WGU D027 /Advanced WGU D027 Actual
Exam/ All Questions with Correct Answers/
Updated 2025-2026.
,What organ does cystic fibrosis affect? - ANSWER - Affects the pancreas causing secretions into the lungs
What is Klinefelter syndrome? - ANSWER - An extra X chromosome for males so example XXY causing
female-like qualities
What is Turner Syndrome? - ANSWER - females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - ANSWER - a condition in which the synthesis of the beta-globin chains is decreased or
absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER - Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly toxic to lymphoid
tissues Selective estrogen receptor modulators (SERM) - for hormone receptor positive and advanced breast cancer.
(Tomaxafin - reduces risk and recurrence risk) - ANSWER - Glucocorticoids
What is the normal ejection fraction? - ANSWER - 55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWER - Preserved
What are symptoms of left sided heart failure? - ANSWER - Think PULMONARY. JVD, FVO, rails, S3
murmurs. Number one cause of right sided heart failure!
pg. 1
,What are symptoms of right sided heart failure? - ANSWER - Think peripheral vascular. Lower extremity edema,
abdominal distension.
What is the gold standard lab test for heart failure? - ANSWER - BNP. Heart failure is a result greater than 100
What heart disease is worse with exertion? - ANSWER - Ischemic heart disease because the demand requirements are
higher.
What should you assess before giving Digoxin? - ANSWER - Apical pulse
How should Warfarin be started? - ANSWER - Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to hyperinflation
- ANSWER - Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - ANSWER - Bronchitis
What is a chronic inflammatory obstruction of bronchi? - ANSWER - Asthma, Triggers cause mucus to clog
bronchial tubes.
What causes an overbite and buffalo hump? - ANSWER - Endocrine disorder called acromegaly (overproduction of
growth hormone)
What causes Addison's disease? - ANSWER - Decreased glucocorticoid (due to autoimmune destruction of
adrenal cortex)
What causes Cushing's syndrome? - ANSWER - excess cortisol
What causes Grave's disease? - ANSWER - overproduction of thyroid hormone. HYPERthyroidism.
pg. 2
, When should you instruct the patient to take their FIRST dose of antihypertensive? - ANSWER - At night to avoid
orthostatic hypotension. Educate slow position changes and lay down if needed.
What are side effects of ACE inhibitors? - ANSWER - dry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - ANSWER - Nonselective beta
blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - ANSWER - Verapamil
What side effect should you watch for in a patient taking a statin drug? - ANSWER - Muscle pain which can lead
to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? - ANSWER - Thiazide diuretics
What type of drug is spironolactone? - ANSWER - potassium sparing diuretic
Which type of insulin is the most painful during injection? - ANSWER - Lantus (long-acting)
Why test glycosylated hemoglobin (HgbA1c)? - ANSWER - Most reliable assessment of blood sugar over the past
3 months. The goal is < 6.5%. A poor result is > 9%
What is the normal range for TSH level? - ANSWER - The normal range of TSH levels is 0.4 to 4.0 milli-
international units per liter. If you're already being treated for a thyroid disorder, the normal range is 0.5 to 3.0
milli-international units per liter. A value ABOVE the normal range usually indicates
hypothyroidism.
pg. 3
Exam/ All Questions with Correct Answers/
Updated 2025-2026.
,What organ does cystic fibrosis affect? - ANSWER - Affects the pancreas causing secretions into the lungs
What is Klinefelter syndrome? - ANSWER - An extra X chromosome for males so example XXY causing
female-like qualities
What is Turner Syndrome? - ANSWER - females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - ANSWER - a condition in which the synthesis of the beta-globin chains is decreased or
absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER - Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly toxic to lymphoid
tissues Selective estrogen receptor modulators (SERM) - for hormone receptor positive and advanced breast cancer.
(Tomaxafin - reduces risk and recurrence risk) - ANSWER - Glucocorticoids
What is the normal ejection fraction? - ANSWER - 55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWER - Preserved
What are symptoms of left sided heart failure? - ANSWER - Think PULMONARY. JVD, FVO, rails, S3
murmurs. Number one cause of right sided heart failure!
pg. 1
,What are symptoms of right sided heart failure? - ANSWER - Think peripheral vascular. Lower extremity edema,
abdominal distension.
What is the gold standard lab test for heart failure? - ANSWER - BNP. Heart failure is a result greater than 100
What heart disease is worse with exertion? - ANSWER - Ischemic heart disease because the demand requirements are
higher.
What should you assess before giving Digoxin? - ANSWER - Apical pulse
How should Warfarin be started? - ANSWER - Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to hyperinflation
- ANSWER - Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - ANSWER - Bronchitis
What is a chronic inflammatory obstruction of bronchi? - ANSWER - Asthma, Triggers cause mucus to clog
bronchial tubes.
What causes an overbite and buffalo hump? - ANSWER - Endocrine disorder called acromegaly (overproduction of
growth hormone)
What causes Addison's disease? - ANSWER - Decreased glucocorticoid (due to autoimmune destruction of
adrenal cortex)
What causes Cushing's syndrome? - ANSWER - excess cortisol
What causes Grave's disease? - ANSWER - overproduction of thyroid hormone. HYPERthyroidism.
pg. 2
, When should you instruct the patient to take their FIRST dose of antihypertensive? - ANSWER - At night to avoid
orthostatic hypotension. Educate slow position changes and lay down if needed.
What are side effects of ACE inhibitors? - ANSWER - dry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - ANSWER - Nonselective beta
blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - ANSWER - Verapamil
What side effect should you watch for in a patient taking a statin drug? - ANSWER - Muscle pain which can lead
to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? - ANSWER - Thiazide diuretics
What type of drug is spironolactone? - ANSWER - potassium sparing diuretic
Which type of insulin is the most painful during injection? - ANSWER - Lantus (long-acting)
Why test glycosylated hemoglobin (HgbA1c)? - ANSWER - Most reliable assessment of blood sugar over the past
3 months. The goal is < 6.5%. A poor result is > 9%
What is the normal range for TSH level? - ANSWER - The normal range of TSH levels is 0.4 to 4.0 milli-
international units per liter. If you're already being treated for a thyroid disorder, the normal range is 0.5 to 3.0
milli-international units per liter. A value ABOVE the normal range usually indicates
hypothyroidism.
pg. 3
