Test Bank Complete_
Lehne's Pharmacology For Nursing Care 12th Edition, (2024)
By Jacqueline Rosenjack Burchum & Laura D. Rosenthal
All Chapters 1-113| 19 Units| Latest Edition With Well Detailed Answers| Grade A+
From: [Bestmaxsolutions.stuvia
,UNIT I: INTRODUCTION --------------------------------------------------------------------------------------------- 7
Chapter 1: Orientation To Pharmacology ------------------------------------------------------------------------------7
Chapter 2: Application Of Pharmacology In Nursing Practice -------------------------------------------------- 13
Chapter 3: Drug Regulation, Development, Names, And Information --------------------------------------- 21
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY ----------------------------------------------------------- 26
Chapter 4: Pharmacokinetics -------------------------------------------------------------------------------------------- 26
Chapter 5: Pharmacodynamics ----------------------------------------------------------------------------------------- 34
Chapter 6: Drug Interactions -------------------------------------------------------------------------------------------- 39
Chapter 7: Adverse Drug Reactions And Medication Errors ---------------------------------------------------- 48
Chapter 8: Individual Variation In Drug Responses---------------------------------------------------------------- 57
Chapter 9: Genetic and Genomic Considerations ------------------------------------------------------------------ 64
Chapter 10. Introduction to Immunomodulators ------------------------------------------------------------------ 71
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ---------------------------------------------------------- 76
Chapter 11: Drug Therapy During Pregnancy And BreastFeeding --------------------------------------------- 76
Chapter 12: Drug Therapy In Pediatric Patients -------------------------------------------------------------------- 82
Chapter 13: Drug Therapy in Older Adults --------------------------------------------------------------------------- 89
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ---------------------------------------------------------- 97
SECTION 1: Introduction -------------------------------------------------------------------------------------------------- 97
Chapter 14: Basic Principles Of Neuropharmacology ---------------------------------------------------------------------- 97
Chapter 15: Physiology Of The Peripheral Nervous System --------------------------------------------------------------- 103
SECTION 2: Cholinergic Drugs ----------------------------------------------------------------------------------------- 109
Chapter 16: Muscarinic Agonists ------------------------------------------------------------------------------------------------ 109
Chapter 17: Muscarinic Antagonists -------------------------------------------------------------------------------------------- 115
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis ------------------------------------------ 125
Chapter 19: Drugs that Block Nicotinic Cholinergic Transmission ------------------------------------------------------- 132
SECTION 3: Adrenergic Drugs ----------------------------------------------------------------------------------------- 139
Chapter 20: Adrenergic Agonists ------------------------------------------------------------------------------------------------ 139
Chapter 21: Adrenergic Antagonists -------------------------------------------------------------------------------------------- 147
Chapter 22: Indirect-Acting Antiadrenergic Agents ------------------------------------------------------------------------- 157
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ------------------------------------------------------------- 164
SECTION 4: Introduction ------------------------------------------------------------------------------------------------ 164
Chapter 23: Introduction To Central Nervous System Pharmacology -------------------------------------------------- 164
SECTION 5: Drugs For Neurodegenerative Disorders ----------------------------------------------------------- 169
Chapter 24: Drugs For Parkinson’s Disease ----------------------------------------------------------------------------------- 169
Chapter 25: Drugs for Alzheimer Disease ------------------------------------------------------------------------------------- 178
Chapter 26: Drugs For Multiple Sclerosis -------------------------------------------------------------------------------------- 185
, SECTION 6: Neurologic Drugs ----------------------------------------------------------------------------------------- 193
Chapter 27: Drugs for Seizure Disorders--------------------------------------------------------------------------------------- 193
Chapter 28: Drugs For Muscle Spasm And Spasticity ----------------------------------------------------------------------- 205
SECTION 7: Drugs for Pain---------------------------------------------------------------------------------------------- 211
Chapter 29: Local Anesthetics --------------------------------------------------------------------------------------------------- 211
Chapter 30: General Anesthetics ------------------------------------------------------------------------------------------------ 218
Chapter 31: Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ---------------- 226
Chapter 32: Pain Management In Patients With Cancer ------------------------------------------------------------------- 235
Chapter 33: Drugs For Headache ------------------------------------------------------------------------------------------------ 246
SECTION 8: Psychotherapeutic Drugs ------------------------------------------------------------------------------- 253
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ----------------------------------------------------- 253
