additive interactions - CORRECT ANSWER>>>>meds work the same amount together or
individually
synergistic interactions - CORRECT ANSWER>>>>meds work together to have greater effect
pathway of meds through body - CORRECT ANSWER>>>>mouth
esophagus
stomach
small intestine
hepatic portal vein
liver
CYP-450 enzyme system
veins
albumin
right side of heart
lungs
left side of heart
arteries
target tissue (cell)
large intestines--> stool
kidneys--> urine
CYP 450 enzyme system - CORRECT ANSWER>>>>drug metabolism (first pass)
once drug is metabolized it is - CORRECT ANSWER>>>>excreted
active drug is - CORRECT ANSWER>>>>free floating
drug bound to albumin is - CORRECT ANSWER>>>>inactive
IV peak - CORRECT ANSWER>>>>30 min
oral peak - CORRECT ANSWER>>>>1 hour
pharmacokinetics - CORRECT ANSWER>>>>what the body does to the drug
pharmacodynamics - CORRECT ANSWER>>>>what the drug does to the body
1 tsp= ___ mL - CORRECT ANSWER>>>>5
1 tbs=___ tsp - CORRECT ANSWER>>>>3
1kg= ___ lb - CORRECT ANSWER>>>>2.2
, 9 rights of med admin - CORRECT ANSWER>>>>patient
drug
dose
time
route
reason
response
documentation
education
non opioid analgesics - CORRECT ANSWER>>>>acetaminophen, NSAIDs
acetaminophen - CORRECT ANSWER>>>>non opioid analgesic
acetaminophen ind - CORRECT ANSWER>>>>mild-mod pain, fever
acetaminophen does NOT help w - CORRECT ANSWER>>>>inflam
max dose acetaminophen/day - CORRECT ANSWER>>>>3000mg
acetaminophen contra - CORRECT ANSWER>>>>liver failure
acetaminophen interaction - CORRECT ANSWER>>>>caffeine enhances
acetaminophen adverse - CORRECT ANSWER>>>>toxic to liver
acetaminophen overdose causes - CORRECT ANSWER>>>>hepatotoxicity
acetaminophen antidote - CORRECT ANSWER>>>>NAC (N-Acetylcysteine)
acetaminophen NI - CORRECT ANSWER>>>>liver function tests: AST, ALT, bilirubin
NSAIDs - CORRECT ANSWER>>>>non opioid analgesics: aspirin, indomethacin, ketorolac,
ibuprophen, naproxen, celecoxib
NSAIDs ind - CORRECT ANSWER>>>>mild-mod pain, inflam, fever, aspirin-platelet
inhibition
NSAIDs contra - CORRECT ANSWER>>>>renal disease, GI bleeding
NSAIDs adverse - CORRECT ANSWER>>>>renal failure (toxic to kidneys), GI bleeding,
tinnitus, hearing loss, blurred vision
NSAIDs interactions - CORRECT ANSWER>>>>anticoagulants: high risk of bleeding
NSAIDs BBW - CORRECT ANSWER>>>>increased risk of cardio thrombotic events