2024 Hesi Pharmacology Version A
Latest Version 2024 Questions And
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The bhealth bcare bprovider bprescribes bcarbamazepine bfor ba bchild bwhose btonic-clonic
bseizures bhave bbeen bpoorly bcontrolled. bThe bnurse binforms bthe bmother bthat bthe
bchild bmust bhave bblood btests bevery bweek. bThe bmother basks bwhy bso bmany bblood
btests bare bnecessary. bWhich bcomplication bis bassessed bthrough bfrequent blaboratory
btesting bthat bthe bnurse bshould bexplain bto bthis bmother? b- bcorrect
banswers✔✔Myelosuppression b
Rationale: bMyelosuppression bisthe bhighest bpriority bcomplication bthat bcan bpotentially
baffect bclients bmanaged bwith bcarbamazepine btherapy. bThe bclient brequires bclose
bmonitoring bfor bthis bcondition bby bweekly blaboratory btesting. bHepatic bfunction bmay
bbe baltered, bbut bthis bcomplication bdoes bnot bhave bas bgreat ba bpotential bfor
boccurrence bas bMyelosupression
A bclient bis bprescribed ba bcholinesterase binhibitor, band ba bfamily bmember basks bthe
bnurse bhow bthis bmedication bworks. bWhich bpharmacophysiologic bexplanation bshould
bthe bnurse buse bto bdescribe bthis bclass bof bdrug? b- bcorrect banswers✔✔Improves
bnerve bimpulse btransmission b
Rationale: bCholinesterase binhibitors bwork bto bincrease bthe bavailability bof
bacetylcholine bat bcholinergic bsynapses, bwhich baids bin bneuronal btransmission band
bassists bin bmemory bformation.
A bclient bis bordered b22 bmg bof bgentamicin bby bIM binjection. bThe bdrug bis bavailable
bin b20 bmg/2 bmL. bHow bmany bmilliliters bshould bbe badministered? b- bcorrect
banswers✔✔2.2 bmL b
Rationale: b(22 bmg/20 bmg) b× b(x bmL/2 bmL) b= b22x b= b40 bx b= b2.2 bmL
In baddition bto bnitrate btherapy, ba bclient bis breceiving bnifedipine, b10 bmg bPO bevery b6
bhours. bThe bnurse bshould bplan bto bobserve bfor bwhich bcommon bside beffect bof bthis
btreatment bregimen? b- bcorrect banswers✔✔Hypotension b
,Rationale: bNifedipine breduces bperipheral bvascular bresistance band bnitrates bproduce
bvasodilation,so bconcurrent buse bof bnitrates bwith bnifedipine bcan bcause bhypotension
bwith bthe binitial badministration bof bthese bagents.
Which bresponse bbest bsupports bthe bobservations bthat bthe bnurse bidentifies bin ba
bclient bwho bis bexperiencing ba bplacebo beffect? b- bcorrect banswers✔✔Psychological
bresponse bto binert bmedication b
Rationale: bThe bplacebo beffect bis ba bresponse bin bthe bclient bthat bis bcaused bby bthe
bpsychological bimpact bof btaking ban binert bdrug bthat bhas bno bbiochemical bproperties.
bA bplacebo beffect bcan bbe btherapeutic, bnegative, bor bineffective bbut bprovides bno
bcure bor bbenefit bto bthe bclient's bprogress. bThe bplacebo beffect bmay bevoke
bbehavioral bchanges bbut bdoes bnot baffect bneurochemical bpsychotropic bchanges.
bMalingering band bdrug bseeking bare bbehaviors bthat ba bclient bexhibits bto bobtain
btreatment bfor bnonexistent bdisorders bor bobtain bprescription bmedications.
A b42-year-old bclient bis badmitted bto bthe bemergency bdepartment bafter btaking ban
boverdose bof bamitriptyline bin ba bsuicide battempt. bWhich bdrug bshould bthe bnurse bplan
bto badminister bto breverse bthe bcardiac band bcentral bnervous bsystem beffects bof
bamitriptyline? b- bcorrect banswers✔✔Sodium bbicarbonate b
Rationale: bSodium bbicarbonate bis ban beffective btreatment bfor ban boverdose bof
btricyclic bantidepressantssuch bas bamitriptyline bto breverse bQRS bprolongation.