Chapter 35: Antidepressants ----------------------------------------------------------------------------------------------------- 263
Chapter 36: Drugs For Bipolar Disorder---------------------------------------------------------------------------------------- 274
Chapter 37: Sedative-Hypnotic Drugs ------------------------------------------------------------------------------------------ 281
Chapter 38: Management Of Anxiety Disorders ----------------------------------------------------------------------------- 292
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder ----------------- 297
SECTION 9: Substance Use Disorders ------------------------------------------------------------------------------- 305
Chapter 40: Substance Use Disorders I: Basic Considerations ------------------------------------------------------------ 305
Chapter 41: Substance Use Disorders II: Alcohol ---------------------------------------------------------------------------- 311
Chapter 42: Substance Use Disorders III: Nicotine -------------------------------------------------------------------------- 323
Chapter 43: Substance Use Disorders IV: Major Drugs of Abuse other Than Alcohol and Nicotine ------------- 329
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE --------------------------------- 341
Chapter 44: Diuretics ---------------------------------------------------------------------------------------------------- 341
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ------------------------------ 348
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ----------------------- 357
Chapter 46: Review Of Hemodynamics----------------------------------------------------------------------------- 357
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ------------------------------- 362
Chapter 48: Calcium Channel Blockers ----------------------------------------------------------------------------- 371
Chapter 49: Vasodilators ----------------------------------------------------------------------------------------------- 376
Chapter 50: Drugs For Hypertension -------------------------------------------------------------------------------- 383
Chapter 51: Drugs For Heart Failure --------------------------------------------------------------------------------- 395
Chapter 52: Antidysrhythmic Drugs --------------------------------------------------------------------------------- 408
Chapter 53: Drugs That Help Normalize Cholesterol and Triglyceride Levels----------------------------- 421
Chapter 54: Drugs For Angina Pectoris ----------------------------------------------------------------------------- 431
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ----------------------------------------- 442
Chapter 56: Management Of ST-Elevation Myocardial Infarction ------------------------------------------- 454
Chapter 57: Drugs For Hemophilia ----------------------------------------------------------------------------------- 461
, Chapter 58: Drugs For Deficiency Anemias ------------------------------------------------------------------------ 468
Chapter 59: Hematopoietic Agents ---------------------------------------------------------------------------------- 477
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ---------------------------------------------------------- 484
Chapter 60: Drugs For Diabetes Mellitus --------------------------------------------------------------------------- 484
Chapter 61: Drugs For Thyroid Disorders -------------------------------------------------------------------------- 494
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function --------------------------------------- 504
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ------------------------------------------------------- 511
UNIT IX: REPRODUCTIVE HEALTH ---------------------------------------------------------------------------- 519
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive Applications - 519
Chapter 65: Birth Control ---------------------------------------------------------------------------------------------- 526
Chapter 66: Drug Therapy Of Infertility ---------------------------------------------------------------------------- 536
Chapter 67: Drugs That Affect Uterine Function ----------------------------------------------------------------- 543
Chapter 68: Androgens ------------------------------------------------------------------------------------------------- 550
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia -------------------------- 559
Chapter 70: Transgender Health ------------------------------------------------------------------------------------- 566
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ------------------ 574
Chapter 71: Review Of The Immune System ---------------------------------------------------------------------- 574
Chapter 72: Childhood Immunization ------------------------------------------------------------------------------- 581
Chapter 73: Immunosuppressants ----------------------------------------------------------------------------------- 592
Chapter 74: Antihistamines-------------------------------------------------------------------------------------------- 600
Chapter 75: Cyclooxygenase Inhibitors: Nonsteroidal Anti-Inflammatory Drugs And Acetaminophen
-------------------------------------------------------------------------------------------------------------------------------- 610
Chapter 76: Glucocorticoids In Nonendocrine Disorders ------------------------------------------------------ 620
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS----------------------------------------------------- 629
Chapter 77: Drug Therapy Of Rheumatoid Arthritis------------------------------------------------------------- 629
Chapter 78: Drug Therapy Of Gout ---------------------------------------------------------------------------------- 635
Chapter 79: Drugs Affecting Calcium Levels And Bone Mineralization ------------------------------------- 641
