDH) (practice structure) H-c
Glyceraldehyde 3-Phosphate (GAPY 3- Bisphosphoglycerate (1 3-BPG)
1, ,
7)or a oa po po oa °
0-
-
phosphoglycerate kinase po
·
Ho
8H OH 8 It OH H-c
1,
3- Bisphosphoglycerate (1 3-BPG) ADP ATD
5-Phosphoglycerate (34G)
,
°
0-
8) °
- 0-
-
Phosphoglycerate nutase N/A N/A
H-c Crarangement
H-POST
5-Phosphoglycerate (34G) 2-Phosphoglycert (2PG)
9)
-
80
Enolase N/A N/A C
(dehydration) Dops t
2-Phosphoglycert (2PG) PhosphoenolPyrak (PEP)
&
10) %10-
pro po na po po oa
C
Pyruvate
Ho Ho
Kinase
Dops t
ADP
8H OH 8 It OH
PhosphoenolPyrak (PEP) ATD
Pyruvate
, Step s Input
Enzyme/Catalyst Output Intermediate
Starting
1)
Coo
-
Slot Citrate
Synthase none
2 coo none
0 :
altz
k 0 =
+
Ha -
coo
o - 2-coo-
CHz It cltz
coo-
Acetyl CoA + oxaloacetate
Citrate
Coo H
-
2) altz Aconitase none none # 0 -
C
I
-
coo-
-2 coo
-
C
-
Ho
(isoncrase) H COO
-
- -
cltz
coo- H 2 -
100-
,
Citrate Isocitrate
H
3) 100
-
C coo- +
# 0
NAD NADH H
-
Isocitrati
-
+ +
I
C
Cltz
dehydrogenase
-
GUz
H
- -
COO
H
,
2 -
100-
It
-
Isocitrate
-Ketoglutarate
4) X-Retoglutarate
200- NADr NADI + If t
-
200
altz
dehydrogenase CO2
It it
- s-cot
-Ketoglutarate Succinyl cot
topoppi
-
200
-
COO
P
5) altz cat iltz
Sainyl
it synthase aor
-
a
i CHtz
coo-
GDP Pi
s-cot
+
cot Succinate
Succinyl
Coo
-
-
COO
6 Succinate FAD FADHz cit
iltz
- denydrogenase 200
+
Succinate Funrate
91 10 -
Coo
-
,
7) cit funcrase HyW none Ho - Ch
+
200 cltz
Funrate
-
-
Malath
91 10 -
8
,
Ch malate NAD NADH H
+ C
-
+ + 0 =
-
100
Ho -
cltz It a coo-
dehydrogenase
-
,
-
-
Malath Ovoaloacetate
