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Pathophysiology Key Concepts – NURS501 2025

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Pathophysiology Key Concepts – NURS501 2025

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1. A patient with chronic kidney disease (CKD) is most at risk for
which of the following electrolyte imbalances?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypocalcemia
Answer: A) Hyperkalemia
Rationale: In CKD, the kidneys are unable to excrete potassium
effectively, leading to the accumulation of potassium in the blood,
resulting in hyperkalemia.

2. A patient with a history of chronic pancreatitis is at increased
risk for which of the following complications?
A. Diabetes mellitus
B. Hypoglycemia
C. Hyperkalemia
D. Asthma
Answer: A) Diabetes mellitus
Rationale: Chronic pancreatitis can damage the pancreas' ability
to secrete insulin, leading to insulin resistance and an increased
risk of diabetes mellitus.

3. Which of the following would you expect in a patient with
Addison’s disease?
A. Increased blood pressure
B. Hyperkalemia
C. Weight gain
D. Increased appetite
Answer: B) Hyperkalemia
Rationale: Addison’s disease, a disorder of the adrenal glands,
leads to decreased cortisol and aldosterone production. This

,results in fluid and sodium loss and potassium retention, causing
hyperkalemia.

4. A nurse is caring for a patient with pneumonia. Which of the
following is a common sign of pneumonia?
A. Cough with sputum production
B. Sudden weight gain
C. Seizures
D. Hemoptysis without cough
Answer: A) Cough with sputum production
Rationale: Pneumonia typically presents with symptoms such as a
productive cough with purulent sputum, fever, and difficulty
breathing due to inflammation in the lungs.

5. Which of the following is a common cause of hypoxemia?
A. Anemia
B. Asthma
C. Hypertension
D. Diabetes
Answer: B) Asthma
Rationale: Asthma causes bronchoconstriction and inflammation
in the airways, leading to decreased oxygen exchange and
resulting in hypoxemia.

6. What is the most common cause of peptic ulcers?
A. Stress
B. Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
C. Helicobacter pylori infection
D. Excessive alcohol consumption
Answer: C) Helicobacter pylori infection
Rationale: H. pylori infection is the leading cause of peptic ulcers
due to its ability to disrupt the mucosal lining of the stomach.

, 7. Which of the following is a classic sign of hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Tachycardia
D. Bradycardia
Answer: C) Tachycardia
Rationale: Hyperthyroidism is characterized by an overproduction
of thyroid hormones, leading to symptoms like tachycardia, heat
intolerance, and weight loss.

8. A patient presents with fever, jaundice, and dark urine. Which
condition might this indicate?
A. Hepatitis
B. Gallstones
C. Pancreatitis
D. Cirrhosis
Answer: A) Hepatitis
Rationale: Hepatitis can lead to liver inflammation, resulting in
jaundice (yellowing of the skin), dark urine, and fever.

9. A nurse is caring for a patient with hyperkalemia. What is the
most concerning sign of this condition?
A. Muscle weakness
B. Shortness of breath
C. Diarrhea
D. Nausea
Answer: A) Muscle weakness
Rationale: Hyperkalemia can cause muscle weakness and
potentially life-threatening arrhythmias due to its effect on the
electrical conductivity of the heart.

10. Which of the following factors is most likely to increase the
risk of deep vein thrombosis (DVT)?

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