UNIT XII: RESPIRATORY TRACT DRUGS --------------------------------------------------------------------- 651
Chapter 80: Drugs for Asthma and Chronic Obstructive Pulmonary Disease ----------------------------- 651
Chapter 81: Drugs For Allergic Rhinitis, Cough, And Colds ---------------------------------------------------- 662
UNIT XIII: GASTROINTESTINAL DRUGS---------------------------------------------------------------------- 671
, Chapter 82: Drugs For Peptic Ulcer Disease ----------------------------------------------------------------------- 671
Chapter 83: Laxatives --------------------------------------------------------------------------------------------------- 679
Chapter 84: Other Gastrointestinal Drugs ------------------------------------------------------------------------- 688
UNIT XIV: NUTRITION AND COMPLIMENTARY THERAPY ---------------------------------------------- 701
Chapter 85: Vitamins ---------------------------------------------------------------------------------------------------- 701
Chapter 86: Drugs For Weight Loss ---------------------------------------------------------------------------------- 711
Chapter 87. Complementary and Alternative Therapy --------------------------------------------------------- 721
UNIT XV: THERAPY OF INFECTIOUS DISEASES ------------------------------------------------------------ 730
Chapter 88: Basic Principles Of Antimicrobial Therapy --------------------------------------------------------- 730
Chapter 89: Drugs That Weaken The Bacterial Cell Wall I: Penicillins -------------------------------------- 739
Chapter 90: Drugs That Weaken the Bacterial Cell Wall II: Other Drugs ----------------------------------- 749
Chapter 91: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others 756
Chapter 92: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis ------------------------------ 769
Chapter 93: Sulfonamide Antibiotics and Trimethoprim ------------------------------------------------------ 780
Chapter 94: Drug Therapy Of Urinary Tract Infections --------------------------------------------------------- 788
Chapter 95: Antimycobacterial Agents: Drugs for Tuberculosis---------------------------------------------- 798
Chapter 96: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole, Daptomycin,
Rifampin, Rifaximin, and Fidaxomicin ------------------------------------------------------------------------------ 811
Chapter 97: Antifungal Agents ---------------------------------------------------------------------------------------- 817
Chapter 98: Antiviral Agents I: Drugs For Non-HIV Viral Infections ----------------------------------------- 830
Chapter 99: Antiviral Agents II: Drugs For HIV Infection And Related Opportunistic Infections ----- 839
Chapter 100: Drug Therapy Of Sexually Transmitted Diseases ----------------------------------------------- 848
Chapter 101: Antiseptics And Disinfectants ----------------------------------------------------------------------- 855
UNIT XVI: CHEMOTHERAPY OF PARASITIC DISEASES --------------------------------------------------- 862
Chapter 102: Anthelmintics ------------------------------------------------------------------------------------------- 862
Chapter 103: Antiprotozoal Drugs I: Antimalarial Agents ----------------------------------------------------- 868
Chapter 104: Antiprotozoal Drugs II: Miscellaneous Agents -------------------------------------------------- 875
Chapter 105: Ectoparasiticides --------------------------------------------------------------------------------------- 881
UNIT XVII: CANCER CHEMOTHERAPY ----------------------------------------------------------------------- 889
Chapter 106: Basic Principles Of Cancer Chemotherapy ------------------------------------------------------- 889
Chapter 107: Anticancer Drugs I: Cytotoxic Agents ------------------------------------------------------------- 899
, Chapter 108: Anticancer Drugs II: Hormonal Agents, Targeted Drugs, And Other Noncytotoxic
Anticancer Drugs --------------------------------------------------------------------------------------------------------- 909
UNIT XVIII: MISCELLANEOUS DRUGS AND THERAPIES ------------------------------------------------- 917
Chapter 109: Dr for the Eye Conditions and Diseases ---------------------------------------------------------- 917
Chapter 110: Drugs for Skin Conditions ---------------------------------------------------------------------------- 926
Chapter 111: Drugs for Ear Conditions------------------------------------------------------------------------------ 938
UNIT XIX: TOXICOLOGY ----------------------------------------------------------------------------------------- 946
Chapter 112: Management Of Poisoning -------------------------------------------------------------------------- 946
Chapter 113: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism -------------------- 953
,UNIT I: INTRODUCTION
Chapter 1: Orientation To Pharmacology
Jacqueline Rosenjack Burchum: Lehne's Pharmacology for Nursing Care 12th Edition, (2024) Test Bank
MULTIPLE CHOICE
1. A Nurse On A Medical-Surgical Unit Is Preparing To Administer A New
Antihypertensive Drug To A Patient. The Nurse Understands That One Of The Most
Important Properties Of An Ideal Drug Is Safety. Which Statement Best Reflects The
Concept Of Safety In Pharmacology?
A. A Drug That Cannot Cause Harmful Effects Regardless Of Dose
B. A Drug That Has Minimal Adverse Effects When Used Properly
C. A Drug That Is Not Metabolized By The Liver
D. A Drug That Is Effective For All Patients Equally
ANS: B.
No Drug Is Completely Free Of The Potential To Cause Harm. Safety Refers To The
Capacity Of A Drug To Cause Minimal Harmful Effects When Administered Correctly.
Nurses Assess Patients Before And After Administration To Mitigate Risks. Choice (A)
Is Incorrect Because No Drug Is Entirely Safe. (C) Relates To Pharmacokinetics, Not
Safety. (D) Is Incorrect Because Drug Response Varies Among Individuals.
