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BIO 202 Ch. 18 Part 2: Erythrocytes NUR 631 Week 4 Pathophysiology Exa
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What type of serological testing phenotyping
does the blood
bank technologist perform when
determining the
blood group of a patient?
If anti-K reacts 3+ with a donor Dosage
cell with a
genotype KK and 2+ with a Kk
cell, the antibody
is demonstrating:
Carla expresses the blood Gender and Race. The frequency of Duffy antigens Fya and Fyb
group antigens Fya, Fyb, and varies
Xga. James shows expressions of with race. The Fy(a−b−) phenotype occurs in almost
none of these antigens. What 70% of African Americans and is very rare in whites.
factor(s) may account for the The Xga antigen is X-linked and, therefore, expressed more
absence of these antigens in frequently in women (who may inherit the antigen from either
James? parent) than in men.
,Which of the following B. An individual with the BB genotype is
statements is true? homozygous for B antigen
A. An individual with the BO
genotype is
homozygous for B antigen
B. An individual with the BB
genotype is
homozygous for B antigen
C. An individual with the OO
genotype is
heterozygous for O antigen
D. An individual with the AB
phenotype is
homozygous for A and B
antigens
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Which genotype is A. DCe/dce
heterozygous for C?
A. DCe/dce
B. DCE/DCE
C. Dce/dce
D. DCE/dCe
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The Bombay phenotype will be expressed only when no H
substance is present. The Oh type is expressed by the genotype
Which genotype(s) will give rise hh. Bombays produce naturally occurring anti-H, and their serum
to the Bombay phenotype? agglutinates group
O red cells in addition to red cells from groups A, B, and AB
persons.
Meiosis in cell division is limited 1N. Meiosis involves two nuclear divisions in succession resulting
to the ova and sperm producing in four gametocytes each containing half the number of
four gametes containing what chromosomes found in somatic cells or 1N.
complement of DNA?
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Interphase, The cell is engaged in metabolic activity.
A cell that is not actively dividing Chromosomes are not clearly discerned; however, nucleoli may
is said to be in: be
visible
Which of the following Codominant
describes the expression of
most blood group antigens?
What blood type is not possible All are possible
for an offspring of an AO and
BO mating?
, The alleged father of a child in a -Indirect/secondary/second order
disputed case of paternity is An indirect/secondary/second order exclusion occurs when a
blood group AB. The mother is genetic marker is absent in the child but should have been
group O and the child is group transmitted by the alleged father. In this case, either A or B
O. What type of exclusion is should be present in the child.
this?
If the frequency of gene Y is 0.4 Linkage disequilibrium.
and the frequency of gene Z is Linkage disequilibrium is a phenomenon in which alleles situated
0.5, one would expect that they in close proximity on a chromosome associate with one another
should occur together 0.2 (20%) more than would be expected from individual allelic frequencies.
of the time. In actuality,
they are found together 32% of
the time. This is an example of:
In this type of inheritance, the Autosomal Dominant
father carries the trait on his X
chromosome. He has no sons
with the trait because he passed
his Y chromosome to his sons;
however, all his daughters will
express the trait.
In the Hardy-Weinberg formula p2 + 2pq + q2, p2 and q2
represent homozygous expressions and 2pq represents
In the Hardy-Weinberg formula,
heterozygous expression. This formula is
p2 represents:
used in population genetics to determine the frequency of
different alleles.
What is the Hardy-Weinberg p2 + 2pq + q2 = 1
formula?
Why do IgM antibodies, such as IgM antibodies are larger molecules and have the ability to bind
those formed against the ABO more antigen
antigens, have the ability to
directly agglutinate red blood
cells (RBCs) and cause visible
agglutination?
Which of the following LISS.
enhancement mediums LISS contains a reduced concentration of NaCl (0.2%) and results
decreases the zeta potential, in a reduction in charged ions within the ionic cloud, decreasing
allowing antibody and antigen the zeta potential and facilitating antigen and antibody
to come closer together? interaction.
Secondary.
An anamnestic response is a secondary immune response in
This type of antibody response
which memory lymphocytes respond rapidly to foreign antigen
is analogous to an anamnestic
in producing specific antibody. The antibodies are IgG and are
antibody reaction.
produced
at lower doses of antigen than in the primary response.
Which antibodies to a In the DAT (direct antiglobulin test), rabbit
component of complement are polyspecific antisera contains both an anti-human IgG
contained in the rabbit component and an antibody against the C3d component of
polyspecific antihuman globulin complement.
reagent for detection of in vivo
sensitization?
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