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• Advanced Pathophysiology – NURS 5350 Test 3 2025 Questions

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• Advanced Pathophysiology – NURS 5350 Test 3 2025 Questions

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1. What is a common complication of untreated hyperthyroidism?
A. Heart failure
B. Bradycardia
C. Hypoglycemia
D. Myxedema coma
Answer: A) Heart failure
Rationale: Untreated hyperthyroidism can lead to tachycardia and
increased cardiac workload, which can eventually result in heart
failure.

2. What is a classic symptom of Parkinson’s disease?
A. Muscle rigidity
B. Hypotension
C. Polyuria
D. Weight gain
Answer: A) Muscle rigidity
Rationale: Parkinson’s disease is characterized by symptoms such
as muscle rigidity, tremors, and bradykinesia due to a loss of
dopaminergic neurons in the brain.

3. A patient with a history of gout presents with severe joint pain
in the big toe. What is the most likely cause of this pain?
A. Hyperuricemia
B. Osteoarthritis
C. Rheumatoid arthritis
D. Bone fracture
Answer: A) Hyperuricemia
Rationale: Gout is caused by the accumulation of uric acid crystals
in the joints, often beginning with the big toe. Elevated uric acid
levels (hyperuricemia) lead to these crystals forming and causing
intense pain.

,4. What is the primary cause of osteoarthritis?
A. Autoimmune reaction
B. Wear and tear on the joints
C. Bacterial infection
D. Vitamin D deficiency
Answer: B) Wear and tear on the joints
Rationale: Osteoarthritis is primarily caused by the degeneration
of cartilage due to repetitive use or aging, leading to joint pain
and stiffness.

5. Which of the following would you expect in a patient with
Addison’s disease?
A. Increased blood pressure
B. Hyperkalemia
C. Weight gain
D. Increased appetite
Answer: B) Hyperkalemia
Rationale: Addison’s disease, a disorder of the adrenal glands,
leads to decreased cortisol and aldosterone production. This
results in fluid and sodium loss and potassium retention, causing
hyperkalemia.

6. A nurse is assessing a client with a suspected myocardial
infarction (MI). Which finding would be most indicative of an MI?
A. Severe sharp chest pain that radiates to the left shoulder
B. Shortness of breath with a productive cough
C. Gradual onset of bilateral lower leg edema
D. Sudden dizziness with no associated chest pain
Answer: A) Severe sharp chest pain that radiates to the left
shoulder
Rationale: A common symptom of myocardial infarction is chest
pain that radiates to the left shoulder or arm. This is due to

, ischemia affecting the heart muscle.

7. What is the main cause of type 2 diabetes?
A. Insulin resistance
B. Insulin deficiency
C. Autoimmune destruction of beta cells
D. Excessive glucagon secretion
Answer: A) Insulin resistance
Rationale: Type 2 diabetes is primarily caused by insulin
resistance, where the body’s cells do not respond effectively to
insulin, leading to elevated blood glucose levels.

8. A patient is being treated for acute pancreatitis. What is a
common complication of this condition?
A. Renal failure
B. Chronic diarrhea
C. Hyperglycemia
D. Gallstones
Answer: A) Renal failure
Rationale: Acute pancreatitis can lead to systemic complications,
including renal failure, due to inflammation and the release of
digestive enzymes into the bloodstream.

9. A patient presents with fever, jaundice, and dark urine. Which
condition might this indicate?
A. Hepatitis
B. Gallstones
C. Pancreatitis
D. Cirrhosis
Answer: A) Hepatitis
Rationale: Hepatitis can lead to liver inflammation, resulting in
jaundice (yellowing of the skin), dark urine, and fever.

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