DIF: Comprehension
REF: Properties Of An Ideal Drug – Safety
TOP: Nursing Process: Assessment
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
2. During Patient Rounds, A Nurse Notices That A Prescribed Medication For
Depression Also Causes Drowsiness. The Nurse Recalls That Selectivity Is One Of The
Ideal Drug Properties. What Does Drug Selectivity Imply?
A. The Drug Only Treats One Specific Condition
,B. The Drug Binds To Only One Receptor In The Body
C. The Drug Elicits Only The Response For Which It Is Given
D. The Drug Has No Adverse Effects
ANS: C.
Selectivity Means That A Drug Targets Specific Responses Or Actions Without
Affecting Other Systems. However, No Drug Is Completely Selective, Which Is Why
Side Effects Like Drowsiness May Occur. (A) Is Incorrect—Many Drugs Treat Multiple
Conditions. (B) Is A Partial Explanation Of Mechanism Of Action. (D) Is Unrealistic, As
All Drugs Carry The Potential For Side Effects.
DIF: Comprehension
REF: Properties Of An Ideal Drug – Selectivity
TOP: Nursing Process: Evaluation
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
3. A Nurse Is Teaching A Newly Diagnosed Diabetic Patient About Insulin Therapy. The
Patient Asks Why Their Provider Chose A Specific Insulin Formulation. The Nurse
Explains That The Time To Onset And Duration Of Action Depends On Which
Pharmacological Principle?
A. Pharmacodynamics
B. Pharmacogenomics
C. Pharmacokinetics
D. Therapeutic Index
ANS: C.
Pharmacokinetics Describes How The Body Affects A Drug, Including Absorption,
Distribution, Metabolism, And Excretion. The Onset And Duration Of Insulin Are
Influenced By These Processes. (A) Pharmacodynamics Is About What The Drug Does
To The Body. (B) Pharmacogenomics Involves Genetic Variation. (D) The Therapeutic
Index Refers To The Safety Margin.
DIF: Comprehension
,REF: Four Basic Pharmacologic Processes – Pharmacokinetics
TOP: Nursing Process: Implementation
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
4. While Evaluating A Patient’s Response To An IV Antibiotic For Sepsis, The Nurse
Notes A Sustained Fever And Increasing White Blood Cell Count. Based On Knowledge
Of Pharmacology, Which Property Of The Drug Is Now In Question?
A. Chemical Stability
B. Selectivity
C. Effectiveness
D. Ease Of Administration
ANS: C.
Effectiveness Is The Most Important Property Of A Drug—It Must Achieve The Desired
Therapeutic Outcome. If The Patient Continues To Show Signs Of Infection, The Drug
May Be Ineffective. (A) Chemical Stability Refers To Storage. (B) Selectivity Refers To
Producing Specific Responses. (D) Ease Of Administration Does Not Determine
Therapeutic Outcomes.
DIF: Analysis
REF: Properties Of An Ideal Drug – Effectiveness
TOP: Nursing Process: Evaluation
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
5. A Nurse Is Preparing To Discharge A Patient With A New Prescription For An Oral
Heart Failure Medication. The Nurse Notes The Medication Must Be Taken Three Times
Daily And May Cause Nausea. Which Factor Related To Drug Therapy Is The Nurse
Most Concerned About?
A. Therapeutic Index
B. Ease Of Administration
C. Bioavailability
D. Drug Interactions
, ANS: B.
Medications That Are Complex To Take Or Have Unpleasant Side Effects May Reduce
Patient Adherence. Drugs That Are Easy To Administer (E.G., Once-Daily Dosing,
Minimal Side Effects) Improve Compliance. (A) Therapeutic Index Involves Drug
Safety. (C) Bioavailability Refers To The Amount Of Drug Reaching Systemic
Circulation. (D) Drug Interactions Are Important, But Not The Primary Concern Here.
DIF: Application
REF: Additional Properties Of An Ideal Drug – Ease Of Administration
TOP: Nursing Process: Planning
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
MULTIPLE RESPONSE
1. Which Of The Following Are Considered Important Factors Contributing To The
Intensity Of A Drug Response? (Select All That Apply.)
A. Administration
B. Pharmacokinetics
C. Cost Of The Drug
D. Pharmacodynamics
E. Patient Adherence
Answers: A, B, D, E
Administration (A): Correct. This Includes Route, Dosage, And Timing—All Of Which
Affect How Much Of The Drug Reaches The Systemic Circulation And Its Overall
Effect.
Pharmacokinetics (B): Correct. This Involves The Movement Of Drugs Through The
Body (Absorption, Distribution, Metabolism, Excretion), All Of Which Influence The
Drug's Intensity And Duration.
Cost Of The Drug (C): Incorrect. While Cost Can Affect Patient Access And Adherence,
It Is Not A Pharmacological Factor Influencing Intensity Of Drug Response.
