TestgBankgfo
r
Lehninger Principles of Biochemistry
g g g
Fourth Edition
g
TERRYgPLATTgEU
GENEgBARBER
W.gH.gFreemangandgCompany
NewgYork
,ISBN:g0-7167-5952-7
EAN:g9780716759522
©g2005gbygW.gH.gFreemangandgCompan
ygAllgrightsgreserved.
PrintedgingthegUnitedgStatesgofgAmericag
Firstgprinting
W.gH.gFreemangandgCompanyg
41gMadisongAvenue
NewgYork,gNYg10010
Houndmills,gBasingstokegR621g6XS,gEnglandgwww.whfreeman.c
om
, Contents
Chapterg1:gFoundationsgofgBiochemistry,g1
Chapterg2:gWater,g12
Chapterg3:gAminogAcids,gPeptides,gandgProteins,g21g Chapt
erg4:gThegThree-
DimensionalgStructuregofgProteins,g38gChapterg5:gProteingF
unction,g51
Chapterg6:gEnzymes,g60
Chapterg7:gCarbohydratesgandgGlycobiology,g80gChapt
erg8:gNucleotidesgandgNucleicgAcids,g89
Chapterg9:gDNA-BasedgInformationgTechnologies,g101
Chapterg10:gLipids,g110
Chapterg11:gBiologicalgMembranesgandgTransport,g118
Chapterg12:gBiosignaling,g133
g
Chapterg13:gPrinciplesgofgBioenergetics,g145
Chapterg14:gGlycolysis,gGluconeogenesis,gandgthegPentosegPhosphategPathway,g157gChap
terg15:gPrinciplesgofgMetabolicgRegulation,g176
Chapterg16:gThegCitricgAcidgCycle,g185g
Chapterg17:gFattygAcidgCatabolism
Chapterg18:gAminogAcidgOxidationgandgthegProductiongofgUrea,g210gCh
apterg19:gOxidativegPhosphorylationgandgPhotophosphorylation,g220gCha
pterg20:gCarbohydrategBiosynthesisgingPlantsgandgBacteria,g238gChapterg
21:gLipidgBiosynthesis,g248
Chapterg22:gBiosynthesisgofgAminogAcids,gNucleotides,gandgRelatedgMolecules,g259gCha
pterg23:gIntegrationgandgHormonalgRegulationgofgMammaliangMetabolism,g272gChapterg2
4:gGenesgandgChromosomes,g280
Chapterg25:gDNAgMetabolism,g289
Chapterg26:gRNAgMetabolism,g301
Chapterg27:gProteingMetabolism,g313
Chapterg28:gRegulationgofgGenegExpression,g326
, Preface
Thisgcollectiongofgoverg1400gmultiple-choicegandgshort-
answergtestgquestionsgandgsolutionsgisgintendedgforgusegwithgNelsongandgCox:gLehningergPrincip
lesgofgBiochemistry,gFourthgEdition,gingagfirstgbiochemistrygcoursegforgupper-
divisiongundergraduatesgorgforgbeginningggraduategorgmedicalgstudents.g Moregthang25%gofgthegq
uestionsgaregnewgorgrevisedgforgthisgedition.
Asgingpriorgeditions,geachgchaptergofgthisgTestgBankghasgtwogsetsgofgquestions—
multiplegchoicegandgshortganswer—
whichgaregsequentiallygnumberedgandgwhichgreflectgthegtopicalgorganizationgofgthegtext.g Eachgq
uestiongisgtiedgtogthegmostgrelevantgsectiongheadinggofgthegchaptergthatgitgtests,gwithgtextgpagegnu
mbergreferencesgtogassistgingyourgexamgpreparation.g Thegdifficultyggradationsgare:g1gforgeasy,g2g
forgmoderate,gandg3gforgchallenging.g Theglattergrequiregeithergthegsynthesisgofgseveralgconceptsg
orgideasgtogsolvegagcomplexgproblemgorgmoregtimegtoganswergthangagquestiongofgaveragegdifficul
ty.
