2023-2024 HESI Pharmacology V1
Questions And Answers
A bnurse bis bcaring bfor ba bclient bwith bhyperparathyroidism band bnotes bthat bthe bclient's
bserum bcalcium blevel bis b13 bmg/dL. bWhich bmedication bshould bthe bnurse bprepare bto
badminister bas bprescribed bto bthe bclient?1. bCalcium bchloride
2. bCalcium bgluconate
3. bCalcitonin b(Miacalcin)
4. bLarge bdoses bof bvitamin bD b- bcorrect banswers✔✔3. bCalcitonin b(Miacalcin)
Rationale: b
The bnormal bserum bcalcium blevel bis b8.6 bto b10.0 bmg/dL. bThis bclient bis bexperiencing
bhypercalcemia. bCalcium bgluconate band bcalcium bchloride bare bmedications bused bfor
bthe btreatment bof btetany, bwhich boccurs bas ba bresult bof bacute bhypocalcemia. bIn
bhypercalcemia, blarge bdoses bof bvitamin bD bneed bto bbe bavoided. bCalcitonin, ba
bthyroid bhormone, bdecreases bthe bplasma bcalcium blevel bby binhibiting bbone
bresorption band blowering bthe bserum bcalcium bconcentration.
Oral biron bsupplements bare bprescribed bfor ba b6-year-old bchild bwith biron bdeficiency
banemia. bThe bnurse binstructs bthe bmother bto badminister bthe biron bwith bwhich bbest
bfood bitem?
1. bMilk
2. bWater
3. bApple bjuice
4. bOrange bjuice b- bcorrect banswers✔✔4. bOrange bjuice
Rationale: b
Vitamin bC bincreases bthe babsorption bof biron bby bthe bbody. bThe bmother bshould bbe
binstructed bto badminister bthe bmedication bwith ba bcitrus bfruit bor ba bjuice bthat bis bhigh
bin bvitamin bC. bMilk bmay baffect babsorption bof bthe biron. bWater bwill bnot bassist bin
babsorption. bOrange bjuice bcontains ba bgreater bamount bof bvitamin bC bthan bapple
bjuice.
Salicylic bacid bis bprescribed bfor ba bclient bwith ba bdiagnosis bof bpsoriasis. bThe bnurse
bmonitors bthe bclient, bknowing bthat bwhich bof bthe bfollowing bwould bindicate bthe
bpresence bof bsystemic btoxicity bfrom bthis bmedication?
,1. bTinnitus
2. bDiarrhea b
3. bConstipation b
4. bDecreased bRespirations b- bcorrect banswers✔✔1. bTinnitus
Rationale: b
Salicylic bacid bis babsorbed breadily bthrough bthe bskin, band bsystemic btoxicity
b(salicylism) bcan bresult. bSymptoms binclude btinnitus, bdizziness, bhyperpnea, band
bpsychological bdisturbances. bConstipation band bdiarrhea bare bnot bassociated bwith
bsalicylism.
The bcamp bnurse basks bthe bchildren bpreparing bto bswim bin bthe blake bif bthey bhave
bapplied bsunscreen. bThe bnurse breminds bthe bchildren bthat bchemical bsunscreens bare
bmost beffective bwhen bapplied:
1. bImmediately bbefore bswimming
2. b15 bminutes bbefore bexposure bto bthe bsun
3. bImmediately bbefore bexposure bto bthe bsun
4. bAt bleast b30 bminutes bbefore bexposure bto bthe bsun b- bcorrect banswers✔✔4. bAt
bleast b30 bminutes bbefore bexposure bto bthe bsun
Rationale: b
Sunscreens bare bmost beffective bwhen bapplied bat bleast b30 bminutes bbefore bexposure
bto bthe bsun bso bthat bthey bcan bpenetrate bthe bskin. bAll bsunscreens bshould bbe
breapplied bafter bswimming bor bsweating
Mafenide bacetate b(Sulfamylon) bis bprescribed bfor bthe bclient bwith ba bburn binjury.
bWhen bapplying bthe bmedication, bthe bclient bcomplains bof blocal bdiscomfort band
bburning. bWhich bof bthe bfollowing bis bthe bmost bappropriate bnursing baction?
