FOCUS ON NURSING PHARMACOLOGY TEST BANK (
g g g g g g
8TH EDITION BY KARCH) WITH 1 -59 CHAPTERS.
g g g g g g g
,Chapterg 01g -g Introductiong tog Drugs
Agnursegworkingg ingradiologyg administersg iodinegtog ag patientgwhogisghavinggagcomputedgtomography(C
T)gscan.gThegnursegworkinggongthegoncologygunitgadministersgchemotherapygtogpatientsgwhoghaveg
cancer.gAtgthegPublicgHealthgDepartment,gagnursegadministersgagmeasles-mumps-
rubellag(MMR)gvaccineg tog ag 14-month-
oldg childg asg ag routineg immunization.g Whichg branchg ofg pharmacologyg bestgdescribesgthegactionsg
ofgallg threegnurses?
Pharmacoeconomicsg
Pharmacotherapeuticsg
Pharmacodynamicsg
PharmacokineticsgA
ns: B
Feedback:
Pharmacologygisgthegstudygofgthegbiologicgeffectsgofgchemicals.gNursesgareginvolvedgwithgclinicalg
pharmacologyg orgpharmacotherapeutics,g whichgisg agbranchgofgpharmacologyg thatgdealsg withg theg usesgo
fgdrugsgtogtreat,gprevent,gandgdiagnosegdisease.gThegradiologygnursegisgadministeringgagdruggtoghel
pgdiagnosegagdisease.gThegoncologygnursegisgadministeringgagdruggtoghelpgtreatgagdisease.
Pharmacoeconomicsg includesg anygcostsg involvedging drugg therapy.g Pharmacodynamicsg involvesg howg ag
druggaffectsgthegbodygandgpharmacokineticsgisghowgthegbodygactsgongthegbody.
Agphysiciang hasgorderedg intramuscularg (IM)g injectionsg ofgmorphine,g agnarcotic,geveryg 4ghoursgasg needed
forgpaingingagmotorgvehiclegaccidentgvictim.gThegnursegisgawaregthisgdrugghasgaghighgabusegpot
ential.gUndergwhatgcategorygwouldgmorphinegbegclassified?
SchedulegIgS
chedulegIIgS
chedulegIIIg
SchedulegIV
gAns: B
Feedback:
Narcoticsg withgaghighgabusegpotentialgareg classifiedgasg SchedulegIIgdrugsgbecausegofgsevereg dependence
, liability.gSchedulegIgdrugsghaveghighgabusegpotentialgandgnogacceptedgmedicalguse.gSchedulegIIIgdr
ugsghavegaglessergabusegpotentialgthangIIgandgangacceptedgmedicalguse.gSchedulegIVgdrugsghavegl
owgabusegpotentialgandglimitedgdependencegliability.
Whenginvolvedgingphaseg IIIgdruggevaluationg studies,g whatg responsibilitiesg wouldg theg nurseghave?g
Workinggwithganimalsgwhogareggivengexperimentalgdrugs
ChoosinggappropriategpatientsgtogbeginvolvedgingthegdruggstudygMonit
oringgandgobservinggpatientsgcloselygforgadversegeffectsgConductingg r
esearchgtogdetermineg effectivenessgofgtheg druggAns: C
Feedback:
PhasegIIIgstudiesginvolvegusegofgagdrugg ingagvastgclinicalgpopulationg ingwhichgpatientsgaregaskedg togrec
ordganyg symptomsg theyg experienceg whileg takingg theg drugs.g Nursesg mayg beg responsibleg forg helpingg c
ollectgandganalyzegtheginformationgtogbegsharedg withgtheg FoodgandgDruggAdministrationg (FDA)g butgw
ouldg notgconductgresearchgindependentlygbecausegnursesgdognotgprescribegmedications.gUsegofganimalsg
ingdruggtestinggisgdoneging thegpreclinicalgtrials.gSelectgpatientsgwhogareginvolvedgingphasegIIgstudiesgtog
participateging studiesg whereg theg participantsg haveg theg diseaseg theg drugg isg intendedg tog treat.g Theseg pati
entsg aregmonitoredgcloselyg forgdruggactiongandgadverseg effects.gPhasegIgstudiesg involveg healthyg human
g volunteersgwhog areg usuallyg paidg forg theirg participation.g Nursesg mayg observeg forg adverseg effectsg andg
toxicity.
