Enzymes
How are enzymes usually named? - correct answerEnzyme function + "-ase"
How can entire metabolic pathways involving multiple enzymes be turned off at once? -
correct answerFeedback inhibition that affects an earlier enzyme in a metabolic
pathway can cause the entire pathway to be turned off at once
How does an enzyme catalyze a reaction? - correct answerWith an enzyme, the
substrates require less activation energy to reach it's transition state, allowing a reaction
to occur more easily
How does enzyme concentration impact the rate of an enzymatic reaction? - correct
answerMore enzymes = more reactions
How does pH impact the rate of an enzymatic reaction? - correct answerEach enzyme
operates at an optimal pH
Deviation from this pH can cause deprotination or protination to not occur on the
functional groups of the amino acids that make up the enzyme, resulting in the enzyme
potentially being denatured
How does product concentration impact the rate of an enzymatic reaction? - correct
answerToo much products being produced can result in some of those products binding
to the active site of the enzyme, which can result in the reaction being prevented, or the
product being turned back into it's substrate (reversible reactions)
Aka feedback inhibition
How does substrate concentration impact the rate of an enzymatic reaction? - correct
answerMore substrate = more reactions
How does temperature impact the rate of an enzymatic reaction? - correct answerEach
enzyme operates at an optimal temperature (commonly 37 deg in humans)
Increases of this temperature can cause more vibrational energy, resulting in breaking
of the chemical bonds in amino acids that make up the enzyme (proteolysis), resulting
in the enzyme potentially being denatured as the tertiary and secondary structure of the
enzyme/protein breaks down
Is the induced-fit or lock and key model best at describing an enzyme-catalyzed
reaction? Why? - correct answerInduced fit model is better at describe a catalyzed
reaction because it explains how enzymes are able to reduce the amount of energy that
a reaction requires
How are enzymes usually named? - correct answerEnzyme function + "-ase"
How can entire metabolic pathways involving multiple enzymes be turned off at once? -
correct answerFeedback inhibition that affects an earlier enzyme in a metabolic
pathway can cause the entire pathway to be turned off at once
How does an enzyme catalyze a reaction? - correct answerWith an enzyme, the
substrates require less activation energy to reach it's transition state, allowing a reaction
to occur more easily
How does enzyme concentration impact the rate of an enzymatic reaction? - correct
answerMore enzymes = more reactions
How does pH impact the rate of an enzymatic reaction? - correct answerEach enzyme
operates at an optimal pH
Deviation from this pH can cause deprotination or protination to not occur on the
functional groups of the amino acids that make up the enzyme, resulting in the enzyme
potentially being denatured
How does product concentration impact the rate of an enzymatic reaction? - correct
answerToo much products being produced can result in some of those products binding
to the active site of the enzyme, which can result in the reaction being prevented, or the
product being turned back into it's substrate (reversible reactions)
Aka feedback inhibition
How does substrate concentration impact the rate of an enzymatic reaction? - correct
answerMore substrate = more reactions
How does temperature impact the rate of an enzymatic reaction? - correct answerEach
enzyme operates at an optimal temperature (commonly 37 deg in humans)
Increases of this temperature can cause more vibrational energy, resulting in breaking
of the chemical bonds in amino acids that make up the enzyme (proteolysis), resulting
in the enzyme potentially being denatured as the tertiary and secondary structure of the
enzyme/protein breaks down
Is the induced-fit or lock and key model best at describing an enzyme-catalyzed
reaction? Why? - correct answerInduced fit model is better at describe a catalyzed
reaction because it explains how enzymes are able to reduce the amount of energy that
a reaction requires