1. bNotifying bthe bregistered bnurse
2. bDiscontinuing bthe bmedication
3. bInforming bthe bclient bthat bthis bis bnormal
4. bApplying ba bthinner bfilm bthan bprescribed bto bthe bburn bsite b- bcorrect
banswers✔✔3. bInforming bthe bclient bthat bthis bis bnormal
Rationale: b
Mafenide bacetate bis bbacteriostatic bfor bgram-negative band bgram-positive borganisms
band bis bused bto btreat bburns bto breduce bbacteria bpresent bin bavascular btissues. bThe
bclient bshould bbe binformed bthat bthe bmedication bwill bcause blocal bdiscomfort band
bburning band bthat bthis bis ba bnormal breaction; btherefore boptions b1, b2, band b4 bare
bincorrect
The bburn bclient bis breceiving btreatments bof btopical bmafenide bacetate b(Sulfamylon)
bto bthe bsite bof binjury. bThe bnurse bmonitors bthe bclient, bknowing bthat bwhich bof bthe
bfollowing bindicates bthat ba bsystemic beffect bhas boccurred?1.Hyperventilation
2.Elevated bblood bpressure b
3.Local bpain bat bthe bburn bsite b
,4.Local brash bat bthe bburn bsite b- bcorrect banswers✔✔1.Hyperventilation
Rationale: b
Mafenide bacetate bis ba bcarbonic banhydrase binhibitor band bcan bsuppress brenal
bexcretion bof bacid, bthereby bcausing bacidosis. bClients breceiving bthis btreatment
bshould bbe bmonitored bfor bsigns bof ban bacid-base bimbalance b(hyperventilation). bIf
bthis boccurs, bthe bmedication bshould bbe bdiscontinued bfor b1 bto b2 bdays. bOptions b3
band b4 bdescribe blocal brather bthan bsyeffects. bAn belevated bblood bpressure bmay bbe
bexpected bfrom bthe bpain bthat boccurs bwith ba bburn binjury.
Isotretinoin bis bprescribed bfor ba bclient bwith bsevere bacne. bBefore bthe badministration
bof bthis bmedication, bthe bnurse banticipates bthat bwhich blaboratory btest bwill bbe
bprescribed?
1. bPlatelet bcount
2. bTriglyceride blevel
3. bComplete bblood bcount b
4. bWhite bblood bcell bcount b- bcorrect banswers✔✔2. bTriglyceride blevel
Rationale: b
Isotretinoin bcan belevate btriglyceride blevels. bBlood btriglyceride blevels bshould bbe
bmeasured bbefore btreatment band bperiodically bthereafter buntil bthe beffect bon bthe
btriglycerides bhas bbeen bevaluated. bOptions b1, b3, band b4 bdo bnot bneed bto bbe
bmonitored bspecifically bduring bthis btreatment.
A bclient bwith bsevere bacne bis bseen bin bthe bclinic band bthe bhealth bcare bprovider
b(HCP) bprescribes bisotretinoin. bThe bnurse breviews bthe bclient's bmedication brecord
band bwould bcontact bthe b(HCP) bif bthe bclient bis btaking bwhich bmedication?
1. bVitamin bA
2. bDigoxin b(Lanoxin) b
3. bFurosemide b(Lasix) b
4. bPhenytoin b(Dilantin) b- bcorrect banswers✔✔1. bVitamin bA
Rationale: b
Isotretinoin bis ba bmetabolite bof bvitamin bA band bcan bproduce bgeneralized
bintensification bof bisotretinoin btoxicity. bBecause bof bthe bpotential bfor bincreased
btoxicity, bvitamin bA bsupplements bshould bbe bdiscontinued bbefore bisotretinoin
btherapy. bOptions b2, b3, band b4 bare bnot bcontraindicated bwith bthe buse bof bisotretinoin
The bnurse bis bapplying ba btopical bcorticosteroid bto ba bclient bwith beczema. bThe bnurse
bwould bmonitor bfor bthe bpotential bfor bincreased bsystemic babsorption bof bthe
bmedication bif bthe bmedication bwere bbeing bapplied bto bwhich bof bthe bfollowing bbody
bareas?
