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NURS 501 Pathophysiology Highlights – 2025 Syllabus

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NURS 501 Pathophysiology Highlights – 2025 Syllabus

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1. A patient with acute bacterial meningitis is likely to experience
which of the following?
A. Increased thirst and urination
B. Severe headache and neck stiffness
C. Joint pain and swelling
D. Abdominal pain and bloating
Answer: B) Severe headache and neck stiffness
Rationale: Acute bacterial meningitis causes inflammation of the
meninges, leading to symptoms like severe headache, neck
stiffness, photophobia, and fever.

2. Which of the following would you expect in a patient with
Addison’s disease?
A. Increased blood pressure
B. Hyperkalemia
C. Weight gain
D. Increased appetite
Answer: B) Hyperkalemia
Rationale: Addison’s disease, a disorder of the adrenal glands,
leads to decreased cortisol and aldosterone production. This
results in fluid and sodium loss and potassium retention, causing
hyperkalemia.

3. Which of the following is a classic sign of hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Tachycardia
D. Bradycardia
Answer: C) Tachycardia
Rationale: Hyperthyroidism is characterized by an overproduction
of thyroid hormones, leading to symptoms like tachycardia, heat

,intolerance, and weight loss.

4. Which of the following factors is most likely to increase the
risk of deep vein thrombosis (DVT)?
A. Frequent physical activity
B. Use of oral contraceptives
C. Low body weight
D. Dehydration
Answer: B) Use of oral contraceptives
Rationale: Oral contraceptives can increase clotting factor
production, which elevates the risk of DVT.

5. What is a key characteristic of Crohn's disease?
A. Continuous inflammation of the colon
B. Painless, non-bloody diarrhea
C. Skip lesions along the gastrointestinal tract
D. Gallstone formation
Answer: C) Skip lesions along the gastrointestinal tract
Rationale: Crohn’s disease is characterized by inflammation that
can occur in patches (skip lesions) throughout the gastrointestinal
tract, leading to symptoms like diarrhea, abdominal pain, and
weight loss.

6. What is the most common cause of peptic ulcers?
A. Stress
B. Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
C. Helicobacter pylori infection
D. Excessive alcohol consumption
Answer: C) Helicobacter pylori infection
Rationale: H. pylori infection is the leading cause of peptic ulcers
due to its ability to disrupt the mucosal lining of the stomach.

7. A patient with COPD has developed a barrel chest. What does

, this physical finding indicate?
A. Emphysema
B. Pneumonia
C. Asthma
D. Acute bronchitis
Answer: A) Emphysema
Rationale: A barrel chest is a physical characteristic seen in
emphysema, a type of COPD. It occurs due to the hyperinflation
of the lungs, which causes the chest to assume a rounded,
expanded shape.

8. A nurse is caring for a patient with hyperkalemia. What is the
most concerning sign of this condition?
A. Muscle weakness
B. Shortness of breath
C. Diarrhea
D. Nausea
Answer: A) Muscle weakness
Rationale: Hyperkalemia can cause muscle weakness and
potentially life-threatening arrhythmias due to its effect on the
electrical conductivity of the heart.

9. What is a common complication of untreated hyperthyroidism?
A. Heart failure
B. Bradycardia
C. Hypoglycemia
D. Myxedema coma
Answer: A) Heart failure
Rationale: Untreated hyperthyroidism can lead to tachycardia and
increased cardiac workload, which can eventually result in heart
failure.

10. A patient with cirrhosis has developed ascites. Which of the

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