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Lecture notes Cells (BIO0001)

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Detailed biology lecture notes exploring glycolysis, the initial stage of carbohydrate catabolism in cells. These notes provide an in-depth understanding of the ten sequential enzymatic reactions that convert glucose into pyruvate, generating a net gain of ATP and NADH. Learn about the regulation of glycolysis and its crucial role as a central pathway in cellular energy metabolism, linking to further stages of cellular respiration or fermentation.

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BIO – Week 7 – Lecture 1 – video 1 – 28/4/25 – Glycolysis:

Glycolysis and CAC – The complete Oxidation of
Glucose
Food molecules are broken down in 3 stages to
produce ATP:
Digestion: Enzymes break down large polymers
into monomers. Monomers enter cells for
oxidation.
Glycolysis: glucose is partially oxidised into 3
carbon molecule Pyruvate
Pyruvate is oxidised into Acetyl CoA – Transition
from cytosol to mitochondria
Citric Acid Cycle: Complete oxidation of Acetyl
CoA

Glycolysis: 10 small steps, each one catalysed by
a specific enzymes. (when you break things
down in lots of small steps the Gibs free energy
available is released one step at a time hence
there are more occasions for energy to be
stored in carrier molecules).

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