Lehne's Pharmacology For Nursing Care 12th Edition, (2024)
By Jacqueline Rosenjack Burchum & Laura D. Rosenthal
All Chapters 1-113| 19 Units| Latest Edition With Well Detailed Answers| Grade A+
From: [Bestmaxsolutions.stuvia
,UNIT I: INTRODUCTION --------------------------------------------------------------------------------------------- 7
Chapter 1: Orientation To Pharmacology ------------------------------------------------------------------------------7
Chapter 2: Application Of Pharmacology In Nursing Practice -------------------------------------------------- 13
Chapter 3: Drug Regulation, Development, Names, And Information --------------------------------------- 21
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY ----------------------------------------------------------- 26
Chapter 4: Pharmacokinetics -------------------------------------------------------------------------------------------- 26
Chapter 5: Pharmacodynamics ----------------------------------------------------------------------------------------- 34
Chapter 6: Drug Interactions -------------------------------------------------------------------------------------------- 39
Chapter 7: Adverse Drug Reactions And Medication Errors ---------------------------------------------------- 48
Chapter 8: Individual Variation In Drug Responses---------------------------------------------------------------- 57
Chapter 9: Genetic and Genomic Considerations ------------------------------------------------------------------ 64
Chapter 10. Introduction to Immunomodulators ------------------------------------------------------------------ 71
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ---------------------------------------------------------- 76
Chapter 11: Drug Therapy During Pregnancy And BreastFeeding --------------------------------------------- 76
Chapter 12: Drug Therapy In Pediatric Patients -------------------------------------------------------------------- 82
Chapter 13: Drug Therapy in Older Adults --------------------------------------------------------------------------- 89
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ---------------------------------------------------------- 97
SECTION 1: Introduction -------------------------------------------------------------------------------------------------- 97
Chapter 14: Basic Principles Of Neuropharmacology ---------------------------------------------------------------------- 97
Chapter 15: Physiology Of The Peripheral Nervous System --------------------------------------------------------------- 103
SECTION 2: Cholinergic Drugs ----------------------------------------------------------------------------------------- 109
Chapter 16: Muscarinic Agonists ------------------------------------------------------------------------------------------------ 109
Chapter 17: Muscarinic Antagonists -------------------------------------------------------------------------------------------- 115
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis ------------------------------------------ 125
Chapter 19: Drugs that Block Nicotinic Cholinergic Transmission ------------------------------------------------------- 132
SECTION 3: Adrenergic Drugs ----------------------------------------------------------------------------------------- 139
Chapter 20: Adrenergic Agonists ------------------------------------------------------------------------------------------------ 139
Chapter 21: Adrenergic Antagonists -------------------------------------------------------------------------------------------- 147
Chapter 22: Indirect-Acting Antiadrenergic Agents ------------------------------------------------------------------------- 157
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ------------------------------------------------------------- 164
SECTION 4: Introduction ------------------------------------------------------------------------------------------------ 164
Chapter 23: Introduction To Central Nervous System Pharmacology -------------------------------------------------- 164
SECTION 5: Drugs For Neurodegenerative Disorders ----------------------------------------------------------- 169
Chapter 24: Drugs For Parkinson’s Disease ----------------------------------------------------------------------------------- 169
Chapter 25: Drugs for Alzheimer Disease ------------------------------------------------------------------------------------- 178
Chapter 26: Drugs For Multiple Sclerosis -------------------------------------------------------------------------------------- 185
, SECTION 6: Neurologic Drugs ----------------------------------------------------------------------------------------- 193
Chapter 27: Drugs for Seizure Disorders--------------------------------------------------------------------------------------- 193
Chapter 28: Drugs For Muscle Spasm And Spasticity ----------------------------------------------------------------------- 205
SECTION 7: Drugs for Pain---------------------------------------------------------------------------------------------- 211
Chapter 29: Local Anesthetics --------------------------------------------------------------------------------------------------- 211
Chapter 30: General Anesthetics ------------------------------------------------------------------------------------------------ 218
Chapter 31: Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ---------------- 226
Chapter 32: Pain Management In Patients With Cancer ------------------------------------------------------------------- 235
Chapter 33: Drugs For Headache ------------------------------------------------------------------------------------------------ 246
SECTION 8: Psychotherapeutic Drugs ------------------------------------------------------------------------------- 253
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ----------------------------------------------------- 253
Chapter 35: Antidepressants ----------------------------------------------------------------------------------------------------- 263
