1
NR 565 (GRADED A+)
MIDTERM EXAM: NR565/ NR 565 ADVANCED
PHARMACOLOGY CARE 2025 QUESTIONS AND CORRECT
ANSWERS ALREADY GRADED A+
Organic Nitrates Therapeutic Action
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation
Colchicine Adverse Effects
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis
Ezetimibe Use
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with
a statin or fibrate
Ezetimibe
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides
Lifestyle Changes for High Cholesterol
Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation
Minimizing Side Effects
, 2
NR 565 (GRADED A+)
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects
Gouty Arthritis Treatment Decision
In patients with infrequent flareups (less than three per year), NSAIDs are the first
line agent for relieving pain
Ranolazine Contraindications
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole
antifungal drugs, and some CCB
Statin Prescription Age
Avoid in children under 10
CCB Role in Variant Angina
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply
HF Worsening Symptoms Medication
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms
CCB Stable Angina
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand
NR 565 (GRADED A+)
MIDTERM EXAM: NR565/ NR 565 ADVANCED
PHARMACOLOGY CARE 2025 QUESTIONS AND CORRECT
ANSWERS ALREADY GRADED A+
Organic Nitrates Therapeutic Action
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation
Colchicine Adverse Effects
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis
Ezetimibe Use
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with
a statin or fibrate
Ezetimibe
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides
Lifestyle Changes for High Cholesterol
Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation
Minimizing Side Effects
, 2
NR 565 (GRADED A+)
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects
Gouty Arthritis Treatment Decision
In patients with infrequent flareups (less than three per year), NSAIDs are the first
line agent for relieving pain
Ranolazine Contraindications
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole
antifungal drugs, and some CCB
Statin Prescription Age
Avoid in children under 10
CCB Role in Variant Angina
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply
HF Worsening Symptoms Medication
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms
CCB Stable Angina
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand