NSG 552 Psycho Pharmacology Wilkes Exam 3 2025 Study
Guide || correct answers 100%.
First Line Treatments for alcohol use disorder (according to Study Guide & Dynamed) correct
answers naltrexone and acamprosate
Second Line Treatments for alcohol use disorder (according to study guide but not dynamed)
correct answers Disulfuram and Bupropion (not FDA approved for ETOH but second line
according to study guide)
Second Line Treatment for alcohol use disorder (according to Dynamed) correct answers
Disulfuram
Other off label medications for alcohol use disorder according to Dynamed correct answers
Topiramate, gabapentin, baclofen
Other off label medications for alcohol use disorder according to Stahl's correct answers
Topiramate, ondansetron
MOA of Naltrexone correct answers Opioid Receptor Antagonist
MOA of Acamprosate correct answers - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram correct answers inhibits enzyme (aldehyde dehydrogenase) in the liver
, Bupropions role in alcohol use disorder correct answers Can diminish cravings for etoh, treat
underlying anxiety/depression
Safety Risk associated with bupropion and etoh correct answers bupropion increases the risk of
seizures in those going through etoh withdrawal
s/s ETOH intoxication correct answers impaired fine motor control, impaired judgement and
coordination, ataxic gait, poor balance, lethargy, difficulty sitting upright, difficulty with memory
and sitting upright, N/V, coma in levels 300mg/dL and over with respiratory depression and
death possible
S/S of etoh withdrawal correct answers Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption), hallucinations, Delirium Tremens
Delirium Tremens correct answers 48-96 hours after last etoh consumption includes anxiety,
anorexia, nausea/vomiting, psychomotor agitation
Scale used to measure etoh withdrawal correct answers CIWA
CIWA assesses: correct answers n/v, tremor, paroxysmall sweats, anxiety, agitation, tactile
disturbances, auditory disturbances, visual disturbances, headaches, orientation
CIWA scoring correct answers <10=mild
10-15=moderate
>15=severe
What medication is FDA approved for both opioid use disorder and alcohol use disorder? correct
answers Naltrexone
Guide || correct answers 100%.
First Line Treatments for alcohol use disorder (according to Study Guide & Dynamed) correct
answers naltrexone and acamprosate
Second Line Treatments for alcohol use disorder (according to study guide but not dynamed)
correct answers Disulfuram and Bupropion (not FDA approved for ETOH but second line
according to study guide)
Second Line Treatment for alcohol use disorder (according to Dynamed) correct answers
Disulfuram
Other off label medications for alcohol use disorder according to Dynamed correct answers
Topiramate, gabapentin, baclofen
Other off label medications for alcohol use disorder according to Stahl's correct answers
Topiramate, ondansetron
MOA of Naltrexone correct answers Opioid Receptor Antagonist
MOA of Acamprosate correct answers - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram correct answers inhibits enzyme (aldehyde dehydrogenase) in the liver
, Bupropions role in alcohol use disorder correct answers Can diminish cravings for etoh, treat
underlying anxiety/depression
Safety Risk associated with bupropion and etoh correct answers bupropion increases the risk of
seizures in those going through etoh withdrawal
s/s ETOH intoxication correct answers impaired fine motor control, impaired judgement and
coordination, ataxic gait, poor balance, lethargy, difficulty sitting upright, difficulty with memory
and sitting upright, N/V, coma in levels 300mg/dL and over with respiratory depression and
death possible
S/S of etoh withdrawal correct answers Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption), hallucinations, Delirium Tremens
Delirium Tremens correct answers 48-96 hours after last etoh consumption includes anxiety,
anorexia, nausea/vomiting, psychomotor agitation
Scale used to measure etoh withdrawal correct answers CIWA
CIWA assesses: correct answers n/v, tremor, paroxysmall sweats, anxiety, agitation, tactile
disturbances, auditory disturbances, visual disturbances, headaches, orientation
CIWA scoring correct answers <10=mild
10-15=moderate
>15=severe
What medication is FDA approved for both opioid use disorder and alcohol use disorder? correct
answers Naltrexone
