ACTUAL EXAM TEST STUDY GUIDE | ACCURATE
EXPERT VERIFIED FOR GUARANTEED PASS | LATEST
UPDATE Terms in this set (120) Climacteric phase The
period of endocrinologic, somatic, and transitory
psychologic changes that
Climacteric phase - answer-The period of endrocrinologic, somatic, and
transitory psychologic changes that occur around the time of menopause.
Early menopause - answer-LMP before age 45
Late menopause - answer-LMP after age 54
what are considered the 'adrenal androgens'? - answer-DHEA, DHEAS,
Androstenedione.
Aldosterone secretion from the zona reticularis in the adrenal gland is
regulated by 3 main factors. - answer-Angiotensin II, potassium concentration,
adrenocorticotropic hormone secreted by the anterior pituitary.
What part of the pituitary gland secretes adrenocorticotropic hormone? -
answer-Anterior pituitary. The posterior only secretes vasopressin and
oxytosin.
,Cortisol and HRT - answer-Most serum cortisol circulates bound to cortisol
binding globulin.
Oral estrogen increases the cortisol binding globulin, which increases total
cortisol concentration.
Oral tamoxifen acts similarly.
Transdermal does not increase it, so it has a minimal effect on serum cortisol
concentration.
Do cortisol levels associate with VMS severity? - answer-No, cortisol levels
have NOT been associated with more severe VMS.
Local DHEA has been proven to help with what? - answer-vaginal pain and
dyspareunia
How to DX POI? - answer-Menstrual disturbance-oligomenorrhea or
amenorrhea for at least 4 months.
AND
elevated FSH over 25 on two occasions at least 4 weeks apart.
, Anyone <40years old who misses 3+ consecutive cycles gets these labs -
answer-prolactin
FSH
estradiol
TSH
pregnancy test
treatment of POI - answer-100 microgram estradiol patch
1.25 mg CEE
2mg oral estradiol
Primary ovarian insufficiency - answer-Menopause that occurs before age 40
Early menopause transition (stage -2) - answer-Persistent difference of 7 days
or more in the length of consecutive cycles.
Late menopause transition (stage -1) - answer-60 or more consecutive days of
amenorrhea
Luteal out of phase event (LOOP) - answer-Explains why some perimenopausal
women have elevated estrogen level sometimes...In the early menopause
transition, elevated FSH levels are adequate to recruit a second follicle which
results in a follicular phase-like rise in estradiol secretion superimposed on the
mid-to-late luteal phase of the ongoing ovulatory cycle.