1. bBack
2. bAxilla
3. bSoles bof bthe bfeet
4. bPalms bof bthe bhands b- bcorrect banswers✔✔2. bAxilla
, Rationale: b
Topical bcorticosteroids bcan bbe babsorbed binto bthe bsystemic bcirculation. bAbsorption
bis bhigher bfrom bregions bwhere bthe bskin bis bespecially bpermeable b(scalp, baxilla,
bface, beyelids, bneck, bperineum, bgenitalia), band blower bfrom bregions bin bwhich
bpermeability bis bpoor b(back, bpalms, bsoles).
The bclinic bnurse bis bperforming ban badmission bassessment bon ba bclient. bThe bnurse
bnotes bthat bthe bclient bis btaking bazelaic bacid b(Azelex). bBecause bof bthe bmedication
bprescription, bthe bnurse bwould bsuspect bthat bthe bclient bis bbeing btreated bfor:
1. bAcne
2. bEczema
3. bHair bloss
4. bHerpes bsimplex b- bcorrect banswers✔✔1. bAcne
Rationale: b
Azelaic bacid bis ba btopical bmedication bused bto btreat bmild bto bmoderate bacne. bThe
bacid bappears bto bwork bby bsuppressing bthe bgrowth bof bPropionibacterium bacnes band
bdecreasing bthe bproliferation bof bkeratinocytes. bOptions b2, b3, band b4 bare bincorrect.
The bhealth bcare bprovider bhas bprescribed bsilver bsulfadiazine b(Silvadene) bfor bthe
bclient bwith ba bpartial-thickness bburn, bwhich bhas bcultured bpositive bfor bgram-negative
bbacteria. bThe bnurse bis breinforcing binformation bto bthe bclient babout bthe bmedication.
bWhich bstatement bmade bby bthe bclient bindicates ba black bof bunderstanding babout bthe
btreatments?
1. b"The bmedication bis ban bantibacterial."
2. b"The bmedication bwill bhelp bheal bthe bburn."
3. b"The bmedication bwill bpermanently bstain bmy bskin."
4. b"The bmedication bshould bbe bapplied bdirectly bto bthe bwound." b- bcorrect
banswers✔✔3. b"The bmedication bwill bpermanently bstain bmy bskin."
Rationale: b
Silver bsulfadiazine b(Silvadene) bis ban bantibacterial bthat bhas ba bbroad bspectrum bof
bactivity bagainst bgram-negative bbacteria, bgram-positive bbacteria, band byeast. bIt bis
bapplied bdirectly bto bthe bwound bto bassist bin bhealing. bIt bdoes bnot bstain bthe bskin.
A bnurse bis bcaring bfor ba bclient bwho bis breceiving ban bintravenous b(IV) binfusion bof ban
bantineoplastic bmedication. bDuring bthe binfusion, bthe bclient bcomplains bof bpain bat bthe
binsertion bsite. bDuring ban binspection bof bthe bsite, bthe bnurse bnotes bredness band
bswelling band bthat bthe brate bof binfusion bof bthe bmedication bhas bslowed. bThe bnurse
bshould btake bwhich bappropriate baction?
1. bNotify bthe bregistered bnurse.
2. bAdminister bpain bmedication bto breduce bthe bdiscomfort.
3. bApply bice band bmaintain bthe binfusion brate, bas bprescribed. b
4. bElevate bthe bextremity bof bthe bIV bsite, band bslow bthe binfusion b- bcorrect
banswers✔✔1. bNotify bthe bregistered bnurse.
