Tech guru
Test Bank for Lippincott Illustrated Reviews:
Pharmacology 7th Edition by Karen Whalen
ALL CHAPTERS 1-48 WITH RATIONALES|A+GRADED
Te
ch
gu
1
ru
, Tech guru
Te
ch
gu
2
ru
, Tech guru
3.The nurse is teaching a patient who will be discharged home with a prescription for an enteric- coated
tablet. Which statement by the patient indicates understanding of the teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action. ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and disintegrate when
they reach the small intestine. There is usually some delay in onset of actions after taking these
medications. Enteric-coated tablets should not be crushed or chewed, which would alter the time and
location of absorption. Acidic foods will not enhance the absorption of the medication. The patient should
not to eat high-fat food before ingesting an enteric-coated tablet, because high-fat foods decrease the
absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP: NURSING PROCESS: Nursing
Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4.A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be given by
subcutaneous injection instead of by mouth. The nurse will explain that this is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects. ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by digestive
enzymes and must be given parenterally. Because insulin is destroyed by digestive enzymes, it would not
make it to the liver for metabolism with a first-pass effect. Subcutaneous tissue has fewer blood vessels,
so absorption is slower in such tissue. Insulin is given subcutaneously because it is desirable to have it
absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3 TOP: NURSING PROCESS:
Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Te
5.The nurse is preparing to administer an oral medication that is water-soluble. The nurse understands that
this drug
ch
a. must be taken on an empty stomach.
gu
3
ru
, Tech guru
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal tract. ANS: B
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4 TOP: NURSING PROCESS:
Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
6.A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment. How will
the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food ANS: C
Food can stimulate the production of gastric acid so medications requiring an acidic environment should
be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4 TOP: NURSING PROCESS: Nursing
Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
7.The nurse is preparing an injectable drug and wants to administer it for rapid absorption. How will the
nurse give this medication?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper arm ANS: A
Drugs given IM are absorbed faster in muscles that have more blood vessels, such as the deltoid, rather
than those with fewer blood vessels, such as the gluteals. Subcutaneous routes are used when absorption
Te
needs to be slower and more sustained.
ch
gu
4
ru
Test Bank for Lippincott Illustrated Reviews:
Pharmacology 7th Edition by Karen Whalen
ALL CHAPTERS 1-48 WITH RATIONALES|A+GRADED
Te
ch
gu
1
ru
, Tech guru
Te
ch
gu
2
ru
, Tech guru
3.The nurse is teaching a patient who will be discharged home with a prescription for an enteric- coated
tablet. Which statement by the patient indicates understanding of the teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action. ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and disintegrate when
they reach the small intestine. There is usually some delay in onset of actions after taking these
medications. Enteric-coated tablets should not be crushed or chewed, which would alter the time and
location of absorption. Acidic foods will not enhance the absorption of the medication. The patient should
not to eat high-fat food before ingesting an enteric-coated tablet, because high-fat foods decrease the
absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP: NURSING PROCESS: Nursing
Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4.A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be given by
subcutaneous injection instead of by mouth. The nurse will explain that this is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects. ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by digestive
enzymes and must be given parenterally. Because insulin is destroyed by digestive enzymes, it would not
make it to the liver for metabolism with a first-pass effect. Subcutaneous tissue has fewer blood vessels,
so absorption is slower in such tissue. Insulin is given subcutaneously because it is desirable to have it
absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3 TOP: NURSING PROCESS:
Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Te
5.The nurse is preparing to administer an oral medication that is water-soluble. The nurse understands that
this drug
ch
a. must be taken on an empty stomach.
gu
3
ru
, Tech guru
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal tract. ANS: B
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4 TOP: NURSING PROCESS:
Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
6.A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment. How will
the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food ANS: C
Food can stimulate the production of gastric acid so medications requiring an acidic environment should
be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4 TOP: NURSING PROCESS: Nursing
Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
7.The nurse is preparing an injectable drug and wants to administer it for rapid absorption. How will the
nurse give this medication?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper arm ANS: A
Drugs given IM are absorbed faster in muscles that have more blood vessels, such as the deltoid, rather
than those with fewer blood vessels, such as the gluteals. Subcutaneous routes are used when absorption
Te
needs to be slower and more sustained.
ch
gu
4
ru