A b67-year-old bclient bis bdischarged bfrom bthe bhospital bwith ba bprescription bfor
bdigoxin, b0.25 bmg bdaily. bWhich binstruction bshould bthe bnurse binclude bin bthis bclient's
bdischarge bteaching bplan? b- bcorrect banswers✔✔Take band brecord bradial bpulse brate
bdaily. b
Rationale: bMonitoring bpulse brate bis bvery bimportant bwhen btaking bdigoxin. bThe bclient
bshould bbe bfurther binstructed bto breport bpulse brates b<60 bor b>110 bbeats/min band bto
bwithhold bthe bdosage buntil bconsulting bwith bthe bhealth bcare bprovider bin bsuch ba
bcase. bVision bchange bis ban bindication bof bdrug btoxicity, band bthe bclient bshould bbe
binstructed bto breport bthis bimmediately.
A b55-year-old bclient bwas bdiagnosed bwith bschizophrenia b5 byears bearlier. bNumerous
bhospitalizations bhave boccurred bsince bthe bdiagnosis bbecause bof bnoncompliance
bwith bthe bprescribed bmedication bregimen. bWhich bdrug bmight bwork bbest bfor bthis
bparticular bclient? b- bcorrect banswers✔✔Fluphenazine bdecanoate b
Rationale: bFluphenazine, ban bantipsychotic bdrug bthat bcan bbe bgiven bIM, bhas ba brapid
bonset b(1 bto b2 bhours) band ba blong bduration bof baction b(up bto b3 bor b4 bweeks), bso bit
bwould bbe bthe bdrug bof bchoice bfor ba bnoncompliant bpsychotic bclient. bChlorpromazine
bHCl bis ban bantipsychotic bdrug bused bto btreat bschizophrenia band bis busually
badministered bPO b(IM bdoses bare bshort-acting). bThe bclient bmust bbe bcompliant bin
btaking bthis bdrug bfor bit bto bbe beffective. bLithium bcarbonate bis bmost beffective bwith
bmanic band bdepressive bbipolar baffective bdisorders. bDiazepam bis ban banti-anxiety
bdrug band bwould bnot bbe beffective bfor ba bpsychotic bdisorder.
, A bclient bis bbeing bdischarged bwith ba bprescription bfor bsulfasalazine bto btreat
bulcerative bcolitis. bWhich binstruction bshould bthe bnurse bprovide bto bthis bclient bprior
bto bdischarge? b- bcorrect banswers✔✔Drink bat bleast beight bglasses bof bfluid ba bday b
Rationale: bAdequate bhydration bis bimportant bfor ball bsulfa bdrugs bbecause bthey bcan
bcrystallize bin bthe burine. bIf bpossible, bthe bdrug bshould bbe btaken bafter beating bto
bprovide blonger bintestinal btransit btime. bMaintaining bgood boral bhygiene bis bimportant
bfor bother bmedications, bsuch bas bphenytoin, bbecause bof bthe bincidence bof bgingival
bhyperplasia, bDiscontinue buse bof bthe bdrug bgradually bis bimportant bfor bsteroid
badministration.
Amoxicillin, b500 bmg bPO bevery b8 bhours, bis bprescribed bfor ba bclient bwith ban
binfection. bThe bdrug bis bavailable bin ba bsuspension bof b125 bmg/5 bmL. bHow bmany
bmilliliters bshould bthe bnurse badminister bwith beach bdose? b- bcorrect banswers✔✔20
bmL b
Rationale: b500 bmg/x bmL b= b125 bmg/5 bmL b125x b= b2500 bx b= b20 bmL
A bclient bwith bacute blymphocytic bleukemia bisto bbegin bchemotherapy btoday. bThe
bhealth bcare bprovider's bprescription bspecifies bthat bondansetron bis bto bbe
badministered bIV b30 bminutes bprior bto bthe binfusion bof bcisplatin. bWhat bis bthe
brationale bfor badministering bZofran bprior bto bthe bchemotherapy binduction? b- bcorrect
banswers✔✔Reduction bor belimination bof bnausea band bvomiting b
Rationale: bOndansetron bis ba btype b3 breceptor b(5-HT3) bantagonist bthat bisrecognized
bfor bimproved bcontrol bof bacute bnausea band bvomiting bassociated bwith
bchemotherapy. b5-HT3 bantagonists bare bmost beffective bwhen badministered bIV bprior
bto bthe binduction bof bthe bchemotherapeutic bagent(s).