Chapter 36: Drugs For Bipolar Disorder---------------------------------------------------------------------------------------- 274
Chapter 37: Sedative-Hypnotic Drugs ------------------------------------------------------------------------------------------ 281
Chapter 38: Management Of Anxiety Disorders ----------------------------------------------------------------------------- 292
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder ----------------- 297
SECTION 9: Substance Use Disorders ------------------------------------------------------------------------------- 305
Chapter 40: Substance Use Disorders I: Basic Considerations ------------------------------------------------------------ 305
Chapter 41: Substance Use Disorders II: Alcohol ---------------------------------------------------------------------------- 311
Chapter 42: Substance Use Disorders III: Nicotine -------------------------------------------------------------------------- 323
Chapter 43: Substance Use Disorders IV: Major Drugs of Abuse other Than Alcohol and Nicotine ------------- 329
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE --------------------------------- 341
Chapter 44: Diuretics ---------------------------------------------------------------------------------------------------- 341
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ------------------------------ 348
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ----------------------- 357
Chapter 46: Review Of Hemodynamics----------------------------------------------------------------------------- 357
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ------------------------------- 362
Chapter 48: Calcium Channel Blockers ----------------------------------------------------------------------------- 371
Chapter 49: Vasodilators ----------------------------------------------------------------------------------------------- 376
Chapter 50: Drugs For Hypertension -------------------------------------------------------------------------------- 383
Chapter 51: Drugs For Heart Failure --------------------------------------------------------------------------------- 395
Chapter 52: Antidysrhythmic Drugs --------------------------------------------------------------------------------- 408
Chapter 53: Drugs That Help Normalize Cholesterol and Triglyceride Levels----------------------------- 421
Chapter 54: Drugs For Angina Pectoris ----------------------------------------------------------------------------- 431
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ----------------------------------------- 442
Chapter 56: Management Of ST-Elevation Myocardial Infarction ------------------------------------------- 454
Chapter 57: Drugs For Hemophilia ----------------------------------------------------------------------------------- 461
, Chapter 58: Drugs For Deficiency Anemias ------------------------------------------------------------------------ 468
Chapter 59: Hematopoietic Agents ---------------------------------------------------------------------------------- 477
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ---------------------------------------------------------- 484
Chapter 60: Drugs For Diabetes Mellitus --------------------------------------------------------------------------- 484
Chapter 61: Drugs For Thyroid Disorders -------------------------------------------------------------------------- 494
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function --------------------------------------- 504
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ------------------------------------------------------- 511
UNIT IX: REPRODUCTIVE HEALTH ---------------------------------------------------------------------------- 519
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive Applications - 519
Chapter 65: Birth Control ---------------------------------------------------------------------------------------------- 526
Chapter 66: Drug Therapy Of Infertility ---------------------------------------------------------------------------- 536
Chapter 67: Drugs That Affect Uterine Function ----------------------------------------------------------------- 543
Chapter 68: Androgens ------------------------------------------------------------------------------------------------- 550
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia -------------------------- 559
Chapter 70: Transgender Health ------------------------------------------------------------------------------------- 566
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ------------------ 574
Chapter 71: Review Of The Immune System ---------------------------------------------------------------------- 574
Chapter 72: Childhood Immunization ------------------------------------------------------------------------------- 581
Chapter 73: Immunosuppressants ----------------------------------------------------------------------------------- 592
Chapter 74: Antihistamines-------------------------------------------------------------------------------------------- 600
Chapter 75: Cyclooxygenase Inhibitors: Nonsteroidal Anti-Inflammatory Drugs And Acetaminophen
-------------------------------------------------------------------------------------------------------------------------------- 610
Chapter 76: Glucocorticoids In Nonendocrine Disorders ------------------------------------------------------ 620
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS----------------------------------------------------- 629
Chapter 77: Drug Therapy Of Rheumatoid Arthritis------------------------------------------------------------- 629
Chapter 78: Drug Therapy Of Gout ---------------------------------------------------------------------------------- 635
Chapter 79: Drugs Affecting Calcium Levels And Bone Mineralization ------------------------------------- 641
UNIT XII: RESPIRATORY TRACT DRUGS --------------------------------------------------------------------- 651
Chapter 80: Drugs for Asthma and Chronic Obstructive Pulmonary Disease ----------------------------- 651
