VMED 5255 - Hemolymphatic Viruses
1. Viruses that can result in lymphopenia?: 1. Coronaviruses
• Feline infectious peritonitis virus
• Canine CoV
• SARS-CoV-2
• MERS-CoV
2. Arteriviruses
• Porcine reproductive and respiratory syndrome virus
• Equine viral arteritis virus
3. Paramyxoviruses
• Canine distemper virus
• Newcastle disease virus
4. A
• Feline immunodeficiency virus
• Bovine leukemia virus
5. Pestiviruses
• Bovine viral diarrhea virus
• Classical swine fever virus
6. Herpesviruses
• Bovine herpesvirus 1
• Mareks disease virus
7. Adenoviruses
• Canine adenovirus 1
2. Consequences of viruses causing lymphopenia?: These viruses often result in immunosuppression, making
affected animals more susceptible to secondary bacterial infections
3. What could be other causes of lymphopenia?: High circulating glucocorticoids concentration, chylothorax,
lymphoma treatment, the use of UV irradiation, etc.
4. How can some viruses affect platelets?: •Platelet destruction
• Reduced production
• Increased consumption (due to immune-mediated mechanisms)
• DIC (Disseminated intravascular coagulation)
5. What virus affecting multiple species causes vascular damage leading to thrombocytopenia and DIC?:
Bluetongue Virus (BTV)
• Affects ruminants (sheep, cattle, goats, deer)
6. What pig viruses can result in thrombocytopenia?: African Swine Fever Virus (ASFV) in pigs
• Disseminated intravascular coagulation (DIC) and thrombocytopenia
Classical Swine Fever Virus (CSFV)
, VMED 5255 - Hemolymphatic Viruses
• Causes vascular damage and thrombocytopenia
Porcine Circovirus (PCV-2)
• Associated with immune suppression and thrombocytopenia
7. What bovine viruses can result in thrombocytopenia?: Bovine Viral Diarrhea Virus (BVDV) in cattle
• Immune-mediated destruction of platelets leads to thrombocytopenia
8. What equine viruses can result in thrombocytopenia?: Equine Infectious Anemia Virus (EIAV)
• A retrovirus that causes persistent infection, thrombocytopenia, and anemia
Equine Arteritis Virus (EAV)
• During acute infection causes vasculitis and thrombocytopenia
9. What canine viruses can result in thrombocytopenia?: Canine Parvovirus (CPV)
• Causes severe bone marrow suppression, leading to thrombocytopenia.
Canine Distemper Virus (CDV)
• Leads to thrombocytopenia due to bone marrow suppression and secondary infec- tions.
10.What tick-borne Rickettsial infection leads to viral-like immune suppres- sion and thrombocytopenia?:
Ehrlichia canis
11.What cat viruses can result in thrombocytopenia?: Feline Leukemia Virus (FeLV)
• Affects the bone marrow, leading to thrombocytopenia.
Feline Immunodeficiency Virus (FIV)
• Causes immune suppression and secondary effects, including thrombocytopenia
Feline Infectious Peritonitis (FIP, caused by feline coronavirus mutation)
• Can result in immune-mediated thrombocytopenia
12.What bird viruses can result in thrombocytopenia?: Infectious Bursal Dis- ease Virus (IBDV)
- Causes immunosuppression and thrombocytopenia in poultry
Avian Influenza Virus (HPAI strains)
- Can lead to thrombocytopenia due to endothelial damage and
1. Viruses that can result in lymphopenia?: 1. Coronaviruses
• Feline infectious peritonitis virus
• Canine CoV
• SARS-CoV-2
• MERS-CoV
2. Arteriviruses
• Porcine reproductive and respiratory syndrome virus
• Equine viral arteritis virus
3. Paramyxoviruses
• Canine distemper virus
• Newcastle disease virus
4. A
• Feline immunodeficiency virus
• Bovine leukemia virus
5. Pestiviruses
• Bovine viral diarrhea virus
• Classical swine fever virus
6. Herpesviruses
• Bovine herpesvirus 1
• Mareks disease virus
7. Adenoviruses
• Canine adenovirus 1
2. Consequences of viruses causing lymphopenia?: These viruses often result in immunosuppression, making
affected animals more susceptible to secondary bacterial infections
3. What could be other causes of lymphopenia?: High circulating glucocorticoids concentration, chylothorax,
lymphoma treatment, the use of UV irradiation, etc.
4. How can some viruses affect platelets?: •Platelet destruction
• Reduced production
• Increased consumption (due to immune-mediated mechanisms)
• DIC (Disseminated intravascular coagulation)
5. What virus affecting multiple species causes vascular damage leading to thrombocytopenia and DIC?:
Bluetongue Virus (BTV)
• Affects ruminants (sheep, cattle, goats, deer)
6. What pig viruses can result in thrombocytopenia?: African Swine Fever Virus (ASFV) in pigs
• Disseminated intravascular coagulation (DIC) and thrombocytopenia
Classical Swine Fever Virus (CSFV)
, VMED 5255 - Hemolymphatic Viruses
• Causes vascular damage and thrombocytopenia
Porcine Circovirus (PCV-2)
• Associated with immune suppression and thrombocytopenia
7. What bovine viruses can result in thrombocytopenia?: Bovine Viral Diarrhea Virus (BVDV) in cattle
• Immune-mediated destruction of platelets leads to thrombocytopenia
8. What equine viruses can result in thrombocytopenia?: Equine Infectious Anemia Virus (EIAV)
• A retrovirus that causes persistent infection, thrombocytopenia, and anemia
Equine Arteritis Virus (EAV)
• During acute infection causes vasculitis and thrombocytopenia
9. What canine viruses can result in thrombocytopenia?: Canine Parvovirus (CPV)
• Causes severe bone marrow suppression, leading to thrombocytopenia.
Canine Distemper Virus (CDV)
• Leads to thrombocytopenia due to bone marrow suppression and secondary infec- tions.
10.What tick-borne Rickettsial infection leads to viral-like immune suppres- sion and thrombocytopenia?:
Ehrlichia canis
11.What cat viruses can result in thrombocytopenia?: Feline Leukemia Virus (FeLV)
• Affects the bone marrow, leading to thrombocytopenia.
Feline Immunodeficiency Virus (FIV)
• Causes immune suppression and secondary effects, including thrombocytopenia
Feline Infectious Peritonitis (FIP, caused by feline coronavirus mutation)
• Can result in immune-mediated thrombocytopenia
12.What bird viruses can result in thrombocytopenia?: Infectious Bursal Dis- ease Virus (IBDV)
- Causes immunosuppression and thrombocytopenia in poultry
Avian Influenza Virus (HPAI strains)
- Can lead to thrombocytopenia due to endothelial damage and
