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• NURS 5350: Advanced Pathophysiology – 2025 Exam 3 Study Guide

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• NURS 5350: Advanced Pathophysiology – 2025 Exam 3 Study Guide

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1. A patient presents with fever, jaundice, and dark urine. Which
condition might this indicate?
A. Hepatitis
B. Gallstones
C. Pancreatitis
D. Cirrhosis
Answer: A) Hepatitis
Rationale: Hepatitis can lead to liver inflammation, resulting in
jaundice (yellowing of the skin), dark urine, and fever.

2. What is the primary cause of osteoarthritis?
A. Autoimmune reaction
B. Wear and tear on the joints
C. Bacterial infection
D. Vitamin D deficiency
Answer: B) Wear and tear on the joints
Rationale: Osteoarthritis is primarily caused by the degeneration
of cartilage due to repetitive use or aging, leading to joint pain
and stiffness.

3. What is the most common cause of peptic ulcers?
A. Stress
B. Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
C. Helicobacter pylori infection
D. Excessive alcohol consumption
Answer: C) Helicobacter pylori infection
Rationale: H. pylori infection is the leading cause of peptic ulcers
due to its ability to disrupt the mucosal lining of the stomach.

4. A patient with hypothyroidism is most likely to have which of
the following symptoms?

,A. Weight loss
B. Increased heart rate
C. Cold intolerance
D. Heat intolerance
Answer: C) Cold intolerance
Rationale: Hypothyroidism leads to reduced metabolism, causing
symptoms such as cold intolerance, weight gain, and fatigue.

5. What is a common sign of a urinary tract infection (UTI) in
older adults?
A. Fever and chills
B. Confusion and delirium
C. Painful urination
D. Excessive thirst
Answer: B) Confusion and delirium
Rationale: In older adults, UTIs may present with atypical
symptoms such as confusion, delirium, or agitation, rather than
the typical symptoms of fever and dysuria.

6. A patient with a history of chronic pancreatitis is at increased
risk for which of the following complications?
A. Diabetes mellitus
B. Hypoglycemia
C. Hyperkalemia
D. Asthma
Answer: A) Diabetes mellitus
Rationale: Chronic pancreatitis can damage the pancreas' ability
to secrete insulin, leading to insulin resistance and an increased
risk of diabetes mellitus.

7. A patient with cirrhosis has developed ascites. Which of the
following is a likely cause of ascites in this patient?
A. Decreased albumin production

, B. Increased clotting factors
C. Increased renin production
D. Decreased red blood cell production
Answer: A) Decreased albumin production
Rationale: In cirrhosis, the liver's ability to produce albumin is
impaired, leading to a decrease in plasma oncotic pressure, which
contributes to fluid accumulation in the abdomen (ascites).

8. A patient diagnosed with a brain tumor presents with sudden
weakness on one side of the body. What could this symptom
indicate?
A. Stroke
B. Seizure
C. Hemiparesis
D. Epilepsy
Answer: C) Hemiparesis
Rationale: Hemiparesis refers to weakness or partial paralysis on
one side of the body, which can occur with a brain tumor that
affects the motor areas of the brain.

9. A patient with diabetes mellitus presents with polyuria,
polydipsia, and weight loss. What condition might these
symptoms indicate?
A. Diabetic ketoacidosis (DKA)
B. Hyperosmolar hyperglycemic state (HHS)
C. Hypoglycemia
D. Hypertension
Answer: A) Diabetic ketoacidosis (DKA)
Rationale: DKA occurs when insulin deficiency causes increased
glucose production and fat breakdown, leading to ketosis and
elevated blood glucose levels, which cause symptoms like
polyuria, polydipsia, and weight loss.

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