Abrams' Clinical Drug Therap
g g g
y: Rationales for Nursing Practi
g g g g
ce 12th Edition Frandsen Test B
g g g g g
ank
,Abrams'gClinicalgDruggTherapy:gRationalesgforgNursinggPracticeg12thgEditiongFrandsengTestgBa
nk
Chapterg1gThegFoundationgofgPharmacology:gQualitygandgSafety
Agwomanghasgbeengprescribedgparoxetineghyd
rochloride,gwhichgisgangantidepressantgagentga
dministeredgingpillgform.gThegmedicationgisga
1.
dministeredgforghergobsessive-
compulsivegdisorder.gThisgmedicationgwillgpro
ducegwhichgofgthegfollowinggeffects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugsgthatgproducegsystemicgeffectsgaregtaken
gintogthegbody,gcirculatedgthroughgthegbloodst
reamgtogtheirgsitesgofgactiongingvariousgbodygti
ssues,gandgeventuallygeliminatedgfromgthegbod
y.gCurativegagentsgareggivengtogcuregagdisease
gprocess.gIngthisgcase,gparoxetineghydrochlori
degwillgcontrolgthegsymptomsgbutgnotgcuregthe
gdisorder.gDrugsgwithglocalgeffects,gsuchgasgsu
nscreengandglocalganesthetics,gactgmainlygatgth
egsitegofgapplication.gParoxetineghydrochlorid
egisg notg administeredgparenterally.gParenteral
gagentsgaregadministeredgsubcutaneously,gintra
muscularly,gorgintravenously.
Agpatientghasgbeengprescribedgangantibiotic.gT
hisgmedicationgisgagnaturallygoccurringgsubsta
2. ncegthatghasgbeengchemicallygmodified.
Whatgisganothergnamegforgthisgtypegofgm
edication?
A) Syntheticgdrug
B) Semisyntheticgdrug
C) Biotechnologygdrug
D) Prototypegdrug
Ans: B
Feedback:
,Abrams'gClinicalgDruggTherapy:gRationalesgforgNursinggPracticeg12thgEditiongFrandsengTestgBa
nk
Semisyntheticgdrugsg(e.g.,gmanygantibiotics)ga
regnaturallygoccurringgsubstancesgthatghavegbe
engchemicallygmodified.gSyntheticgdrugsgareg
moregstandardizedgingtheirgchemicalgcharacter
istics,gmoregconsistentg ing theirgeffects,gandgle
ssglikelygtogproducegallergicgreactions.gBiotec
hnologygdrugsginvolvegmanipulatingg DNAgan
dg RNAgandgrecombiningggenesgintoghybridgm
oleculesgthatgcangbeginsertedgintoglivinggorgan
isms.
Prototypegdrugsgaregthegfirstgdruggofgagpa
rticularggroupgtogbegdeveloped.
m
Agpatientgisgadministeredgmorphine.gMorphin
egisgagprototypicalgdruggthatgcangbegclassifiedg
3.
in
differentgways.gWhichgofgthegfollowinggclassif
icationsgappliesgtogmorphine?
A) Centralgnervousgsystemgdepressant
B) Centralgnervousgsystemgstimulant
C) Anti-inflammatory
D) Antihypertensive
Ans: A
Feedback:
Drugsgaregclassifiedgaccordinggtogtheirgeffectsg
ongparticulargbodygsystems,gtheirgtherapeuticg
uses,gandgtheirgchemicalgcharacteristics.gForge
xample,gmorphinegcangbegclassifiedgasgagcentr
algnervousgsystemgdepressantgandgagnarcoticgo
rgopioidganalgesic.gAgcentralgnervousgsystemgs
timulantg increasesg attentiong andgraisesgmood.
gAnganti-
inflammatorygagentgdecreasesginflammationgat
gthegsitegofgtissuegorgjointginflammation.gAnga
ntihypertensivegagentgreducesgbloodgpressure.
Agpatientgisgadministeredgamoxicilling(Amoxi
l).gTheggenericgnamegofgthis
4.
medicationgindicatesgthatgitgbelongsgtogwhichg
drugggroup?
