Verified Solutions
What scale is used to quantitate COPD, and grade severity? -
ANSWER MRC breathlessness scale
People coinfected with what are at a high risk of developing TB
disease? - ANSWER HIV and M. Tuberculosis
When can TB be detected via TST or IGRA? - ANSWER 2-8
weeks
Persons with LTBI are not infectious? T/F - ANSWER True
Is a person with extrapulmonary TB disease ususally infectious?
- ANSWER no
What percentage of people with normal immunity will develop TB
disease after being infected? - ANSWER 10%
What is the highest risk factor of developing TB disease? -
ANSWER HIV and children <5
What two tests are used to detect TB? - ANSWER Mantoux TB
skin test and IGRAs (TB spot and Quantiferon Gold)
What is considered a wheal or raised area in a ppd test? -
ANSWER 6-10mm
A > or = to induration of 5mm on a ppd test is positive for who? -
ANSWER HIV, recent contacts of infectious TB, People with
fibrotic changes on a chest x-ray consistent with prior TB, or
organ transplant recipients and immunocompromised
, A > or = to induration of 10mm on a ppd test is positive for who? -
ANSWER Recent travel to prevalent countries, injection drug users,
residents and employees of high risk congregate settings (myobacterial lab
personnel), immunocompromised, children < 5 or children exposed to
adults at high risk
A > or = induration of 15mm on a ppd test is positive for who? -
ANSWER All persons with no known risk factors
Why is a 2-step TB test given? - ANSWER Used for initial skin test of
adults that will be retested periodically, to reduce the likelihood that a
boosted reaction will be misinterpretated as a recent infection
Is TST safe during pregnancy? - ANSWER yes
When should IGRA tb testing be done? - ANSWER In place of, but not in
addition to TST testing when concern for pt. returning to have TST read.
Not for children <5 unless in conjunction with TST
What are the symptoms of pulmonary TB? - ANSWER cough > 3 weeks,
hemoptysis, chest pain, weight loss, night sweats, fever, fatigue
What should be tested in any person suspected of having TB? How
should specimens be obtained? - ANSWER sputum cx; 3 different
specimens atleast 8 hours apart, one of which should be first thing in the
morning
What is the gold standard for diagnosing TB? - ANSWER
sputum culture
What is the treatment of choice for LTBI? - ANSWER Isoniazid 9
month daily regimen
What is the preferred medication for children ages 2-11 with
LTBI? - ANSWER Isoniazid
What are some serious adverse effects of Isoniazid? - ANSWER
peripheral neuropathy, fatal hepatitis, and elevated liver enzymes