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Medical Physiology and Pharmacology Exam
Questions And Answers 100% Pass
Which definition best describes a lead compound - ANS the first compound discovered to
have the desired activity
which method of discovering a drug is generally the least expensive - ANS molecular docking
what is the name of the process that involves step-wise alteration of a drug to improve its
properties - ANS structure activity relationship
what was the estimated research and development expenses of pharma in 2016 - ANS 60
billion
which branch of pharmacology studies the effect of the body on drugs -
ANS pharmacokinetics
which branch of pharmacology studies how patients respond differently to drugs -
ANS pharmacogenetics
which branch of pharmacology studies the desired effect of drugs on the body, usually at the
molecular level - ANS pharmacodynamics
which branch of pharmacology studies adverse effects of drugs on the body - ANS toxicology
, ©EVERLY 2025 ALL RIGHTS RESERVED
which branch of pharmacology does excretion fall under - ANS pharmacokinetics
which is the chemical name for a popular OTC pain killer - ANS N-acetyl-para-aminophenol
which stage of translational research is the first to utilize a FDA approved drug - ANS T3
the transition between which two phases of translational research involves switching from
controlled settings real-world setting - ANS T2-T3
which type of drug is most likely to be given orally - ANS small molecule
overnight contact lenses are considered ? medical devices - ANS class III
which term describes the process of taking a piece of humor tumor from a patient and placing it
under the skin of a mouse in order to do pre-clinical testing - ANS patient-derived xenograft
in order to do a clinical trial in humans, IRB approval must be obtained. From which regulatory
body must approval be obtained in order to carry out a similar study in rats? - ANS IACUC
gaining information on which of the following is the primary purpose of a Phase I clinical trial -
ANS treatment safety
which of the following requires direct action by a patient (or their guardian) before they can be
enrolled in a phase I clinical trial - ANS informed consent
in which type of clinical trial is a MTD most likely to be determined - ANS phase 1
, ©EVERLY 2025 ALL RIGHTS RESERVED
what government agency regulates phase I clinical trials in the US - ANS FDA
a clinical trial for the use of a new pain killer in terminal cancer patients who have been
admitted to hospice would be considered what type of clinical trial - ANS quality of life trial
how many groups of patients would be required for a placebo-controlled factorial trial to test
combinations of three drugs - ANS 8
in which type of clinical trial is every patient guaranteed to receive active drug - ANS cross-
over trial
exclusion criteria for a clinical trial for a new therapy for pediatric leukemia - ANS patient is
greater than 12 years old
the most common target of drugs is - ANS receptors
Gleevac targets - ANS enzymes
a diabetic receives an injection of insulin. Once the insulin reaches the pancreas, how long do
you expect it to take before a response can be measured - ANS minutes
a dose of agonist occupies 30% of receptors and gives an effect of 50. According to the
occupancy theory, what effect would you expect from a dose that occupies 90% of receptors -
ANS 150
most drugs bind in such a way that it is reversible without a chemical reaction. These drugs
must therefore lack which type of bond with their targets - ANS covalent
, ©EVERLY 2025 ALL RIGHTS RESERVED
drug A requires 15 micromolar to reach 50% of its maximum response while drug B requires 50
micromolar to reach 50% of its maximum response, which drug is more potent - ANS drug A
drug A requires 15 micromolar to reach 50% of its maximum response while drug B requires 50
micromolar to reach 50% of its maximum response, which drug is more effective -
ANS cannot tell
which term describes a molecule that produces an effect when binding a receptor but is
incapable of inducing 100% effect - ANS partial agonist
the addition of a competitive antagonist will affect the apparent ? of an agonist -
ANS potency
the addition of a non-competitive antagonist will affect the apparent ? of an agonist -
ANS efficacy
when drug A, an agonist, is given chronically, larger and larger concentrations are needed in
order to achieve the same effect. which phenomenon is likely occurring - ANS desensitization
which type of response curve would you look at if you wanted to know the exact response
predicted in a controlled system at a specified drug concentration - ANS graded
concentration response
when developing a new drug, do you generally want a high or low therapeutic index -
ANS high
aspirin has an ED50=5mg/dl and a TD50=100mg/dl what is the therapeutic index of aspirin -
