Biochemistry Final Exam UNE CHEM 1005 Latest Update Questions and 100% Verified Correct Answers Guaranteed A+

Biochemistry Final Exam UNE CHEM 1005 Latest
Update 2025-2026 150 Questions and 100%
Verified Correct Answers Guaranteed A+

75% of amino acids liberated by degradation are... - CORRECT ANSWER: reutilized


ABC transporters - CORRECT ANSWER: assist in the transport of cholesterol and lipid
from the cells to HDL



ABCG1/ABCA1 Transporter - CORRECT ANSWER: on the cell surface and is
responsible for active transport of cholesterol and lipids out of the cell into the HDL
particle


Abetalipoproteinemia - CORRECT ANSWER: Loss of the ability to form lipoproteins
containing ApoB --> leads to loss of chylomicrons and VLDL



ACAT - CORRECT ANSWER: Acyl-coenzyme A acetyltransferase



Esterifies cholesterol within the cell


Acetyl-CoA is the source of... - CORRECT ANSWER: all carbons in cholesterol
synthesis



Allopurinol - CORRECT ANSWER: Inhibits xanthine oxidase


ApoCII - CORRECT ANSWER: Interacts with LPL (lipoprotein lipase) to activate the
enzyme

,*Transferred to chylomicrons and VLDL from HDL particles



ApoCII on Chylomicrons and on VLDLs interact with... - CORRECT ANSWER:
Lipoprotein lipase (LPL)



-this hydrolyzes TAGs into FFAs

-FFA are taken up by muscle (directly oxidized) or adipose (stored as TAGs)
-insulin enhances the activity of LPL



ApoE - CORRECT ANSWER: Apoprotein on chylomicrons and VLDL used for uptake by
the liver



*Transferred to chylomicrons and VLDL from HDL particles



ApoE on chylomicron remnants... - CORRECT ANSWER: facilitates uptake by the liver
SR-B1 receptor --> broken down into C, AA, and glycerol



ATP Mediated Protein Degradation - CORRECT ANSWER: proteins with short half-lives
or those that are misfolded are degraded in the cytosol. This requires ATP and ubiquitin.



Attachment of ubiquitin to protein... - CORRECT ANSWER: changes the confirmation of
a protein structure, targeting it to the proteasome



B12 role in amino acid metabolism (cobalamin) - CORRECT ANSWER: -required for
remethylation of homocysteine --> methionine by methionine synthase

-required for the conversion of methylmalonylCoA --> succinylCoA


B6 role in amino acid metabolism (pyridoxal phosphate) - CORRECT ANSWER: -
required for transamination reactions

, -required for the conversion of homocysteine --> cysteine by cystathionine beta-
synthase



B9 role in amino acid metabolism (folate) - CORRECT ANSWER: -folate cycle is
required to transfer a methyl group of B12 during the remethylation of homocysteine

-folate is a carbon carrier



Beta Oxidation - CORRECT ANSWER: Process of generating acetyl-CoA, NADH, and
FADH2 from the oxidation of FFAs taken up by peripheral tissues (mostly liver & skel.
muscle tissue).


Happens in mitochondria. Long chain FFAs cannot cross the mito membrane, so a
transport system is in place.



BH4 role in amino acid metabolism (tetrahydrobiopterin) - CORRECT ANSWER: -
required for metabolism of cyclic amino acids



Branched chain amino acids - CORRECT ANSWER: isoleucine, leucine, valine


Carbamoyl Phosphate Synthetase II (CPSII) role in pyrimidine synthesis - CORRECT
ANSWER: -the regulating step synthesizing carbamoyl phosphate from glutamine +
CO2 and ATP

-CPSII is activated by PRPP

-inhibited by UTP
-similar to the CPSI reaction in the urea cycle



CETP - CORRECT ANSWER: Cholesteryl ester transfer protein



Transfers cholesteryl ester from HDL to VLDL and transfers TG from VLDL to HDL