A) Selectivegserotoningreuptakeginhibitors
B) Diuretics
C) Penicillins
D) ACEginhibitors
Ans: C
, Abrams'gClinicalgDruggTherapy:gRationalesgforgNursinggPracticeg12thgEditiongFrandsengTestgBa
nk
Feedback:
Theggenericgnamegoftengindicatesgthegdrugggr
oupg(e.g.,gdrugsgwithggenericgnamesgendinggi
ng“cillin”garegpenicillins).gSelectivegserotonin
greuptakeginhibitorsgaregmedicationsgthatghav
egantidepressantgeffects;gSSRIgisgagbroadgclas
sification,gnotgaggenericgname.gDiureticsgareg
medicationsgthatgincreasegurinegoutput;gdiuret
icgisgagbroadgclassification,gnotgaggenericgnam
e.gACEginhibitorgisgthegbroadgclassificationgf
orgthegangiotensin-
convertinggenzymeginhibitors,gnotgtheggeneric
gname.
www.mynursingtestprep.co Thegadministrationgofgdiphenhydramineg( B e
m 5.
n a d r y l ) , gwhichgisgangover-the-counter
medication,gisgregulatedgbygwhichggovernment
agency?
A) PublicgHealthgService
B) FederalgTradegCommission
OccupationalgSafetygandgHealthgAdministrati
C) on
D) FoodgandgDruggAdministration
Ans: D
Feedback:
ThegFoodgandgDruggAdministrationgapproves
gdrugsgforgover-the-
countergavailability,gincludinggthegtransfergofg
drugsgfromgprescriptiongtogOTCgstatus,gandg
maygrequiregclinicalgtrialsgtogdeterminegthegsa
fetygandgeffectivenessgofgOTCguse.gThegPubli
cgHealthgServicegisgregulatedgbygthegstategtog
maintaingtheghealthgofgindividualgcitizensgofgt
hegstate.gThegFederalgTradegCommissiongreg
ulatesgimportsgandgexportsgthroughoutgthegnat
ion.
ThegOccupationalgSafetygandgHealth
Administrationgregulatesgsafetygwithingthegwo
rkplace.
Thegadministrationgofganabolicgsteroidsgisgreg
6. ulatedgbygwhichgofgthegfollowingglaws?
A) ThegFood,gDrug,gandgCosmeticgActgofg1938
ThegComprehensivegDruggAbusegPreventionga
B) ndgControlgAct
C) ThegHarrisongNarcoticgAct
g g g
y: Rationales for Nursing Practi
g g g g
ce 12th Edition Frandsen Test B
g g g g g
ank
,Abrams'gClinicalgDruggTherapy:gRationalesgforgNursinggPracticeg12thgEditiongFrandsengTestgBa
nk
Chapterg1gThegFoundationgofgPharmacology:gQualitygandgSafety
Agwomanghasgbeengprescribedgparoxetineghyd
rochloride,gwhichgisgangantidepressantgagentga
dministeredgingpillgform.gThegmedicationgisga
1.
dministeredgforghergobsessive-
compulsivegdisorder.gThisgmedicationgwillgpro
ducegwhichgofgthegfollowinggeffects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugsgthatgproducegsystemicgeffectsgaregtaken
gintogthegbody,gcirculatedgthroughgthegbloodst
reamgtogtheirgsitesgofgactiongingvariousgbodygti
ssues,gandgeventuallygeliminatedgfromgthegbod
y.gCurativegagentsgareggivengtogcuregagdisease
gprocess.gIngthisgcase,gparoxetineghydrochlori
degwillgcontrolgthegsymptomsgbutgnotgcuregthe
gdisorder.gDrugsgwithglocalgeffects,gsuchgasgsu
nscreengandglocalganesthetics,gactgmainlygatgth
egsitegofgapplication.gParoxetineghydrochlorid
egisg notg administeredgparenterally.gParenteral
gagentsgaregadministeredgsubcutaneously,gintra
muscularly,gorgintravenously.
Agpatientghasgbeengprescribedgangantibiotic.gT
hisgmedicationgisgagnaturallygoccurringgsubsta
2. ncegthatghasgbeengchemicallygmodified.
Whatgisganothergnamegforgthisgtypegofgm
edication?