Althoughgmanygofgthegmultiplegchoicegquestionsgrequiregonlygthegknowledgegofgseveralg
characteristicgfacts,gsomegdemandgthinkinggthroughgagqualitativegproblem,gapplyinggangimportant
gequation,gorgperforminggquantitativegcalculations.gMostgofgthegshortganswergquestionsgrequiregw
orkinggwithgorgexplaininggangimportantgbiochemicalgprinciple,gappliedgtogagspecificgsituation.gW
heregpossible,gtheganswersgwillgprovidegagreferencegtogagspecificgpagegorgfiguregingthegtextbook.
AgcomputerizedgversiongofgthegTestgBankgisgavailablegongthegInstructor’sgResourcegCD-
gROM.gItgisgorganizedgbygchaptergasgbothg.pdfgandgWordgfiles,gwhichgcangbegcopiedgtogaghardgdr
ivegorguploadedgtogagnetworkgserver.g ThegWordgfilesgcangbegeditedgandginsertedgintogyourgowng
examsgandgquizzes.g ForgmoreginformationgongthegcomputerizedgTestgBankgandgthegInstructor’sg
ResourcegCD-ROM,gcontactgW.gH.gFreemangandgCompanygPublishers.
ThegTestgBankgforgthegThirdgEditiongprovidedgangessentialgframeworkgforgourgrevisions,
gandgmanygofgthegquestionsgaregfactuallygunchanged,gbutgweghavegmadegseveralgimportantgpedag
ogicalgalterationsgtogimprovegtheirgusefulness.gFirst,ganswersgtogthegmultiplegchoiceg questionsgar
egnowglistedgingalphabeticalgordergtogavoidgguessinggbyglocation,gandghavegbeengrephrasedgingma
nyginstancesgtogavoidgguessinggbygstructuregorgsize.g Second,gweghavegincludedgfivegoptionsgforg
multiplegchoiceganswersgwherevergfeasible.gThird,ginglinegwithgcurrentgtest-
writinggideals,gweghavegeliminated,gorgchangedgwheregpossible,gquestionsginvolvinggconfusinggd
oublegnegatives,gorgchoicesgofgtheg“Allgaregtrue,gexcept”gstyle,gasgwellgasg“Allg(orgnone)gofgthega
bove”gtypesgandgvariationsgongthesegthemes.g Allgnewgquestionsgalsogadheregtogthisgstandard.
WeghavegreliedgheavilygongthegpreviousgeditiongofgthegTestgBank,gwithgthanksgtogRhond
agScott-Ennisg(UniversitygofgWisconsin–
RivergFalls),gRogergPersellg(HuntergCollege),gandgRickgAmasinogandgMikegCoxg(Universitygofg
Wisconsin–
Madison),gwhogallgcontributedgtogseveralgofgthosegchapters;gandgGeraldgFrenkelg(RutgersgUniver
sity),gwhogcontributedggreatlygtogthegThirdgEditiongversion.g WegalsogthankgMelaniegMaysgandgN
ickgTymoczkogatgW.gH.gFreemangandgCompanygPublishersgforgtheirgeffortsgingcoordinatinggthisg
project.gFinally,gwegaregdeeplyggratefulgtogStephaniegScovillegatgRochestergforghergcheerful,gtirel
ess,gandgoutstandinggeffortsgingpreparinggthegcamera-readygcopy—
wegtrulygcouldgnotghavegdonegitgwithoutgher.
IfgingusinggthisgTestgBankgyougdiscovergambiguitiesgorgerrors,gorgcangofferganygsuggestio
nsgforgimprovement,gwegwouldgverygmuchgappreciateghearinggfromgyou.g Ingparticular,gifgyougha
veganygfavoritegquestionsgorgproblemsgfromgyourgowngexperiencegthatgyougmightglikegtogseegincl
udedgingthegnextgeditiongofgthegTestgBank,gwegwouldgbegdelightedgtogconsidergthem!g Pleasegsen
.
