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BIO 669 Endocrine
BIO 669 Renal Structure
BIO 669 Endocrine
Insulin secretion is stimulated by elevated levels of: - ANSWER>>Glucose, amino acids
and GI hormones
*Insulin is an anabolic hormone and promotes the synthesis of proteins, lipids, and
nucleic acids
Amylin - ANSWER>>Delays nutrient uptake by reducing contractility into the stomach
and slowing the transit of nutrients from the stomach into the duodenum
*Decreases glucagon secretion
Insulin - ANSWER>>Cell growth and differentiation
Transport of glucose
Synthesis of fatty acids
Synthesis of protein
Synthesis of glycogen
Growth and survival of cells
Transport of amino acids and electrolytes
Glucagon - ANSWER>>Effects opposite to insulin
, *Stimulates glycogenolysis, gluconeogenesis, lipolysis
What is the hormone produced by the pancreas which inhibits both the action of insulin
and that of glucagon? - ANSWER>>Somatostatin
Outer portion of adrenal gland: - ANSWER>>Adrenal cortex (made of three zonas)
Zona Glomerulosa - ANSWER>>Aldosterone is produced
Zona Fasciculata - ANSWER>>biggest of layers in adrenal cortex and produces
cortisol
Zona Reticularis - ANSWER>>produces androgens
Adrenal Medulla - ANSWER>>Inner part of adrenal gland
*Innervated by the SNS and contains Chromaffin cells
What hormone stimulates the adrenal cortex? - ANSWER>>ACTH
Glucocorticoids (Cortisol) - ANSWER>>Direct effect on carbohydrate metabolism
Anti-inflammatory and growth-suppressing effects
*long-term secretion of cortisol can actually lead to connective tissue breakdown
Mineralocorticoids (Aldosterone) - ANSWER>>Increases the activity of the sodium
pump of the epithelial cells