Questions And Answers
A bnurse bis bcaring bfor ba bclient bwith bhyperparathyroidism band bnotes bthat bthe bclient's
bserum bcalcium blevel bis b13 bmg/dL. bWhich bmedication bshould bthe bnurse bprepare bto
badminister bas bprescribed bto bthe bclient?1. bCalcium bchloride
2. bCalcium bgluconate
3. bCalcitonin b(Miacalcin)
4. bLarge bdoses bof bvitamin bD b- bcorrect banswers✔✔3. bCalcitonin b(Miacalcin)
Rationale: b
The bnormal bserum bcalcium blevel bis b8.6 bto b10.0 bmg/dL. bThis bclient bis bexperiencing
bhypercalcemia. bCalcium bgluconate band bcalcium bchloride bare bmedications bused bfor
bthe btreatment bof btetany, bwhich boccurs bas ba bresult bof bacute bhypocalcemia. bIn
bhypercalcemia, blarge bdoses bof bvitamin bD bneed bto bbe bavoided. bCalcitonin, ba
bthyroid bhormone, bdecreases bthe bplasma bcalcium blevel bby binhibiting bbone
bresorption band blowering bthe bserum bcalcium bconcentration.
Oral biron bsupplements bare bprescribed bfor ba b6-year-old bchild bwith biron bdeficiency
banemia. bThe bnurse binstructs bthe bmother bto badminister bthe biron bwith bwhich bbest
bfood bitem?
1. bMilk
2. bWater
3. bApple bjuice
4. bOrange bjuice b- bcorrect banswers✔✔4. bOrange bjuice
Rationale: b
Vitamin bC bincreases bthe babsorption bof biron bby bthe bbody. bThe bmother bshould bbe
binstructed bto badminister bthe bmedication bwith ba bcitrus bfruit bor ba bjuice bthat bis bhigh
bin bvitamin bC. bMilk bmay baffect babsorption bof bthe biron. bWater bwill bnot bassist bin
babsorption. bOrange bjuice bcontains ba bgreater bamount bof bvitamin bC bthan bapple
bjuice.
Salicylic bacid bis bprescribed bfor ba bclient bwith ba bdiagnosis bof bpsoriasis. bThe bnurse
bmonitors bthe bclient, bknowing bthat bwhich bof bthe bfollowing bwould bindicate bthe
bpresence bof bsystemic btoxicity bfrom bthis bmedication?
,1. bTinnitus
2. bDiarrhea b
3. bConstipation b
4. bDecreased bRespirations b- bcorrect banswers✔✔1. bTinnitus
Rationale: b
Salicylic bacid bis babsorbed breadily bthrough bthe bskin, band bsystemic btoxicity
b(salicylism) bcan bresult. bSymptoms binclude btinnitus, bdizziness, bhyperpnea, band
bpsychological bdisturbances. bConstipation band bdiarrhea bare bnot bassociated bwith
bsalicylism.
The bcamp bnurse basks bthe bchildren bpreparing bto bswim bin bthe blake bif bthey bhave
bapplied bsunscreen. bThe bnurse breminds bthe bchildren bthat bchemical bsunscreens bare
bmost beffective bwhen bapplied:
1. bImmediately bbefore bswimming
2. b15 bminutes bbefore bexposure bto bthe bsun
3. bImmediately bbefore bexposure bto bthe bsun
4. bAt bleast b30 bminutes bbefore bexposure bto bthe bsun b- bcorrect banswers✔✔4. bAt
bleast b30 bminutes bbefore bexposure bto bthe bsun
Rationale: b
Sunscreens bare bmost beffective bwhen bapplied bat bleast b30 bminutes bbefore bexposure
bto bthe bsun bso bthat bthey bcan bpenetrate bthe bskin. bAll bsunscreens bshould bbe
breapplied bafter bswimming bor bsweating
Mafenide bacetate b(Sulfamylon) bis bprescribed bfor bthe bclient bwith ba bburn binjury.
bWhen bapplying bthe bmedication, bthe bclient bcomplains bof blocal bdiscomfort band
bburning. bWhich bof bthe bfollowing bis bthe bmost bappropriate bnursing baction?
