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• NURS 5350: Advanced Pathophysiology – 2025 Exam 3 Study Guide

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• NURS 5350: Advanced Pathophysiology – 2025 Exam 3 Study Guide

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1. A patient with a diagnosis of systemic lupus erythematosus
(SLE) is at increased risk for which of the following?
A. Infection
B. Weight loss
C. Hyperthyroidism
D. Stroke
Answer: A) Infection
Rationale: SLE is an autoimmune disorder that affects the immune
system, leaving the patient at higher risk for infections due to
immunosuppressive therapy and the disease itself.

2. Which of the following is a typical sign of hypoglycemia?
A. Increased thirst
B. Shaking and sweating
C. Increased urination
D. Elevated blood pressure
Answer: B) Shaking and sweating
Rationale: Hypoglycemia causes symptoms such as shaking,
sweating, and confusion due to the body's response to low blood
sugar levels.

3. In which condition would you expect to find a low white blood
cell (WBC) count?
A. Viral infection
B. Leukemia
C. Bacterial infection
D. Bone marrow suppression
Answer: D) Bone marrow suppression
Rationale: Bone marrow suppression, often caused by
chemotherapy or certain diseases, can result in low WBC counts
(leukopenia).

,4. What is a classic symptom of Parkinson’s disease?
A. Muscle rigidity
B. Hypotension
C. Polyuria
D. Weight gain
Answer: A) Muscle rigidity
Rationale: Parkinson’s disease is characterized by symptoms such
as muscle rigidity, tremors, and bradykinesia due to a loss of
dopaminergic neurons in the brain.

5. What is the main cause of liver cirrhosis?
A. Alcohol abuse
B. High-fat diet
C. Viral infections (e.g., hepatitis B or C)
D. Obesity
Answer: A) Alcohol abuse
Rationale: Chronic alcohol use is the leading cause of cirrhosis,
leading to liver fibrosis and eventual liver failure.

6. A patient with hypothyroidism is most likely to have which of
the following symptoms?
A. Weight loss
B. Increased heart rate
C. Cold intolerance
D. Heat intolerance
Answer: C) Cold intolerance
Rationale: Hypothyroidism leads to reduced metabolism, causing
symptoms such as cold intolerance, weight gain, and fatigue.

7. Which of the following is the primary treatment goal for a
patient with acute myocardial infarction (MI)?
A. Increase fluid intake

, B. Reduce heart rate and oxygen demand
C. Prevent deep vein thrombosis
D. Enhance gastrointestinal function
Answer: B) Reduce heart rate and oxygen demand
Rationale: The primary goal in managing MI is to reduce the
heart's workload by decreasing heart rate and oxygen demand to
prevent further damage to the heart muscle.

8. Which of the following is the most common cause of stroke?
A. Aneurysm rupture
B. Ischemia due to a clot
C. Brain tumor
D. Hypertension
Answer: B) Ischemia due to a clot
Rationale: Ischemic strokes are the most common type of stroke
and occur when a clot blocks blood flow to the brain.

9. A patient with COPD has developed a barrel chest. What does
this physical finding indicate?
A. Emphysema
B. Pneumonia
C. Asthma
D. Acute bronchitis
Answer: A) Emphysema
Rationale: A barrel chest is a physical characteristic seen in
emphysema, a type of COPD. It occurs due to the hyperinflation
of the lungs, which causes the chest to assume a rounded,
expanded shape.

10. A patient has been diagnosed with tuberculosis (TB). Which of
the following is the most common symptom?
A. Night sweats
B. Joint pain

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