Whatgconceptgisgconsideredg wheng genericg drugsg areg substitutedg forgbrandg nameg drugs?gBioavailab
ility
Criticalgconcentration
gDistribution
Half-
lifegAns: A
Feedback:
Bioavailabilitygisgthegportiongofgagdosegofgagdruggthatgreachesgthegsystemicg circulationg andgisgavailable
g togactgongbodygcells.gBindersgusedgingaggenericgdruggmaygnotgbegthegsamegasgthosegusedgingthegbr
andgnamegdrug.gTherefore,gthegwaygthegbodygbreaksgdowngandgusesgthegdruggmaygdiffer,gwhichgm
aygeliminategaggenericgdruggsubstitution.gCriticalgconcentrationgisgthegamountgofgagdruggthatgisgnee
dedgtogcausegagtherapeuticgeffectgandgshouldgnotgdiffergbetweenggenericgandgbrandgnamegmedication
s.
Distributiongisgthegphaseg ofg pharmacokinetics,g whichginvolvesg theg movementg ofg ag druggtog theg body’sg
tissuesg andgisg the
, sameg inggenericgandgbrandg namegdrugs.gAgdrug’sghalf-
lifegisgthegtimeg itgtakesgforgthegamountgofg druggtogdecreaseg tog halfg theg peakg level,g whichg shouldg notg chan
geg wheng substitutingg ag genericg medication.
Agnursegisgassessinggthegpatient’sghomeg medicationguse.gAfterglisteninggtogthegpatientglistgcurrentgmedica
tions,gthegnursegasksgwhatgprioritygquestion?
Dogyougtakeganyg genericg medications?
Areganygofgtheseg medicationsgorphang drugs?
Aregtheseg medicationsg safeg togtakeg duringg pregnancy?g
Dogyougtakeganygover-the-countergmedications?
Ans: D
Feedback:
Itgisgimportantgforgthegnursegtogspecificallygquestiongusegofgover-the-
countergmedicationsgbecausegpatientsg maygnotgconsidergthemg important.gThegpatientgisgunlikelyg togkn
owgtheg meaninggofgorphang drugsgunlessgtheygtoogareghealthgcaregproviders.gSafetygduringgpregnanc
y,gusegofgaggenericgmedication,gorgclassificationgofgorphangdrugsgaregthingsgthegpatientgwouldgbegu
nablegtoganswergbutgcouldgbegfoundgingreferencegbooksgifgthegnursegwishesgtogresearchgthem.
Aftergcompletingg agcourseg ongpharmacologyg forg nurses,g whatgwillg theg nursegknow?gEveryth
inggnecessarygforgsafegandgeffectivegmedicationgadministration
Currentgpharmacologicgtherapy;gthegnursegwillgnotgrequiregongoinggeducationgforg5gyears.g
Generalg drugginformation;gthegnurseg cangconsultgag druggguideg forg specificg drugg informatio
n.gThegdruggactionsgthatgaregassociatedgwithgeachgclassificationgofgmedicationgAns:
C
Feedback:
Aftergcompletinggagpharmacologyg courseg nursesg willghaveggeneralgdrugginformationg neededgforg safeg a
ndgeffectiveg medicationg administrationgbutg willgneedgtogconsultgagdruggguidegforgspecificgdrugginforma
tiongbeforegadministeringganygmedication.gPharmacologygisgconstantlygchanging,g withg newg drugsg ent
eringgthegmarketgandgnewgusesgforg existinggdrugsg identified.gContinuingg educationgingpharmacologygis
gessentialgtogsafegpractice.gNursesgtendgtogbecomegfamiliargwithgthegmedicationsgtheygadministerg mostg
often,gbutgtheregwillgalwaysgbegagneedgtogresearchgnewgdrugsgandgalsogthoseg thegnursegisgnotgfamiliarg
withgbecausegnognursegknowsgallgmedications.