1. bNotifying bthe bregistered bnurse
2. bDiscontinuing bthe bmedication
3. bInforming bthe bclient bthat bthis bis bnormal
4. bApplying ba bthinner bfilm bthan bprescribed bto bthe bburn bsite b- bcorrect
banswers✔✔3. bInforming bthe bclient bthat bthis bis bnormal
Rationale: b
Mafenide bacetate bis bbacteriostatic bfor bgram-negative band bgram-positive borganisms
band bis bused bto btreat bburns bto breduce bbacteria bpresent bin bavascular btissues. bThe
bclient bshould bbe binformed bthat bthe bmedication bwill bcause blocal bdiscomfort band
bburning band bthat bthis bis ba bnormal breaction; btherefore boptions b1, b2, band b4 bare
bincorrect
The bburn bclient bis breceiving btreatments bof btopical bmafenide bacetate b(Sulfamylon)
bto bthe bsite bof binjury. bThe bnurse bmonitors bthe bclient, bknowing bthat bwhich bof bthe
bfollowing bindicates bthat ba bsystemic beffect bhas boccurred?1.Hyperventilation
2.Elevated bblood bpressure b
3.Local bpain bat bthe bburn bsite b
,4.Local brash bat bthe bburn bsite b- bcorrect banswers✔✔1.Hyperventilation
Rationale: b
Mafenide bacetate bis ba bcarbonic banhydrase binhibitor band bcan bsuppress brenal
bexcretion bof bacid, bthereby bcausing bacidosis. bClients breceiving bthis btreatment
bshould bbe bmonitored bfor bsigns bof ban bacid-base bimbalance b(hyperventilation). bIf
bthis boccurs, bthe bmedication bshould bbe bdiscontinued bfor b1 bto b2 bdays. bOptions b3
band b4 bdescribe blocal brather bthan bsyeffects. bAn belevated bblood bpressure bmay bbe
bexpected bfrom bthe bpain bthat boccurs bwith ba bburn binjury.
Isotretinoin bis bprescribed bfor ba bclient bwith bsevere bacne. bBefore bthe badministration
bof bthis bmedication, bthe bnurse banticipates bthat bwhich blaboratory btest bwill bbe
bprescribed?
1. bPlatelet bcount
2. bTriglyceride blevel
3. bComplete bblood bcount b
4. bWhite bblood bcell bcount b- bcorrect banswers✔✔2. bTriglyceride blevel
Rationale: b
Isotretinoin bcan belevate btriglyceride blevels. bBlood btriglyceride blevels bshould bbe
bmeasured bbefore btreatment band bperiodically bthereafter buntil bthe beffect bon bthe
btriglycerides bhas bbeen bevaluated. bOptions b1, b3, band b4 bdo bnot bneed bto bbe
bmonitored bspecifically bduring bthis btreatment.
A bclient bwith bsevere bacne bis bseen bin bthe bclinic band bthe bhealth bcare bprovider
b(HCP) bprescribes bisotretinoin. bThe bnurse breviews bthe bclient's bmedication brecord
band bwould bcontact bthe b(HCP) bif bthe bclient bis btaking bwhich bmedication?
1. bVitamin bA
2. bDigoxin b(Lanoxin) b
3. bFurosemide b(Lasix) b
4. bPhenytoin b(Dilantin) b- bcorrect banswers✔✔1. bVitamin bA
Rationale: b
Isotretinoin bis ba bmetabolite bof bvitamin bA band bcan bproduce bgeneralized
bintensification bof bisotretinoin btoxicity. bBecause bof bthe bpotential bfor bincreased
btoxicity, bvitamin bA bsupplements bshould bbe bdiscontinued bbefore bisotretinoin
btherapy. bOptions b2, b3, band b4 bare bnot bcontraindicated bwith bthe buse bof bisotretinoin
The bnurse bis bapplying ba btopical bcorticosteroid bto ba bclient bwith beczema. bThe bnurse
bwould bmonitor bfor bthe bpotential bfor bincreased bsystemic babsorption bof bthe
bmedication bif bthe bmedication bwere bbeing bapplied bto bwhich bof bthe bfollowing bbody
bareas?
