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Chapterg1.gDrugsgUsedgingTreatinggBacterialgDiseases
MultiplegChoice
Identifygthegchoicegthatgbestgcompletesgthegstatementgorganswersgthegquestion
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gggggggggggg 1.gFactorsgthatgplacegagpatientgatgriskgofgdevelopinggangantimicrobial-
resistantgorganismginclude:
1. Agegoverg50gyears
2. Schoolgattendanceg3. TravelgwithingthegU.S.
4.gInappropriategusegofgantimicrobials
g g 2.gInfantsgandgyounggchildrengaregatghighergriskgofgdevelopinggantibiotic-
resistantginfectionsgduegto:
1. Developmentalgdifferencesgingpharmacokineticsgofgthegantibioticsgingchildren
2. Thegfactgthatgchildrengthisgagegaregmoreglikelygtogbegingdaycare
gandgexposedgtogpathogensgfromgothergchildren
3. Parentsgofgyounggchildrenginsistinggongpreventivegantibioticsgsogtheyg
don’tgmissgworkgwhengtheirgchildgisgsick
4. Immunosuppressiongfromgthegmultiplegvaccinesgtheygreceivegingthegfirstg2gyearsgofg
life
g g 3.gProvidersgshouldgusegangantibiogramgwhengprescribing.gAngantibiogramgis:
1. ThegothergnamegforgthegCentersgforgDiseasegControlgguidelinesgforgprescribingganti
biotics
2. Angalgorithmgusedgforgprescribinggantibioticsgforgcertainginfections
3. ThegreferencegalsogknowngasgthegPinkgBook,gpublishedgbygthegCentersgforgDiseaseg
Control
4. Agchartgofgtheglocalgresistancegpatternsgtogantibioticsgdevelopedgbyglaboratories
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g g 4.gTheregisgoftengcross-sensitivitygandgcross-
resistancegbetweengpenicillinsgandgcephalosporinsgbecause:
1. Renalgexcretiongisgsimilargingbothgclassesgofgdrugs.
2. Whengthesegdruggclassesgaregmetabolizedgingtheglivergtheygbothgp
roducegresistantgenzymes.
3. Bothgdruggclassesgcontaingagbeta-
lactamgringgthatgisgvulnerablegtogbeta-lactamase-
producinggorganisms.
g
4. Theregisgnotgangissuegwithgcross-
resistancegbetweengthegpenicillinsgandgcephalosporins.
g
5.gJonathanghasgbeengdiagnosedgwithgstrepgthroatgandgneedsgagprescriptiongfo
rgangantibiotic.gHegsaysgtheglastgtimegheghadgpenicillinghegdevelopedgagred,gblotch
ygrash.gAngappropriategantibioticgtogprescribegwouldgbe:
1. PenicillingVK,gbecauseghisgrashgdoesgnotgsoundglikegagseriousgrash
2. Amoxicillin
3. Cefadroxilg(Duricef)
4. Azithromycin
g 6.gSarahgisgag25-year-
oldgfemalegwhogisg8gweeksgpregnantgandghasgagurinarygtractginfection.gWhatgw
ouldgbegthegappropriategantibioticgtogprescribegforgher?
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1. Ciprofloxacing(Cipro)
2. Amoxicilling(Trimox)
3. Doxycycline
4. Trimethoprim-sulfamethoxazoleg(Septra)
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