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fgfdgbnbvhfdgfd CS 416 - Dat Viz Week 1 EXCEL EXAM 1
68 terms 17 terms 144 terms
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FDA puts this warning as the strictest warning on the label. The
Black box warning medication is highly likely to cause the side effect it is warning
about.
Affinity of a drug is how strong the drug attaches to a receptor.
Agonist increases the effects of the drug
Partial Antagonist partially decreases the effect of the drug
Full Antagonist completely decreases the effect of the drug.
Neurotransmitter chemical messenger between neurons.
Cerebrum has two hemispheres. left to right
What does the right hemisphere The right hemisphere controls the left side of the body.
of the cerebrum control?
What does the left hemisphere The left hemisphere controls the right side of the body.
of the cerebrum control?
The hemispheres are divided frontal, parietal, occipital, temporal
into 4 lobes
Grey matter contains neuronal Hippocampus, the amygdala, andthe basal ganglia.
cell bodies. Pockets of grey
matter in the cerebrum include:
fear, anger, sadness, and AGGRESSION. It is the temporal lobe.
There is an amygdala on each side of the brain. Helps to store
The Amygdala processes what?
memories of bad events and presents that fear in the future.
Example: You were in a car accident. Now you are afraid to drive.
Hyperactive amygdala may be in schizophrenia and trauma
seen.
Hippocampus helps. make new memories
"Emotional brain" The hippocampus, amygdala, hypothalamus,
Limbic system
and thalamus. Antianxiety agents slow the limbic system.
shrinkage of the prefrontal cortex including the hippocampus
Chronic stress can cause.
and grey matter
, Shrinkage of the prefrontal to depression and addiction.
cortex may lead
Movement is regulated by the basal ganglia including movement of the diaphragm
Drugs that affect the basal may affect speech patterns (slurred speech, stuttering).
ganglia
• Basal ganglia - major role in motor responses and extrapyramidal side effects
Basal ganglia changes may EPS and tardive dyskinesia.
cause two types of movement
disturbances:
The brainstem is composed of Composed of the pons, medulla, and the midbrain
Composed of the pons, medulla, and the midbrain
• Basic vital life functions
• Brainstem regulates sleep and wake cycle, consciousness, and
wakefulness.
BRAIN FUNCTIONS -
• The Pons - regulates respirations and interprets senses such as
BRAINSTEM
smell, taste, hearing.
• Midbrain - eye movements, processing of visual and auditory
stimuli
*Medulla - digestion, sneezing, swallowing
• Motor control and cognitive processing
• Balance, coordination, posture, and gait
BRAIN FUNCTIONS -
• Impairments in attentional and emotional control in
CEREBELLUM
schizophrenia
• Lithium targets cerebellum function in bipolar disorder.
Filters sensory information before it reaches the cerebral cortex.
BRAIN FUNCTIONS -
• In Schizophrenia there is altered connections between the
THALAMUS
thalamus and the prefrontal cortex.
Maintains homeostasis
• Regulates temperature, blood pressure, libido, thirst, and
circadian rhythms.
• Releases neurohormones that direct secretions of hormones
BRAIN FUNCTIONS -
from the anterior pituitary gland.
HYPOTHALAMUS
• Hypothalamus -> corticotrophin-releasing hormone (CRH) ->
pituitary-> corticotrophin -> adrenal cortex-> cortisol
.• CRH release is disrupted in depression, Alzheimer's disease,
substance use disorder, and insomnia.
Cognition, motivation, and movement
• Stimulates the heart and blood flow to organs
Dopamine
• High levels: Schizophrenia, Mania.
Low levels: Parkinson’s disease, depression
Helps with skeletal muscle movement, arousal, memory,
sleep/wake cycle.
Acetylcholine High levels: depression
Low levels: Alzheimer’s disease, Huntington’s chorea, Parkinson’s
disease