1. bBack
2. bAxilla
3. bSoles bof bthe bfeet
4. bPalms bof bthe bhands b- bcorrect banswers✔✔2. bAxilla
, Rationale: b
Topical bcorticosteroids bcan bbe babsorbed binto bthe bsystemic bcirculation. bAbsorption
bis bhigher bfrom bregions bwhere bthe bskin bis bespecially bpermeable b(scalp, baxilla,
bface, beyelids, bneck, bperineum, bgenitalia), band blower bfrom bregions bin bwhich
bpermeability bis bpoor b(back, bpalms, bsoles).
The bclinic bnurse bis bperforming ban badmission bassessment bon ba bclient. bThe bnurse
bnotes bthat bthe bclient bis btaking bazelaic bacid b(Azelex). bBecause bof bthe bmedication
bprescription, bthe bnurse bwould bsuspect bthat bthe bclient bis bbeing btreated bfor:
1. bAcne
2. bEczema
3. bHair bloss
4. bHerpes bsimplex b- bcorrect banswers✔✔1. bAcne
Rationale: b
Azelaic bacid bis ba btopical bmedication bused bto btreat bmild bto bmoderate bacne. bThe
bacid bappears bto bwork bby bsuppressing bthe bgrowth bof bPropionibacterium bacnes band
bdecreasing bthe bproliferation bof bkeratinocytes. bOptions b2, b3, band b4 bare bincorrect.
The bhealth bcare bprovider bhas bprescribed bsilver bsulfadiazine b(Silvadene) bfor bthe
bclient bwith ba bpartial-thickness bburn, bwhich bhas bcultured bpositive bfor bgram-negative
bbacteria. bThe bnurse bis breinforcing binformation bto bthe bclient babout bthe bmedication.
bWhich bstatement bmade bby bthe bclient bindicates ba black bof bunderstanding babout bthe
btreatments?
1. b"The bmedication bis ban bantibacterial."
2. b"The bmedication bwill bhelp bheal bthe bburn."
3. b"The bmedication bwill bpermanently bstain bmy bskin."
4. b"The bmedication bshould bbe bapplied bdirectly bto bthe bwound." b- bcorrect
banswers✔✔3. b"The bmedication bwill bpermanently bstain bmy bskin."
Rationale: b
Silver bsulfadiazine b(Silvadene) bis ban bantibacterial bthat bhas ba bbroad bspectrum bof
bactivity bagainst bgram-negative bbacteria, bgram-positive bbacteria, band byeast. bIt bis
bapplied bdirectly bto bthe bwound bto bassist bin bhealing. bIt bdoes bnot bstain bthe bskin.
A bnurse bis bcaring bfor ba bclient bwho bis breceiving ban bintravenous b(IV) binfusion bof ban
bantineoplastic bmedication. bDuring bthe binfusion, bthe bclient bcomplains bof bpain bat bthe
binsertion bsite. bDuring ban binspection bof bthe bsite, bthe bnurse bnotes bredness band
bswelling band bthat bthe brate bof binfusion bof bthe bmedication bhas bslowed. bThe bnurse
bshould btake bwhich bappropriate baction?
1. bNotify bthe bregistered bnurse.
2. bAdminister bpain bmedication bto breduce bthe bdiscomfort.
3. bApply bice band bmaintain bthe binfusion brate, bas bprescribed. b
4. bElevate bthe bextremity bof bthe bIV bsite, band bslow bthe binfusion b- bcorrect
banswers✔✔1. bNotify bthe bregistered bnurse.
