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• 2025 NURS 6230 Midterm Exam Advanced Pathophysiology Questions

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• 2025 NURS 6230 Midterm Exam Advanced Pathophysiology Questions

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1. A patient has been diagnosed with tuberculosis (TB). Which of
the following is the most common symptom?
A. Night sweats
B. Joint pain
C. Hematuria
D. Abdominal pain
Answer: A) Night sweats
Rationale: Night sweats are a classic symptom of tuberculosis,
along with cough and weight loss.

2. Which of the following is a classic sign of hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Tachycardia
D. Bradycardia
Answer: C) Tachycardia
Rationale: Hyperthyroidism is characterized by an overproduction
of thyroid hormones, leading to symptoms like tachycardia, heat
intolerance, and weight loss.

3. What is the most common cause of secondary osteoporosis?
A. Calcium deficiency
B. Hyperparathyroidism
C. Long-term use of corticosteroids
D. Vitamin D deficiency
Answer: C) Long-term use of corticosteroids
Rationale: Long-term corticosteroid use is a major cause of
secondary osteoporosis due to its effect on bone metabolism,
leading to decreased bone density and increased fracture risk.

4. A patient with hypothyroidism is most likely to have which of

,the following symptoms?
A. Weight loss
B. Increased heart rate
C. Cold intolerance
D. Heat intolerance
Answer: C) Cold intolerance
Rationale: Hypothyroidism leads to reduced metabolism, causing
symptoms such as cold intolerance, weight gain, and fatigue.

5. Which of the following would you expect in a patient with
Addison’s disease?
A. Increased blood pressure
B. Hyperkalemia
C. Weight gain
D. Increased appetite
Answer: B) Hyperkalemia
Rationale: Addison’s disease, a disorder of the adrenal glands,
leads to decreased cortisol and aldosterone production. This
results in fluid and sodium loss and potassium retention, causing
hyperkalemia.

6. A patient with COPD has developed a barrel chest. What does
this physical finding indicate?
A. Emphysema
B. Pneumonia
C. Asthma
D. Acute bronchitis
Answer: A) Emphysema
Rationale: A barrel chest is a physical characteristic seen in
emphysema, a type of COPD. It occurs due to the hyperinflation
of the lungs, which causes the chest to assume a rounded,
expanded shape.

, 7. What is a common sign of a urinary tract infection (UTI) in
older adults?
A. Fever and chills
B. Confusion and delirium
C. Painful urination
D. Excessive thirst
Answer: B) Confusion and delirium
Rationale: In older adults, UTIs may present with atypical
symptoms such as confusion, delirium, or agitation, rather than
the typical symptoms of fever and dysuria.

8. A nurse is caring for a patient with hyperkalemia. What is the
most concerning sign of this condition?
A. Muscle weakness
B. Shortness of breath
C. Diarrhea
D. Nausea
Answer: A) Muscle weakness
Rationale: Hyperkalemia can cause muscle weakness and
potentially life-threatening arrhythmias due to its effect on the
electrical conductivity of the heart.

9. What is a classic symptom of Parkinson’s disease?
A. Muscle rigidity
B. Hypotension
C. Polyuria
D. Weight gain
Answer: A) Muscle rigidity
Rationale: Parkinson’s disease is characterized by symptoms such
as muscle rigidity, tremors, and bradykinesia due to a loss of
dopaminergic neurons in the brain.

10. A nurse is caring for a patient with pneumonia. Which of the

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