A bclient bwith bchronic bgouty barthritis bis btalking ballopurinol, b100 bmg bPO bdaily.
bWhich blaboratory bserum blevel bshould bthe bnurse breport bto bthe bhealth bcare
bprovider bto bdetermine bthe btherapeutic boutcome? b- bcorrect banswers✔✔Uric bacid
blevel b
Rationale: bThe bprimary btherapeutic boutcome bassociated bwith ballopurinol btherapy bis
breduced bserum buric bacid blevels bwith ba blower bfrequency bof bacute bgouty battacks,
bso buric bacid blevel bshould bbe breported bto bthe bhealth bcare bprovider
The bnurse bis breviewing bprescribed bmedications bwith ba bfemale bclient bwho bis
bpreparing bfor bdischarge. bThe bclient basks bthe bnurse bwhy bthe boral bdose bof ban
bopioid banalgesic bis bhigher bthan bthe bIV bdose bthat bshe breceived bduring
bhospitalization. bWhich bresponse bis bbest bfor bthe bnurse bto bprovide? b- bcorrect
banswers✔✔Oral bforms bof bdrugs bmust bpass bthrough bthe bliver bfirst, bwhere bmore bof
bthe bdose bis bmetabolized. b
Rationale: bOral bdoses bof bmedication bare busually blarger bthan bparenteral bdosesto
bcompensate bfor bthe bfirst-pass beffect bin bthe bliver bafter boral badministration, bwhich
bmetabolizes bmore bof bthe bdrug's bdose bbefore baffecting bits btherapeutic bresponse.
Latest Version 2024 Questions And
Correct Answers(Detailed Answers)|
Agrade
The bhealth bcare bprovider bprescribes bcarbamazepine bfor ba bchild bwhose btonic-clonic
bseizures bhave bbeen bpoorly bcontrolled. bThe bnurse binforms bthe bmother bthat bthe
bchild bmust bhave bblood btests bevery bweek. bThe bmother basks bwhy bso bmany bblood
btests bare bnecessary. bWhich bcomplication bis bassessed bthrough bfrequent blaboratory
btesting bthat bthe bnurse bshould bexplain bto bthis bmother? b- bcorrect
banswers✔✔Myelosuppression b
Rationale: bMyelosuppression bisthe bhighest bpriority bcomplication bthat bcan bpotentially
baffect bclients bmanaged bwith bcarbamazepine btherapy. bThe bclient brequires bclose
bmonitoring bfor bthis bcondition bby bweekly blaboratory btesting. bHepatic bfunction bmay
bbe baltered, bbut bthis bcomplication bdoes bnot bhave bas bgreat ba bpotential bfor
boccurrence bas bMyelosupression
A bclient bis bprescribed ba bcholinesterase binhibitor, band ba bfamily bmember basks bthe
bnurse bhow bthis bmedication bworks. bWhich bpharmacophysiologic bexplanation bshould
bthe bnurse buse bto bdescribe bthis bclass bof bdrug? b- bcorrect banswers✔✔Improves
bnerve bimpulse btransmission b
Rationale: bCholinesterase binhibitors bwork bto bincrease bthe bavailability bof
bacetylcholine bat bcholinergic bsynapses, bwhich baids bin bneuronal btransmission band
bassists bin bmemory bformation.