g g g g g g
8TH EDITION BY KARCH) WITH 1 -59 CHAPTERS.
g g g g g g g
,Chapterg 01g -g Introductiong tog Drugs
Agnursegworkingg ingradiologyg administersg iodinegtog ag patientgwhogisghavinggagcomputedgtomography(C
T)gscan.gThegnursegworkinggongthegoncologygunitgadministersgchemotherapygtogpatientsgwhoghaveg
cancer.gAtgthegPublicgHealthgDepartment,gagnursegadministersgagmeasles-mumps-
rubellag(MMR)gvaccineg tog ag 14-month-
oldg childg asg ag routineg immunization.g Whichg branchg ofg pharmacologyg bestgdescribesgthegactionsg
ofgallg threegnurses?
Pharmacoeconomicsg
Pharmacotherapeuticsg
Pharmacodynamicsg
PharmacokineticsgA
ns: B
Feedback:
Pharmacologygisgthegstudygofgthegbiologicgeffectsgofgchemicals.gNursesgareginvolvedgwithgclinicalg
pharmacologyg orgpharmacotherapeutics,g whichgisg agbranchgofgpharmacologyg thatgdealsg withg theg usesgo
fgdrugsgtogtreat,gprevent,gandgdiagnosegdisease.gThegradiologygnursegisgadministeringgagdruggtoghel
pgdiagnosegagdisease.gThegoncologygnursegisgadministeringgagdruggtoghelpgtreatgagdisease.
Pharmacoeconomicsg includesg anygcostsg involvedging drugg therapy.g Pharmacodynamicsg involvesg howg ag
druggaffectsgthegbodygandgpharmacokineticsgisghowgthegbodygactsgongthegbody.
Agphysiciang hasgorderedg intramuscularg (IM)g injectionsg ofgmorphine,g agnarcotic,geveryg 4ghoursgasg needed
forgpaingingagmotorgvehiclegaccidentgvictim.gThegnursegisgawaregthisgdrugghasgaghighgabusegpot
ential.gUndergwhatgcategorygwouldgmorphinegbegclassified?
SchedulegIgS
chedulegIIgS
chedulegIIIg
SchedulegIV
gAns: B
Feedback:
Narcoticsg withgaghighgabusegpotentialgareg classifiedgasg SchedulegIIgdrugsgbecausegofgsevereg dependence
, liability.gSchedulegIgdrugsghaveghighgabusegpotentialgandgnogacceptedgmedicalguse.gSchedulegIIIgdr
ugsghavegaglessergabusegpotentialgthangIIgandgangacceptedgmedicalguse.gSchedulegIVgdrugsghavegl
owgabusegpotentialgandglimitedgdependencegliability.
Whenginvolvedgingphaseg IIIgdruggevaluationg studies,g whatg responsibilitiesg wouldg theg nurseghave?g
Workinggwithganimalsgwhogareggivengexperimentalgdrugs
ChoosinggappropriategpatientsgtogbeginvolvedgingthegdruggstudygMonit
oringgandgobservinggpatientsgcloselygforgadversegeffectsgConductingg r
esearchgtogdetermineg effectivenessgofgtheg druggAns: C
Feedback:
PhasegIIIgstudiesginvolvegusegofgagdrugg ingagvastgclinicalgpopulationg ingwhichgpatientsgaregaskedg togrec
ordganyg symptomsg theyg experienceg whileg takingg theg drugs.g Nursesg mayg beg responsibleg forg helpingg c
ollectgandganalyzegtheginformationgtogbegsharedg withgtheg FoodgandgDruggAdministrationg (FDA)g butgw
ouldg notgconductgresearchgindependentlygbecausegnursesgdognotgprescribegmedications.gUsegofganimalsg
ingdruggtestinggisgdoneging thegpreclinicalgtrials.gSelectgpatientsgwhogareginvolvedgingphasegIIgstudiesgtog
participateging studiesg whereg theg participantsg haveg theg diseaseg theg drugg isg intendedg tog treat.g Theseg pati
entsg aregmonitoredgcloselyg forgdruggactiongandgadverseg effects.gPhasegIgstudiesg involveg healthyg human
g volunteersgwhog areg usuallyg paidg forg theirg participation.g Nursesg mayg observeg forg adverseg effectsg andg
toxicity.
