Tuesday 16 May 2023 – Morning
GCSE (9–1) Combined Science (Biology) A
(Gateway Science)
J250/01 Paper 1 (Foundation Tier)
Time allowed: 1 hour 10 minutes
F
*9132068913*
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 5 0 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
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, 2
Section A
You should spend a maximum of 20 minutes on this section.
Write your answer to each question in the box provided.
1 Which of these substances is transported out of the human body as waste?
A Blood
B Food molecules
C Oxygen
D Urea
Your answer [1]
2 The graph shows the effect of pH on enzyme activity.
What is the pH when enzyme activity is highest?
Enzyme activity
2 4 6 8 10 12 14
pH
A pH 2
B pH 6
C pH 10
D pH 14
Your answer [1]
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, 3
3 Which term describes cells that have the ability to differentiate into all types of body cells?
A Adult stem cells
B Bone marrow stem cells
C Embryonic stem cells
D Skin stem cells
Your answer [1]
4 Which cell size in the table is the mode?
Cell 1 2 3 4 5 6 7 8 9
Size
0.4 0.3 0.4 0.5 0.3 0.3 0.6 0.5 0.3
(mm)
A 0.3 mm
B 0.4 mm
C 0.5 mm
D 0.6 mm
Your answer [1]
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