A bclient bis bordered b22 bmg bof bgentamicin bby bIM binjection. bThe bdrug bis bavailable
bin b20 bmg/2 bmL. bHow bmany bmilliliters bshould bbe badministered? b- bcorrect
banswers✔✔2.2 bmL b
Rationale: b(22 bmg/20 bmg) b× b(x bmL/2 bmL) b= b22x b= b40 bx b= b2.2 bmL
In baddition bto bnitrate btherapy, ba bclient bis breceiving bnifedipine, b10 bmg bPO bevery b6
bhours. bThe bnurse bshould bplan bto bobserve bfor bwhich bcommon bside beffect bof bthis
btreatment bregimen? b- bcorrect banswers✔✔Hypotension b
,Rationale: bNifedipine breduces bperipheral bvascular bresistance band bnitrates bproduce
bvasodilation,so bconcurrent buse bof bnitrates bwith bnifedipine bcan bcause bhypotension
bwith bthe binitial badministration bof bthese bagents.
Which bresponse bbest bsupports bthe bobservations bthat bthe bnurse bidentifies bin ba
bclient bwho bis bexperiencing ba bplacebo beffect? b- bcorrect banswers✔✔Psychological
bresponse bto binert bmedication b
Rationale: bThe bplacebo beffect bis ba bresponse bin bthe bclient bthat bis bcaused bby bthe
bpsychological bimpact bof btaking ban binert bdrug bthat bhas bno bbiochemical bproperties.
bA bplacebo beffect bcan bbe btherapeutic, bnegative, bor bineffective bbut bprovides bno
bcure bor bbenefit bto bthe bclient's bprogress. bThe bplacebo beffect bmay bevoke
bbehavioral bchanges bbut bdoes bnot baffect bneurochemical bpsychotropic bchanges.
bMalingering band bdrug bseeking bare bbehaviors bthat ba bclient bexhibits bto bobtain
btreatment bfor bnonexistent bdisorders bor bobtain bprescription bmedications.
A b42-year-old bclient bis badmitted bto bthe bemergency bdepartment bafter btaking ban
boverdose bof bamitriptyline bin ba bsuicide battempt. bWhich bdrug bshould bthe bnurse bplan
bto badminister bto breverse bthe bcardiac band bcentral bnervous bsystem beffects bof
bamitriptyline? b- bcorrect banswers✔✔Sodium bbicarbonate b
Rationale: bSodium bbicarbonate bis ban beffective btreatment bfor ban boverdose bof
btricyclic bantidepressantssuch bas bamitriptyline bto breverse bQRS bprolongation.
A b67-year-old bclient bis bdischarged bfrom bthe bhospital bwith ba bprescription bfor
bdigoxin, b0.25 bmg bdaily. bWhich binstruction bshould bthe bnurse binclude bin bthis bclient's
bdischarge bteaching bplan? b- bcorrect banswers✔✔Take band brecord bradial bpulse brate
bdaily. b
Rationale: bMonitoring bpulse brate bis bvery bimportant bwhen btaking bdigoxin. bThe bclient
bshould bbe bfurther binstructed bto breport bpulse brates b<60 bor b>110 bbeats/min band bto
bwithhold bthe bdosage buntil bconsulting bwith bthe bhealth bcare bprovider bin bsuch ba
bcase. bVision bchange bis ban bindication bof bdrug btoxicity, band bthe bclient bshould bbe
binstructed bto breport bthis bimmediately.
A b55-year-old bclient bwas bdiagnosed bwith bschizophrenia b5 byears bearlier. bNumerous
bhospitalizations bhave boccurred bsince bthe bdiagnosis bbecause bof bnoncompliance
bwith bthe bprescribed bmedication bregimen. bWhich bdrug bmight bwork bbest bfor bthis
bparticular bclient? b- bcorrect banswers✔✔Fluphenazine bdecanoate b
Rationale: bFluphenazine, ban bantipsychotic bdrug bthat bcan bbe bgiven bIM, bhas ba brapid
bonset b(1 bto b2 bhours) band ba blong bduration bof baction b(up bto b3 bor b4 bweeks), bso bit
bwould bbe bthe bdrug bof bchoice bfor ba bnoncompliant bpsychotic bclient. bChlorpromazine
bHCl bis ban bantipsychotic bdrug bused bto btreat bschizophrenia band bis busually
badministered bPO b(IM bdoses bare bshort-acting). bThe bclient bmust bbe bcompliant bin
btaking bthis bdrug bfor bit bto bbe beffective. bLithium bcarbonate bis bmost beffective bwith
bmanic band bdepressive bbipolar baffective bdisorders. bDiazepam bis ban banti-anxiety
bdrug band bwould bnot bbe beffective bfor ba bpsychotic bdisorder.
