PMC EXAM 2 PRACTICE QUESTIONS & ANSWERS
Which of the following is NOT GABAergic?
a. buspirone
b. eszopiclone
c. pentobarbital
d. lorazepam - Answers :buspirone
GABA A receptors are important for regulating the influx of:
a. sodium
b. potassium
c. calcium
d. chloride - Answers :chloride
The hypnotic effect of ramelteon is attributed to its ability to:
a. mimic the actions of melatonin
b. act as a partial agonist at the 5-HT1A receptors
c. allosterically enhance the binding/effects of GABA at the GABAA receptors
d. act as an agonist at the dopamine D2 receptors - Answers :mimic the actions of
melatonin
A patient who takes diazepam for insomnia is tested for drugs of abuse at his place of
employment. The drug screen is positive for diazepam and oxazepam (another
benzodiazepine). The patient is flagged for disciplinary measure since they did not have
evidence of a prescription for oxazepam. Why is this decision wrong/incorrect? -
Answers :diazepam is metabolized in the liver to diazepam
Patients that take amitriptyline and imipramine are also, in effect, taking nortriptyline and
desipramine, respectively. Why is this? - Answers :nortripytline is the active metabolite
for amitriptyline. desipramine is the active metabolite for imipramine
15. Which of the following hypnotic drugs is an orexin receptor antagonist?
a. eszopiclone
b. ramelteon
c. zolpidem
d. suvorexant - Answers :suvorexant
Buspirone exerts its anxiolytic effects by acting as a partial agonist at the:
a. orexin-1 and orexin-2 receptors
b. serotonin 5-HT1A receptors
c. melatonin MT1 and MT2 receptors
d. GABA A receptors - Answers :serotonin 5-HT1A receptors
Which of the following is NOT GABAergic?
a. buspirone
b. eszopiclone
c. pentobarbital
d. lorazepam - Answers :buspirone
GABA A receptors are important for regulating the influx of:
a. sodium
b. potassium
c. calcium
d. chloride - Answers :chloride
The hypnotic effect of ramelteon is attributed to its ability to:
a. mimic the actions of melatonin
b. act as a partial agonist at the 5-HT1A receptors
c. allosterically enhance the binding/effects of GABA at the GABAA receptors
d. act as an agonist at the dopamine D2 receptors - Answers :mimic the actions of
melatonin
A patient who takes diazepam for insomnia is tested for drugs of abuse at his place of
employment. The drug screen is positive for diazepam and oxazepam (another
benzodiazepine). The patient is flagged for disciplinary measure since they did not have
evidence of a prescription for oxazepam. Why is this decision wrong/incorrect? -
Answers :diazepam is metabolized in the liver to diazepam
Patients that take amitriptyline and imipramine are also, in effect, taking nortriptyline and
desipramine, respectively. Why is this? - Answers :nortripytline is the active metabolite
for amitriptyline. desipramine is the active metabolite for imipramine
15. Which of the following hypnotic drugs is an orexin receptor antagonist?
a. eszopiclone
b. ramelteon
c. zolpidem
d. suvorexant - Answers :suvorexant
Buspirone exerts its anxiolytic effects by acting as a partial agonist at the:
a. orexin-1 and orexin-2 receptors
b. serotonin 5-HT1A receptors
c. melatonin MT1 and MT2 receptors
d. GABA A receptors - Answers :serotonin 5-HT1A receptors