Whatgconceptgisgconsideredg wheng genericg drugsg areg substitutedg forgbrandg nameg drugs?gBioavailab
ility
Criticalgconcentration
gDistribution
Half-
lifegAns: A
Feedback:
Bioavailabilitygisgthegportiongofgagdosegofgagdruggthatgreachesgthegsystemicg circulationg andgisgavailable
g togactgongbodygcells.gBindersgusedgingaggenericgdruggmaygnotgbegthegsamegasgthosegusedgingthegbr
andgnamegdrug.gTherefore,gthegwaygthegbodygbreaksgdowngandgusesgthegdruggmaygdiffer,gwhichgm
aygeliminategaggenericgdruggsubstitution.gCriticalgconcentrationgisgthegamountgofgagdruggthatgisgnee
dedgtogcausegagtherapeuticgeffectgandgshouldgnotgdiffergbetweenggenericgandgbrandgnamegmedication
s.
Distributiongisgthegphaseg ofg pharmacokinetics,g whichginvolvesg theg movementg ofg ag druggtog theg body’sg
tissuesg andgisg the
, sameg inggenericgandgbrandg namegdrugs.gAgdrug’sghalf-
lifegisgthegtimeg itgtakesgforgthegamountgofg druggtogdecreaseg tog halfg theg peakg level,g whichg shouldg notg chan
geg wheng substitutingg ag genericg medication.
Agnursegisgassessinggthegpatient’sghomeg medicationguse.gAfterglisteninggtogthegpatientglistgcurrentgmedica
tions,gthegnursegasksgwhatgprioritygquestion?
Dogyougtakeganyg genericg medications?
Areganygofgtheseg medicationsgorphang drugs?
Aregtheseg medicationsg safeg togtakeg duringg pregnancy?g
Dogyougtakeganygover-the-countergmedications?
Ans: D
Feedback:
Itgisgimportantgforgthegnursegtogspecificallygquestiongusegofgover-the-
countergmedicationsgbecausegpatientsg maygnotgconsidergthemg important.gThegpatientgisgunlikelyg togkn
owgtheg meaninggofgorphang drugsgunlessgtheygtoogareghealthgcaregproviders.gSafetygduringgpregnanc
y,gusegofgaggenericgmedication,gorgclassificationgofgorphangdrugsgaregthingsgthegpatientgwouldgbegu
nablegtoganswergbutgcouldgbegfoundgingreferencegbooksgifgthegnursegwishesgtogresearchgthem.
Aftergcompletingg agcourseg ongpharmacologyg forg nurses,g whatgwillg theg nursegknow?gEveryth
inggnecessarygforgsafegandgeffectivegmedicationgadministration
Currentgpharmacologicgtherapy;gthegnursegwillgnotgrequiregongoinggeducationgforg5gyears.g
Generalg drugginformation;gthegnurseg cangconsultgag druggguideg forg specificg drugg informatio
n.gThegdruggactionsgthatgaregassociatedgwithgeachgclassificationgofgmedicationgAns:
C
Feedback:
Aftergcompletinggagpharmacologyg courseg nursesg willghaveggeneralgdrugginformationg neededgforg safeg a
ndgeffectiveg medicationg administrationgbutg willgneedgtogconsultgagdruggguidegforgspecificgdrugginforma
tiongbeforegadministeringganygmedication.gPharmacologygisgconstantlygchanging,g withg newg drugsg ent
eringgthegmarketgandgnewgusesgforg existinggdrugsg identified.gContinuingg educationgingpharmacologygis
gessentialgtogsafegpractice.gNursesgtendgtogbecomegfamiliargwithgthegmedicationsgtheygadministerg mostg
often,gbutgtheregwillgalwaysgbegagneedgtogresearchgnewgdrugsgandgalsogthoseg thegnursegisgnotgfamiliarg
withgbecausegnognursegknowsgallgmedications.
