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. Your patient complains of chest pain while sitting in the dental chair. Even though the
information is not recorded on his health history or pharmacologic history form, it is a
good idea for you to ask if he has taken sildenafil (Viagra) within the past 24 hours. The
use of nitroglycerine is contraindicated if sildenafil has been taken within 24 hours
because the nitroglycerine-sildenafil combination can precipitate a hypertensive crisis.
a. Both statements are TRUE.
b. Both statements are FALSE.
c. The first statement is TRUE; the second statement is FALSE.
d. The first statement is FALSE; the second statement is TRUE. - CORRECT ANSWER:
c. The first statement is TRUE; the second statement is FALSE.
The first statement is true, the second is false. Taking nitroglycerine within 24 hours of
sildenafil (Viagra) is contraindicated because the combination can cause dangerously
low blood pressure.
A drug effect that is NEITHER predictable NOR dose related is called a(n)
a. therapeutic effect.
b. toxic reaction.
c. side effect.
d. allergic reaction. - CORRECT ANSWER: d. allergic reaction.
Unlike other adverse reactions, allergic reactions are neither predictable nor dose-
related.
,Albuterol is a bronchodilator that can be administered via a metered-dose inhaler. It is
recommended for treating an acute asthma attack.
a. Both statements are TRUE.
b. Both statements are FALSE.
c. The first statement is TRUE; the second is FALSE.
d. The first statement is FALSE; the second is TRUE. - CORRECT ANSWER: a. Both
statements are TRUE
Albuterol is a bronchodilator administered via inhaler. It is recommended to treat acute
asthma attacks. Often it is given before a known trigger (i.e., stress or exercise) to
prevent an attack.
Alcohol consumption in combination with acetaminophen stimulates the breakdown of
acetaminophen, thereby increasing the toxic potential of acetaminophen use.
a. Both statements are TRUE.
b. Both statements are FALSE.
c. The first statement is TRUE; the second statement is FALSE.
d. The first statement is FALSE; the second statement is TRUE. - CORRECT ANSWER:
a. Both statements are TRUE.
Alcohol stimulates the oxidizing enzymes that metabolize acetaminophen to its toxic
metabolite. In this way it increases acetaminophen toxicity.
All of the following drugs inhibit platelet function EXCEPT
a. clopidogrel.
b. dipyridamole.
, c. ticlopidine.
d. aspirin. - CORRECT ANSWER: b. dipyridamole.
used to prolong the life of platelets in patients with prosthetic heart valves.
All the following are recommendations that you should make to patients with asthma
EXCEPT one. Which one is the exception?
a. Bring your inhaler (albuterol) to the dental appointment.
b. Rinse after using corticosteroid inhaler.
c. Avoid erythromycin.
d. Avoid aspirin.
e. Avoid acetaminophen - CORRECT ANSWER: e. Avoid acetaminophen
Acetaminophen and weak narcotic analgesics are probably OK for persons with
asthma.
All the following are true with regard to cytochromes P450 EXCEPT for which one?
a. Cytochromes P450 are located in the endoplasmic reticulum.
b. Cytochromes P450 exist as numerous isozymes.
c. Cytochromes P450 are involved in the first-pass effect.
d. Cytochromes P450 inactivate drugs through conjugation reactions. - CORRECT
ANSWER: d. Cytochromes P450 inactivate drugs through conjugation reactions.
Cytochromes P450 inactivate drugs but not through conjugation. They are involved in
phase I metabolism and metabolize drugs through oxidation and reduction reactions.