TerrygPlatt
gEugenegBarbe
r
r
Lehninger Principles of Biochemistry
g g g
Fourth Edition
g
TERRYgPLATTgEU
GENEgBARBER
W.gH.gFreemangandgCompany
NewgYork
,ISBN:g0-7167-5952-7
EAN:g9780716759522
©g2005gbygW.gH.gFreemangandgCompan
ygAllgrightsgreserved.
PrintedgingthegUnitedgStatesgofgAmericag
Firstgprinting
W.gH.gFreemangandgCompanyg
41gMadisongAvenue
NewgYork,gNYg10010
Houndmills,gBasingstokegR621g6XS,gEnglandgwww.whfreeman.c
om
, Contents
Chapterg1:gFoundationsgofgBiochemistry,g1
Chapterg2:gWater,g12
Chapterg3:gAminogAcids,gPeptides,gandgProteins,g21g Chapt
erg4:gThegThree-
DimensionalgStructuregofgProteins,g38gChapterg5:gProteingF
unction,g51
Chapterg6:gEnzymes,g60
Chapterg7:gCarbohydratesgandgGlycobiology,g80gChapt
erg8:gNucleotidesgandgNucleicgAcids,g89
Chapterg9:gDNA-BasedgInformationgTechnologies,g101
Chapterg10:gLipids,g110
Chapterg11:gBiologicalgMembranesgandgTransport,g118
Chapterg12:gBiosignaling,g133
g
Chapterg13:gPrinciplesgofgBioenergetics,g145
Chapterg14:gGlycolysis,gGluconeogenesis,gandgthegPentosegPhosphategPathway,g157gChap
terg15:gPrinciplesgofgMetabolicgRegulation,g176
Chapterg16:gThegCitricgAcidgCycle,g185g
Chapterg17:gFattygAcidgCatabolism
Chapterg18:gAminogAcidgOxidationgandgthegProductiongofgUrea,g210gCh
apterg19:gOxidativegPhosphorylationgandgPhotophosphorylation,g220gCha
pterg20:gCarbohydrategBiosynthesisgingPlantsgandgBacteria,g238gChapterg
21:gLipidgBiosynthesis,g248
Chapterg22:gBiosynthesisgofgAminogAcids,gNucleotides,gandgRelatedgMolecules,g259gCha
pterg23:gIntegrationgandgHormonalgRegulationgofgMammaliangMetabolism,g272gChapterg2
4:gGenesgandgChromosomes,g280
Chapterg25:gDNAgMetabolism,g289
Chapterg26:gRNAgMetabolism,g301
Chapterg27:gProteingMetabolism,g313
Chapterg28:gRegulationgofgGenegExpression,g326
, Preface
Thisgcollectiongofgoverg1400gmultiple-choicegandgshort-
answergtestgquestionsgandgsolutionsgisgintendedgforgusegwithgNelsongandgCox:gLehningergPrincip
lesgofgBiochemistry,gFourthgEdition,gingagfirstgbiochemistrygcoursegforgupper-
divisiongundergraduatesgorgforgbeginningggraduategorgmedicalgstudents.g Moregthang25%gofgthegq
uestionsgaregnewgorgrevisedgforgthisgedition.
Asgingpriorgeditions,geachgchaptergofgthisgTestgBankghasgtwogsetsgofgquestions—
multiplegchoicegandgshortganswer—
whichgaregsequentiallygnumberedgandgwhichgreflectgthegtopicalgorganizationgofgthegtext.g Eachgq
uestiongisgtiedgtogthegmostgrelevantgsectiongheadinggofgthegchaptergthatgitgtests,gwithgtextgpagegnu
mbergreferencesgtogassistgingyourgexamgpreparation.g Thegdifficultyggradationsgare:g1gforgeasy,g2g
forgmoderate,gandg3gforgchallenging.g Theglattergrequiregeithergthegsynthesisgofgseveralgconceptsg
orgideasgtogsolvegagcomplexgproblemgorgmoregtimegtoganswergthangagquestiongofgaveragegdifficul
ty.