ANS 20
Medical Physiology and Pharmacology Exam
Questions And Answers 100% Pass
Which definition best describes a lead compound - ANS the first compound discovered to
have the desired activity
which method of discovering a drug is generally the least expensive - ANS molecular docking
what is the name of the process that involves step-wise alteration of a drug to improve its
properties - ANS structure activity relationship
what was the estimated research and development expenses of pharma in 2016 - ANS 60
billion
which branch of pharmacology studies the effect of the body on drugs -
ANS pharmacokinetics
which branch of pharmacology studies how patients respond differently to drugs -
ANS pharmacogenetics
which branch of pharmacology studies the desired effect of drugs on the body, usually at the
molecular level - ANS pharmacodynamics
which branch of pharmacology studies adverse effects of drugs on the body - ANS toxicology
, ©EVERLY 2025 ALL RIGHTS RESERVED
which branch of pharmacology does excretion fall under - ANS pharmacokinetics
which is the chemical name for a popular OTC pain killer - ANS N-acetyl-para-aminophenol
which stage of translational research is the first to utilize a FDA approved drug - ANS T3
the transition between which two phases of translational research involves switching from
controlled settings real-world setting - ANS T2-T3
which type of drug is most likely to be given orally - ANS small molecule
overnight contact lenses are considered ? medical devices - ANS class III
which term describes the process of taking a piece of humor tumor from a patient and placing it
under the skin of a mouse in order to do pre-clinical testing - ANS patient-derived xenograft
in order to do a clinical trial in humans, IRB approval must be obtained. From which regulatory
body must approval be obtained in order to carry out a similar study in rats? - ANS IACUC
gaining information on which of the following is the primary purpose of a Phase I clinical trial -
ANS treatment safety
which of the following requires direct action by a patient (or their guardian) before they can be
enrolled in a phase I clinical trial - ANS informed consent
in which type of clinical trial is a MTD most likely to be determined - ANS phase 1
, ©EVERLY 2025 ALL RIGHTS RESERVED
what government agency regulates phase I clinical trials in the US - ANS FDA
a clinical trial for the use of a new pain killer in terminal cancer patients who have been
admitted to hospice would be considered what type of clinical trial - ANS quality of life trial
how many groups of patients would be required for a placebo-controlled factorial trial to test
combinations of three drugs - ANS 8
in which type of clinical trial is every patient guaranteed to receive active drug - ANS cross-
over trial
exclusion criteria for a clinical trial for a new therapy for pediatric leukemia - ANS patient is
greater than 12 years old
the most common target of drugs is - ANS receptors
Gleevac targets - ANS enzymes
a diabetic receives an injection of insulin. Once the insulin reaches the pancreas, how long do
you expect it to take before a response can be measured - ANS minutes
a dose of agonist occupies 30% of receptors and gives an effect of 50. According to the
occupancy theory, what effect would you expect from a dose that occupies 90% of receptors -
ANS 150
most drugs bind in such a way that it is reversible without a chemical reaction. These drugs
must therefore lack which type of bond with their targets - ANS covalent
, ©EVERLY 2025 ALL RIGHTS RESERVED
drug A requires 15 micromolar to reach 50% of its maximum response while drug B requires 50
micromolar to reach 50% of its maximum response, which drug is more potent - ANS drug A
drug A requires 15 micromolar to reach 50% of its maximum response while drug B requires 50
micromolar to reach 50% of its maximum response, which drug is more effective -
ANS cannot tell
which term describes a molecule that produces an effect when binding a receptor but is
incapable of inducing 100% effect - ANS partial agonist
the addition of a competitive antagonist will affect the apparent ? of an agonist -
ANS potency
the addition of a non-competitive antagonist will affect the apparent ? of an agonist -
ANS efficacy
when drug A, an agonist, is given chronically, larger and larger concentrations are needed in
order to achieve the same effect. which phenomenon is likely occurring - ANS desensitization
which type of response curve would you look at if you wanted to know the exact response
predicted in a controlled system at a specified drug concentration - ANS graded
concentration response
when developing a new drug, do you generally want a high or low therapeutic index -
ANS high
aspirin has an ED50=5mg/dl and a TD50=100mg/dl what is the therapeutic index of aspirin -
ANS 20