A) Syntheticgdrug
B) Semisyntheticgdrug
C) Biotechnologygdrug
D) Prototypegdrug
Ans: B
Feedback:
,Abrams'gClinicalgDruggTherapy:gRationalesgforgNursinggPracticeg12thgEditiongFrandsengTestgBa
nk
Semisyntheticgdrugsg(e.g.,gmanygantibiotics)ga
regnaturallygoccurringgsubstancesgthatghavegbe
engchemicallygmodified.gSyntheticgdrugsgareg
moregstandardizedgingtheirgchemicalgcharacter
istics,gmoregconsistentg ing theirgeffects,gandgle
ssglikelygtogproducegallergicgreactions.gBiotec
hnologygdrugsginvolvegmanipulatingg DNAgan
dg RNAgandgrecombiningggenesgintoghybridgm
oleculesgthatgcangbeginsertedgintoglivinggorgan
isms.
Prototypegdrugsgaregthegfirstgdruggofgagpa
rticularggroupgtogbegdeveloped.
m
Agpatientgisgadministeredgmorphine.gMorphin
egisgagprototypicalgdruggthatgcangbegclassifiedg
3.
in
differentgways.gWhichgofgthegfollowinggclassif
icationsgappliesgtogmorphine?
A) Centralgnervousgsystemgdepressant
B) Centralgnervousgsystemgstimulant
C) Anti-inflammatory
D) Antihypertensive
Ans: A
Feedback:
Drugsgaregclassifiedgaccordinggtogtheirgeffectsg
ongparticulargbodygsystems,gtheirgtherapeuticg
uses,gandgtheirgchemicalgcharacteristics.gForge
xample,gmorphinegcangbegclassifiedgasgagcentr
algnervousgsystemgdepressantgandgagnarcoticgo
rgopioidganalgesic.gAgcentralgnervousgsystemgs
timulantg increasesg attentiong andgraisesgmood.
gAnganti-
inflammatorygagentgdecreasesginflammationgat
gthegsitegofgtissuegorgjointginflammation.gAnga
ntihypertensivegagentgreducesgbloodgpressure.
Agpatientgisgadministeredgamoxicilling(Amoxi
l).gTheggenericgnamegofgthis
4.
medicationgindicatesgthatgitgbelongsgtogwhichg
drugggroup?
A) Selectivegserotoningreuptakeginhibitors
B) Diuretics
C) Penicillins
D) ACEginhibitors
Ans: C
, Abrams'gClinicalgDruggTherapy:gRationalesgforgNursinggPracticeg12thgEditiongFrandsengTestgBa
nk
Feedback:
Theggenericgnamegoftengindicatesgthegdrugggr
oupg(e.g.,gdrugsgwithggenericgnamesgendinggi
ng“cillin”garegpenicillins).gSelectivegserotonin
greuptakeginhibitorsgaregmedicationsgthatghav
egantidepressantgeffects;gSSRIgisgagbroadgclas
sification,gnotgaggenericgname.gDiureticsgareg
medicationsgthatgincreasegurinegoutput;gdiuret
icgisgagbroadgclassification,gnotgaggenericgnam
e.gACEginhibitorgisgthegbroadgclassificationgf
orgthegangiotensin-
convertinggenzymeginhibitors,gnotgtheggeneric
gname.
www.mynursingtestprep.co Thegadministrationgofgdiphenhydramineg( B e
m 5.
n a d r y l ) , gwhichgisgangover-the-counter
medication,gisgregulatedgbygwhichggovernment
agency?
A) PublicgHealthgService
B) FederalgTradegCommission
OccupationalgSafetygandgHealthgAdministrati
C) on
D) FoodgandgDruggAdministration
Ans: D
Feedback:
ThegFoodgandgDruggAdministrationgapproves
gdrugsgforgover-the-
countergavailability,gincludinggthegtransfergofg
drugsgfromgprescriptiongtogOTCgstatus,gandg
maygrequiregclinicalgtrialsgtogdeterminegthegsa
fetygandgeffectivenessgofgOTCguse.gThegPubli
cgHealthgServicegisgregulatedgbygthegstategtog
maintaingtheghealthgofgindividualgcitizensgofgt
hegstate.gThegFederalgTradegCommissiongreg
ulatesgimportsgandgexportsgthroughoutgthegnat
ion.
ThegOccupationalgSafetygandgHealth
Administrationgregulatesgsafetygwithingthegwo
rkplace.
Thegadministrationgofganabolicgsteroidsgisgreg
6. ulatedgbygwhichgofgthegfollowingglaws?
A) ThegFood,gDrug,gandgCosmeticgActgofg1938
ThegComprehensivegDruggAbusegPreventionga
B) ndgControlgAct
C) ThegHarrisongNarcoticgAct
