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• NU 545 Verified Practice – Unit 5 Pathophysiology

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• NU 545 Verified Practice – Unit 5 Pathophysiology

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1. A patient with chronic kidney disease (CKD) is most at risk for
which of the following electrolyte imbalances?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypocalcemia
Answer: A) Hyperkalemia
Rationale: In CKD, the kidneys are unable to excrete potassium
effectively, leading to the accumulation of potassium in the blood,
resulting in hyperkalemia.

2. What is the primary cause of osteoarthritis?
A. Autoimmune reaction
B. Wear and tear on the joints
C. Bacterial infection
D. Vitamin D deficiency
Answer: B) Wear and tear on the joints
Rationale: Osteoarthritis is primarily caused by the degeneration
of cartilage due to repetitive use or aging, leading to joint pain
and stiffness.

3. A nurse is caring for a patient with hyperkalemia. What is the
most concerning sign of this condition?
A. Muscle weakness
B. Shortness of breath
C. Diarrhea
D. Nausea
Answer: A) Muscle weakness
Rationale: Hyperkalemia can cause muscle weakness and
potentially life-threatening arrhythmias due to its effect on the
electrical conductivity of the heart.

,4. What condition is characterized by the failure of the heart to
pump effectively, leading to inadequate tissue perfusion?
A. Stroke
B. Coronary artery disease (CAD)
C. Heart failure
D. Hypertension
Answer: C) Heart failure
Rationale: Heart failure occurs when the heart is unable to pump
blood efficiently, leading to reduced perfusion of tissues and
organs.

5. What is the primary cause of hypercapnia in patients with
chronic obstructive pulmonary disease (COPD)?
A. Increased carbon dioxide production
B. Airway obstruction
C. Pulmonary fibrosis
D. Decreased tidal volume
Answer: B) Airway obstruction
Rationale: In COPD, airway obstruction leads to difficulty in
exhaling CO2, resulting in the accumulation of carbon dioxide in
the bloodstream (hypercapnia).

6. What is the main cause of type 2 diabetes?
A. Insulin resistance
B. Insulin deficiency
C. Autoimmune destruction of beta cells
D. Excessive glucagon secretion
Answer: A) Insulin resistance
Rationale: Type 2 diabetes is primarily caused by insulin
resistance, where the body’s cells do not respond effectively to
insulin, leading to elevated blood glucose levels.

, 7. What is a key characteristic of Crohn's disease?
A. Continuous inflammation of the colon
B. Painless, non-bloody diarrhea
C. Skip lesions along the gastrointestinal tract
D. Gallstone formation
Answer: C) Skip lesions along the gastrointestinal tract
Rationale: Crohn’s disease is characterized by inflammation that
can occur in patches (skip lesions) throughout the gastrointestinal
tract, leading to symptoms like diarrhea, abdominal pain, and
weight loss.

8. A patient with a diagnosis of schizophrenia may experience
which of the following symptoms?
A. Auditory hallucinations
B. Extreme fatigue
C. Increased blood pressure
D. Chronic cough
Answer: A) Auditory hallucinations
Rationale: Schizophrenia is often associated with psychotic
symptoms, including auditory hallucinations, delusions, and
disorganized thinking.

9. Which of the following is a classic sign of hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Tachycardia
D. Bradycardia
Answer: C) Tachycardia
Rationale: Hyperthyroidism is characterized by an overproduction
of thyroid hormones, leading to symptoms like tachycardia, heat
intolerance, and weight loss.

10. What is a common complication of untreated

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