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NURS501 Updated Slides – 2025 Pathophysiology

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NURS501 Updated Slides – 2025 Pathophysiology

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1. What is the main cause of liver cirrhosis?
A. Alcohol abuse
B. High-fat diet
C. Viral infections (e.g., hepatitis B or C)
D. Obesity
Answer: A) Alcohol abuse
Rationale: Chronic alcohol use is the leading cause of cirrhosis,
leading to liver fibrosis and eventual liver failure.

2. A nurse is caring for a patient with hyperkalemia. What is the
most concerning sign of this condition?
A. Muscle weakness
B. Shortness of breath
C. Diarrhea
D. Nausea
Answer: A) Muscle weakness
Rationale: Hyperkalemia can cause muscle weakness and
potentially life-threatening arrhythmias due to its effect on the
electrical conductivity of the heart.

3. Which of the following is a classic sign of hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Tachycardia
D. Bradycardia
Answer: C) Tachycardia
Rationale: Hyperthyroidism is characterized by an overproduction
of thyroid hormones, leading to symptoms like tachycardia, heat
intolerance, and weight loss.

4. What is the most common cause of peptic ulcers?

,A. Stress
B. Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
C. Helicobacter pylori infection
D. Excessive alcohol consumption
Answer: C) Helicobacter pylori infection
Rationale: H. pylori infection is the leading cause of peptic ulcers
due to its ability to disrupt the mucosal lining of the stomach.

5. What is the primary cause of atherosclerosis?
A. Decreased calcium intake
B. Chronic inflammation of the blood vessels
C. Increased HDL cholesterol
D. Vitamin D deficiency
Answer: B) Chronic inflammation of the blood vessels
Rationale: Atherosclerosis is primarily caused by the build-up of
plaque in the arteries, often triggered by chronic inflammation
and high levels of LDL cholesterol in the bloodstream.

6. A patient diagnosed with a brain tumor presents with sudden
weakness on one side of the body. What could this symptom
indicate?
A. Stroke
B. Seizure
C. Hemiparesis
D. Epilepsy
Answer: C) Hemiparesis
Rationale: Hemiparesis refers to weakness or partial paralysis on
one side of the body, which can occur with a brain tumor that
affects the motor areas of the brain.

7. A nurse is assessing a client with a suspected myocardial
infarction (MI). Which finding would be most indicative of an MI?
A. Severe sharp chest pain that radiates to the left shoulder

, B. Shortness of breath with a productive cough
C. Gradual onset of bilateral lower leg edema
D. Sudden dizziness with no associated chest pain
Answer: A) Severe sharp chest pain that radiates to the left
shoulder
Rationale: A common symptom of myocardial infarction is chest
pain that radiates to the left shoulder or arm. This is due to
ischemia affecting the heart muscle.

8. Which of the following is a primary complication of untreated
hypertension?
A. Diabetes
B. Stroke
C. Asthma
D. Hyperthyroidism
Answer: B) Stroke
Rationale: Untreated hypertension can cause damage to blood
vessels, increasing the risk of a stroke due to the development of
atherosclerosis or rupture of a weakened vessel.

9. A patient with a history of gout presents with severe joint pain
in the big toe. What is the most likely cause of this pain?
A. Hyperuricemia
B. Osteoarthritis
C. Rheumatoid arthritis
D. Bone fracture
Answer: A) Hyperuricemia
Rationale: Gout is caused by the accumulation of uric acid crystals
in the joints, often beginning with the big toe. Elevated uric acid
levels (hyperuricemia) lead to these crystals forming and causing
intense pain.

10. A patient presents with a chronic cough, wheezing, and

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