Chapter 81: Drugs For Allergic Rhinitis, Cough, And Colds ---------------------------------------------------- 662
UNIT XIII: GASTROINTESTINAL DRUGS---------------------------------------------------------------------- 671
, Chapter 82: Drugs For Peptic Ulcer Disease ----------------------------------------------------------------------- 671
Chapter 83: Laxatives --------------------------------------------------------------------------------------------------- 679
Chapter 84: Other Gastrointestinal Drugs ------------------------------------------------------------------------- 688
UNIT XIV: NUTRITION AND COMPLIMENTARY THERAPY ---------------------------------------------- 701
Chapter 85: Vitamins ---------------------------------------------------------------------------------------------------- 701
Chapter 86: Drugs For Weight Loss ---------------------------------------------------------------------------------- 711
Chapter 87. Complementary and Alternative Therapy --------------------------------------------------------- 721
UNIT XV: THERAPY OF INFECTIOUS DISEASES ------------------------------------------------------------ 730
Chapter 88: Basic Principles Of Antimicrobial Therapy --------------------------------------------------------- 730
Chapter 89: Drugs That Weaken The Bacterial Cell Wall I: Penicillins -------------------------------------- 739
Chapter 90: Drugs That Weaken the Bacterial Cell Wall II: Other Drugs ----------------------------------- 749
Chapter 91: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others 756
Chapter 92: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis ------------------------------ 769
Chapter 93: Sulfonamide Antibiotics and Trimethoprim ------------------------------------------------------ 780
Chapter 94: Drug Therapy Of Urinary Tract Infections --------------------------------------------------------- 788
Chapter 95: Antimycobacterial Agents: Drugs for Tuberculosis---------------------------------------------- 798
Chapter 96: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole, Daptomycin,
Rifampin, Rifaximin, and Fidaxomicin ------------------------------------------------------------------------------ 811
Chapter 97: Antifungal Agents ---------------------------------------------------------------------------------------- 817
Chapter 98: Antiviral Agents I: Drugs For Non-HIV Viral Infections ----------------------------------------- 830
Chapter 99: Antiviral Agents II: Drugs For HIV Infection And Related Opportunistic Infections ----- 839
Chapter 100: Drug Therapy Of Sexually Transmitted Diseases ----------------------------------------------- 848
Chapter 101: Antiseptics And Disinfectants ----------------------------------------------------------------------- 855
UNIT XVI: CHEMOTHERAPY OF PARASITIC DISEASES --------------------------------------------------- 862
Chapter 102: Anthelmintics ------------------------------------------------------------------------------------------- 862
Chapter 103: Antiprotozoal Drugs I: Antimalarial Agents ----------------------------------------------------- 868
Chapter 104: Antiprotozoal Drugs II: Miscellaneous Agents -------------------------------------------------- 875
Chapter 105: Ectoparasiticides --------------------------------------------------------------------------------------- 881
UNIT XVII: CANCER CHEMOTHERAPY ----------------------------------------------------------------------- 889
Chapter 106: Basic Principles Of Cancer Chemotherapy ------------------------------------------------------- 889
Chapter 107: Anticancer Drugs I: Cytotoxic Agents ------------------------------------------------------------- 899
, Chapter 108: Anticancer Drugs II: Hormonal Agents, Targeted Drugs, And Other Noncytotoxic
Anticancer Drugs --------------------------------------------------------------------------------------------------------- 909
UNIT XVIII: MISCELLANEOUS DRUGS AND THERAPIES ------------------------------------------------- 917
Chapter 109: Dr for the Eye Conditions and Diseases ---------------------------------------------------------- 917
Chapter 110: Drugs for Skin Conditions ---------------------------------------------------------------------------- 926
Chapter 111: Drugs for Ear Conditions------------------------------------------------------------------------------ 938
UNIT XIX: TOXICOLOGY ----------------------------------------------------------------------------------------- 946
Chapter 112: Management Of Poisoning -------------------------------------------------------------------------- 946
Chapter 113: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism -------------------- 953
,UNIT I: INTRODUCTION
Chapter 1: Orientation To Pharmacology
Jacqueline Rosenjack Burchum: Lehne's Pharmacology for Nursing Care 12th Edition, (2024) Test Bank
MULTIPLE CHOICE
1. A Nurse On A Medical-Surgical Unit Is Preparing To Administer A New
Antihypertensive Drug To A Patient. The Nurse Understands That One Of The Most
Important Properties Of An Ideal Drug Is Safety. Which Statement Best Reflects The
Concept Of Safety In Pharmacology?
A. A Drug That Cannot Cause Harmful Effects Regardless Of Dose
B. A Drug That Has Minimal Adverse Effects When Used Properly
C. A Drug That Is Not Metabolized By The Liver
D. A Drug That Is Effective For All Patients Equally
ANS: B.
No Drug Is Completely Free Of The Potential To Cause Harm. Safety Refers To The
Capacity Of A Drug To Cause Minimal Harmful Effects When Administered Correctly.
Nurses Assess Patients Before And After Administration To Mitigate Risks. Choice (A)
Is Incorrect Because No Drug Is Entirely Safe. (C) Relates To Pharmacokinetics, Not
Safety. (D) Is Incorrect Because Drug Response Varies Among Individuals.
DIF: Comprehension
REF: Properties Of An Ideal Drug – Safety
TOP: Nursing Process: Assessment
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
2. During Patient Rounds, A Nurse Notices That A Prescribed Medication For
Depression Also Causes Drowsiness. The Nurse Recalls That Selectivity Is One Of The
Ideal Drug Properties. What Does Drug Selectivity Imply?
