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• NURS 5350 Final Guide – Pathophysiology Exam 3 (2025)

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• NURS 5350 Final Guide – Pathophysiology Exam 3 (2025)

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1. A nurse is assessing a client with a suspected myocardial
infarction (MI). Which finding would be most indicative of an MI?
A. Severe sharp chest pain that radiates to the left shoulder
B. Shortness of breath with a productive cough
C. Gradual onset of bilateral lower leg edema
D. Sudden dizziness with no associated chest pain
Answer: A) Severe sharp chest pain that radiates to the left
shoulder
Rationale: A common symptom of myocardial infarction is chest
pain that radiates to the left shoulder or arm. This is due to
ischemia affecting the heart muscle.

2. In which of the following conditions would you expect an
increase in erythrocyte sedimentation rate (ESR)?
A. Acute inflammation
B. Dehydration
C. Iron deficiency anemia
D. Chronic hypertension
Answer: A) Acute inflammation
Rationale: ESR is an indicator of inflammation. It increases during
acute inflammatory processes, such as infections, autoimmune
diseases, and other inflammatory conditions.

3. A patient with COPD has developed a barrel chest. What does
this physical finding indicate?
A. Emphysema
B. Pneumonia
C. Asthma
D. Acute bronchitis
Answer: A) Emphysema
Rationale: A barrel chest is a physical characteristic seen in

,emphysema, a type of COPD. It occurs due to the hyperinflation
of the lungs, which causes the chest to assume a rounded,
expanded shape.

4. What is the most common cause of secondary osteoporosis?
A. Calcium deficiency
B. Hyperparathyroidism
C. Long-term use of corticosteroids
D. Vitamin D deficiency
Answer: C) Long-term use of corticosteroids
Rationale: Long-term corticosteroid use is a major cause of
secondary osteoporosis due to its effect on bone metabolism,
leading to decreased bone density and increased fracture risk.

5. Which of the following would most likely cause a decrease in
blood pressure?
A. Activation of the sympathetic nervous system
B. Release of aldosterone
C. Release of antidiuretic hormone (ADH)
D. Decreased blood volume
Answer: D) Decreased blood volume
Rationale: Decreased blood volume reduces venous return, leading
to reduced cardiac output and a drop in blood pressure.

6. A patient with hypothyroidism is most likely to have which of
the following symptoms?
A. Weight loss
B. Increased heart rate
C. Cold intolerance
D. Heat intolerance
Answer: C) Cold intolerance
Rationale: Hypothyroidism leads to reduced metabolism, causing
symptoms such as cold intolerance, weight gain, and fatigue.

, 7. A patient with a history of gout presents with severe joint pain
in the big toe. What is the most likely cause of this pain?
A. Hyperuricemia
B. Osteoarthritis
C. Rheumatoid arthritis
D. Bone fracture
Answer: A) Hyperuricemia
Rationale: Gout is caused by the accumulation of uric acid crystals
in the joints, often beginning with the big toe. Elevated uric acid
levels (hyperuricemia) lead to these crystals forming and causing
intense pain.

8. What is a common complication of untreated hyperthyroidism?
A. Heart failure
B. Bradycardia
C. Hypoglycemia
D. Myxedema coma
Answer: A) Heart failure
Rationale: Untreated hyperthyroidism can lead to tachycardia and
increased cardiac workload, which can eventually result in heart
failure.

9. Which of the following is the primary treatment goal for a
patient with acute myocardial infarction (MI)?
A. Increase fluid intake
B. Reduce heart rate and oxygen demand
C. Prevent deep vein thrombosis
D. Enhance gastrointestinal function
Answer: B) Reduce heart rate and oxygen demand
Rationale: The primary goal in managing MI is to reduce the
heart's workload by decreasing heart rate and oxygen demand to
prevent further damage to the heart muscle.

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