, A bclient bis bbeing bdischarged bwith ba bprescription bfor bsulfasalazine bto btreat
bulcerative bcolitis. bWhich binstruction bshould bthe bnurse bprovide bto bthis bclient bprior
bto bdischarge? b- bcorrect banswers✔✔Drink bat bleast beight bglasses bof bfluid ba bday b
Rationale: bAdequate bhydration bis bimportant bfor ball bsulfa bdrugs bbecause bthey bcan
bcrystallize bin bthe burine. bIf bpossible, bthe bdrug bshould bbe btaken bafter beating bto
bprovide blonger bintestinal btransit btime. bMaintaining bgood boral bhygiene bis bimportant
bfor bother bmedications, bsuch bas bphenytoin, bbecause bof bthe bincidence bof bgingival
bhyperplasia, bDiscontinue buse bof bthe bdrug bgradually bis bimportant bfor bsteroid
badministration.
Amoxicillin, b500 bmg bPO bevery b8 bhours, bis bprescribed bfor ba bclient bwith ban
binfection. bThe bdrug bis bavailable bin ba bsuspension bof b125 bmg/5 bmL. bHow bmany
bmilliliters bshould bthe bnurse badminister bwith beach bdose? b- bcorrect banswers✔✔20
bmL b
Rationale: b500 bmg/x bmL b= b125 bmg/5 bmL b125x b= b2500 bx b= b20 bmL
A bclient bwith bacute blymphocytic bleukemia bisto bbegin bchemotherapy btoday. bThe
bhealth bcare bprovider's bprescription bspecifies bthat bondansetron bis bto bbe
badministered bIV b30 bminutes bprior bto bthe binfusion bof bcisplatin. bWhat bis bthe
brationale bfor badministering bZofran bprior bto bthe bchemotherapy binduction? b- bcorrect
banswers✔✔Reduction bor belimination bof bnausea band bvomiting b
Rationale: bOndansetron bis ba btype b3 breceptor b(5-HT3) bantagonist bthat bisrecognized
bfor bimproved bcontrol bof bacute bnausea band bvomiting bassociated bwith
bchemotherapy. b5-HT3 bantagonists bare bmost beffective bwhen badministered bIV bprior
bto bthe binduction bof bthe bchemotherapeutic bagent(s).
A bclient bwith bchronic bgouty barthritis bis btalking ballopurinol, b100 bmg bPO bdaily.
bWhich blaboratory bserum blevel bshould bthe bnurse breport bto bthe bhealth bcare
bprovider bto bdetermine bthe btherapeutic boutcome? b- bcorrect banswers✔✔Uric bacid
blevel b
Rationale: bThe bprimary btherapeutic boutcome bassociated bwith ballopurinol btherapy bis
breduced bserum buric bacid blevels bwith ba blower bfrequency bof bacute bgouty battacks,
bso buric bacid blevel bshould bbe breported bto bthe bhealth bcare bprovider
The bnurse bis breviewing bprescribed bmedications bwith ba bfemale bclient bwho bis
bpreparing bfor bdischarge. bThe bclient basks bthe bnurse bwhy bthe boral bdose bof ban
bopioid banalgesic bis bhigher bthan bthe bIV bdose bthat bshe breceived bduring
bhospitalization. bWhich bresponse bis bbest bfor bthe bnurse bto bprovide? b- bcorrect
banswers✔✔Oral bforms bof bdrugs bmust bpass bthrough bthe bliver bfirst, bwhere bmore bof
bthe bdose bis bmetabolized. b
Rationale: bOral bdoses bof bmedication bare busually blarger bthan bparenteral bdosesto
bcompensate bfor bthe bfirst-pass beffect bin bthe bliver bafter boral badministration, bwhich
bmetabolizes bmore bof bthe bdrug's bdose bbefore baffecting bits btherapeutic bresponse.