A. The Drug Only Treats One Specific Condition
,B. The Drug Binds To Only One Receptor In The Body
C. The Drug Elicits Only The Response For Which It Is Given
D. The Drug Has No Adverse Effects
ANS: C.
Selectivity Means That A Drug Targets Specific Responses Or Actions Without
Affecting Other Systems. However, No Drug Is Completely Selective, Which Is Why
Side Effects Like Drowsiness May Occur. (A) Is Incorrect—Many Drugs Treat Multiple
Conditions. (B) Is A Partial Explanation Of Mechanism Of Action. (D) Is Unrealistic, As
All Drugs Carry The Potential For Side Effects.
DIF: Comprehension
REF: Properties Of An Ideal Drug – Selectivity
TOP: Nursing Process: Evaluation
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
3. A Nurse Is Teaching A Newly Diagnosed Diabetic Patient About Insulin Therapy. The
Patient Asks Why Their Provider Chose A Specific Insulin Formulation. The Nurse
Explains That The Time To Onset And Duration Of Action Depends On Which
Pharmacological Principle?
A. Pharmacodynamics
B. Pharmacogenomics
C. Pharmacokinetics
D. Therapeutic Index
ANS: C.
Pharmacokinetics Describes How The Body Affects A Drug, Including Absorption,
Distribution, Metabolism, And Excretion. The Onset And Duration Of Insulin Are
Influenced By These Processes. (A) Pharmacodynamics Is About What The Drug Does
To The Body. (B) Pharmacogenomics Involves Genetic Variation. (D) The Therapeutic
Index Refers To The Safety Margin.
DIF: Comprehension
,REF: Four Basic Pharmacologic Processes – Pharmacokinetics
TOP: Nursing Process: Implementation
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
4. While Evaluating A Patient’s Response To An IV Antibiotic For Sepsis, The Nurse
Notes A Sustained Fever And Increasing White Blood Cell Count. Based On Knowledge
Of Pharmacology, Which Property Of The Drug Is Now In Question?
A. Chemical Stability
B. Selectivity
C. Effectiveness
D. Ease Of Administration
ANS: C.
Effectiveness Is The Most Important Property Of A Drug—It Must Achieve The Desired
Therapeutic Outcome. If The Patient Continues To Show Signs Of Infection, The Drug
May Be Ineffective. (A) Chemical Stability Refers To Storage. (B) Selectivity Refers To
Producing Specific Responses. (D) Ease Of Administration Does Not Determine
Therapeutic Outcomes.
DIF: Analysis
REF: Properties Of An Ideal Drug – Effectiveness
TOP: Nursing Process: Evaluation
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
5. A Nurse Is Preparing To Discharge A Patient With A New Prescription For An Oral
Heart Failure Medication. The Nurse Notes The Medication Must Be Taken Three Times
Daily And May Cause Nausea. Which Factor Related To Drug Therapy Is The Nurse
Most Concerned About?
A. Therapeutic Index
B. Ease Of Administration
C. Bioavailability
D. Drug Interactions
, ANS: B.
Medications That Are Complex To Take Or Have Unpleasant Side Effects May Reduce
Patient Adherence. Drugs That Are Easy To Administer (E.G., Once-Daily Dosing,
Minimal Side Effects) Improve Compliance. (A) Therapeutic Index Involves Drug
Safety. (C) Bioavailability Refers To The Amount Of Drug Reaching Systemic
Circulation. (D) Drug Interactions Are Important, But Not The Primary Concern Here.
DIF: Application
REF: Additional Properties Of An Ideal Drug – Ease Of Administration
TOP: Nursing Process: Planning
MSC: NCLEX: Physiologic Integrity – Pharmacologic And Parenteral Therapies
MULTIPLE RESPONSE
1. Which Of The Following Are Considered Important Factors Contributing To The
Intensity Of A Drug Response? (Select All That Apply.)
A. Administration
B. Pharmacokinetics
C. Cost Of The Drug
D. Pharmacodynamics
E. Patient Adherence
Answers: A, B, D, E
Administration (A): Correct. This Includes Route, Dosage, And Timing—All Of Which
Affect How Much Of The Drug Reaches The Systemic Circulation And Its Overall
Effect.
Pharmacokinetics (B): Correct. This Involves The Movement Of Drugs Through The
Body (Absorption, Distribution, Metabolism, Excretion), All Of Which Influence The
Drug's Intensity And Duration.
Cost Of The Drug (C): Incorrect. While Cost Can Affect Patient Access And Adherence,
It Is Not A Pharmacological Factor Influencing Intensity Of Drug Response.