Althoughgmanygofgthegmultiplegchoicegquestionsgrequiregonlygthegknowledgegofgseveralg
characteristicgfacts,gsomegdemandgthinkinggthroughgagqualitativegproblem,gapplyinggangimportant
gequation,gorgperforminggquantitativegcalculations.gMostgofgthegshortganswergquestionsgrequiregw
orkinggwithgorgexplaininggangimportantgbiochemicalgprinciple,gappliedgtogagspecificgsituation.gW
heregpossible,gtheganswersgwillgprovidegagreferencegtogagspecificgpagegorgfiguregingthegtextbook.
AgcomputerizedgversiongofgthegTestgBankgisgavailablegongthegInstructor’sgResourcegCD-
gROM.gItgisgorganizedgbygchaptergasgbothg.pdfgandgWordgfiles,gwhichgcangbegcopiedgtogaghardgdr
ivegorguploadedgtogagnetworkgserver.g ThegWordgfilesgcangbegeditedgandginsertedgintogyourgowng
examsgandgquizzes.g ForgmoreginformationgongthegcomputerizedgTestgBankgandgthegInstructor’sg
ResourcegCD-ROM,gcontactgW.gH.gFreemangandgCompanygPublishers.
ThegTestgBankgforgthegThirdgEditiongprovidedgangessentialgframeworkgforgourgrevisions,
gandgmanygofgthegquestionsgaregfactuallygunchanged,gbutgweghavegmadegseveralgimportantgpedag
ogicalgalterationsgtogimprovegtheirgusefulness.gFirst,ganswersgtogthegmultiplegchoiceg questionsgar
egnowglistedgingalphabeticalgordergtogavoidgguessinggbyglocation,gandghavegbeengrephrasedgingma
nyginstancesgtogavoidgguessinggbygstructuregorgsize.g Second,gweghavegincludedgfivegoptionsgforg
multiplegchoiceganswersgwherevergfeasible.gThird,ginglinegwithgcurrentgtest-
writinggideals,gweghavegeliminated,gorgchangedgwheregpossible,gquestionsginvolvinggconfusinggd
oublegnegatives,gorgchoicesgofgtheg“Allgaregtrue,gexcept”gstyle,gasgwellgasg“Allg(orgnone)gofgthega
bove”gtypesgandgvariationsgongthesegthemes.g Allgnewgquestionsgalsogadheregtogthisgstandard.
WeghavegreliedgheavilygongthegpreviousgeditiongofgthegTestgBank,gwithgthanksgtogRhond
agScott-Ennisg(UniversitygofgWisconsin–
RivergFalls),gRogergPersellg(HuntergCollege),gandgRickgAmasinogandgMikegCoxg(Universitygofg
Wisconsin–
Madison),gwhogallgcontributedgtogseveralgofgthosegchapters;gandgGeraldgFrenkelg(RutgersgUniver
sity),gwhogcontributedggreatlygtogthegThirdgEditiongversion.g WegalsogthankgMelaniegMaysgandgN
ickgTymoczkogatgW.gH.gFreemangandgCompanygPublishersgforgtheirgeffortsgingcoordinatinggthisg
project.gFinally,gwegaregdeeplyggratefulgtogStephaniegScovillegatgRochestergforghergcheerful,gtirel
ess,gandgoutstandinggeffortsgingpreparinggthegcamera-readygcopy—
wegtrulygcouldgnotghavegdonegitgwithoutgher.
IfgingusinggthisgTestgBankgyougdiscovergambiguitiesgorgerrors,gorgcangofferganygsuggestio
nsgforgimprovement,gwegwouldgverygmuchgappreciateghearinggfromgyou.g Ingparticular,gifgyougha
veganygfavoritegquestionsgorgproblemsgfromgyourgowngexperiencegthatgyougmightglikegtogseegincl
udedgingthegnextgeditiongofgthegTestgBank,gwegwouldgbegdelightedgtogconsidergthem!g Pleasegsen
.
TerrygPlatt
gEugenegBarbe
r
