ONS Fundamentals of Chemotherapy
Immunotherapy Administration Exam
Questions with Expert Verified Answers
2025
Bone Marrow --- correct answer ---soft, sponge-like tissue in center of
most bones, produce WBC, RBC, and platelets.
Myelosuppression --- correct answer ---bone marrow activity is
decreased, causing less RBC, WBC and Platelets.
Myeloablation --- correct answer ---severe myelosuppression
Induction phase --- correct answer ---initial phase, typically in
hospital, intended myelosuppression
Consolidation phase (intensification/postremission therapy) ---
correct answer ---after successful induction, kills cancer cells left in
body (ex radiation, stem cell transplant)
,Synergy --- correct answer ---when one chemo drug helps another
work better at the same time
Complete response --- correct answer ---no identifiable cancer
present for at least one month or longer
Partial response --- correct answer ---Measurable tumor reduced by
50% for at least one month with no new tumors
Stable disease --- correct answer ---Tumor size reduced by less than
50% or less than 25% increase in growth
Progressive disease --- correct answer ---tumor growth more than
25% or new cancer
What are the phases of the cell cycle? --- correct answer ----G1 phase
-S phase
-G2 phase
-M phase
, What happens in G1 phase? --- correct answer ---The cell increases in
size and prepares to replicate its DNA.
What do chemo drugs do to target S phase? --- correct answer ---
Prevent cell from making DNA and/or RNA (replicating)
(ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines
(hydroxyurea))
What do chemo drugs do to target G2 phase? --- correct answer ---
Cells prepare to divide, chemo drugs stop development of elements
needed for cell division
(ex: topoisomerase I and II inhibitors, bleomycin)
What do chemo drugs do to target M phase? --- correct answer ---Cells
divide, drugs prevent cell division, including metaphase arrest or
microtubular disorganization
(ex: plant alkaloids and taxanes)
What are some examples of cell cycle non-specific drugs? --- correct
answer ---Active throughout the cell cycle:
-alkylating agents
-anthracycline antibiotics
Immunotherapy Administration Exam
Questions with Expert Verified Answers
2025
Bone Marrow --- correct answer ---soft, sponge-like tissue in center of
most bones, produce WBC, RBC, and platelets.
Myelosuppression --- correct answer ---bone marrow activity is
decreased, causing less RBC, WBC and Platelets.
Myeloablation --- correct answer ---severe myelosuppression
Induction phase --- correct answer ---initial phase, typically in
hospital, intended myelosuppression
Consolidation phase (intensification/postremission therapy) ---
correct answer ---after successful induction, kills cancer cells left in
body (ex radiation, stem cell transplant)
,Synergy --- correct answer ---when one chemo drug helps another
work better at the same time
Complete response --- correct answer ---no identifiable cancer
present for at least one month or longer
Partial response --- correct answer ---Measurable tumor reduced by
50% for at least one month with no new tumors
Stable disease --- correct answer ---Tumor size reduced by less than
50% or less than 25% increase in growth
Progressive disease --- correct answer ---tumor growth more than
25% or new cancer
What are the phases of the cell cycle? --- correct answer ----G1 phase
-S phase
-G2 phase
-M phase
, What happens in G1 phase? --- correct answer ---The cell increases in
size and prepares to replicate its DNA.
What do chemo drugs do to target S phase? --- correct answer ---
Prevent cell from making DNA and/or RNA (replicating)
(ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines
(hydroxyurea))
What do chemo drugs do to target G2 phase? --- correct answer ---
Cells prepare to divide, chemo drugs stop development of elements
needed for cell division
(ex: topoisomerase I and II inhibitors, bleomycin)
What do chemo drugs do to target M phase? --- correct answer ---Cells
divide, drugs prevent cell division, including metaphase arrest or
microtubular disorganization
(ex: plant alkaloids and taxanes)
What are some examples of cell cycle non-specific drugs? --- correct
answer ---Active throughout the cell cycle:
-alkylating agents
-anthracycline antibiotics
