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Advanced Pathophysiology Q&A Bank – NURS

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Advanced Pathophysiology Q&A Bank – NURS

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1. What is a key characteristic of Crohn's disease?
A. Continuous inflammation of the colon
B. Painless, non-bloody diarrhea
C. Skip lesions along the gastrointestinal tract
D. Gallstone formation
Answer: C) Skip lesions along the gastrointestinal tract
Rationale: Crohn’s disease is characterized by inflammation that
can occur in patches (skip lesions) throughout the gastrointestinal
tract, leading to symptoms like diarrhea, abdominal pain, and
weight loss.

2. What is the main cause of type 2 diabetes?
A. Insulin resistance
B. Insulin deficiency
C. Autoimmune destruction of beta cells
D. Excessive glucagon secretion
Answer: A) Insulin resistance
Rationale: Type 2 diabetes is primarily caused by insulin
resistance, where the body’s cells do not respond effectively to
insulin, leading to elevated blood glucose levels.

3. A patient diagnosed with a brain tumor presents with sudden
weakness on one side of the body. What could this symptom
indicate?
A. Stroke
B. Seizure
C. Hemiparesis
D. Epilepsy
Answer: C) Hemiparesis
Rationale: Hemiparesis refers to weakness or partial paralysis on
one side of the body, which can occur with a brain tumor that

,affects the motor areas of the brain.

4. What condition is characterized by the failure of the heart to
pump effectively, leading to inadequate tissue perfusion?
A. Stroke
B. Coronary artery disease (CAD)
C. Heart failure
D. Hypertension
Answer: C) Heart failure
Rationale: Heart failure occurs when the heart is unable to pump
blood efficiently, leading to reduced perfusion of tissues and
organs.

5. A patient with COPD has developed a barrel chest. What does
this physical finding indicate?
A. Emphysema
B. Pneumonia
C. Asthma
D. Acute bronchitis
Answer: A) Emphysema
Rationale: A barrel chest is a physical characteristic seen in
emphysema, a type of COPD. It occurs due to the hyperinflation
of the lungs, which causes the chest to assume a rounded,
expanded shape.

6. A nurse is assessing a client with a suspected myocardial
infarction (MI). Which finding would be most indicative of an MI?
A. Severe sharp chest pain that radiates to the left shoulder
B. Shortness of breath with a productive cough
C. Gradual onset of bilateral lower leg edema
D. Sudden dizziness with no associated chest pain
Answer: A) Severe sharp chest pain that radiates to the left
shoulder

, Rationale: A common symptom of myocardial infarction is chest
pain that radiates to the left shoulder or arm. This is due to
ischemia affecting the heart muscle.

7. A patient with acute bacterial meningitis is likely to experience
which of the following?
A. Increased thirst and urination
B. Severe headache and neck stiffness
C. Joint pain and swelling
D. Abdominal pain and bloating
Answer: B) Severe headache and neck stiffness
Rationale: Acute bacterial meningitis causes inflammation of the
meninges, leading to symptoms like severe headache, neck
stiffness, photophobia, and fever.

8. What is a common complication of untreated hyperthyroidism?
A. Heart failure
B. Bradycardia
C. Hypoglycemia
D. Myxedema coma
Answer: A) Heart failure
Rationale: Untreated hyperthyroidism can lead to tachycardia and
increased cardiac workload, which can eventually result in heart
failure.

9. What is the primary cause of hypercapnia in patients with
chronic obstructive pulmonary disease (COPD)?
A. Increased carbon dioxide production
B. Airway obstruction
C. Pulmonary fibrosis
D. Decreased tidal volume
Answer: B) Airway obstruction
Rationale: In COPD, airway obstruction leads to difficulty in

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