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,Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
xc xc xc xc xc xc xc xc xc
the expected effect for this prescription?
xc xc xc xc xc xc
A. Curative effect on symptoms xc x c xc
B. Systemic effect on symptoms xc xc xc
C. Local effect on symptoms xc xc xc
D. Parenteral effect on symptoms xc xc xc
ANS: B x c x c
Rationale: Drugs that produce systemic effects are taken into the body, circulated
x c x c x c x c x c x c xc x c xc x c x c
throug h the bloodstream to their sites of action in various body tissues, and
x c xc xc x c x c x c xc x c x c x c x c x c xc x c
eventually eliminat ed from the body. Curative agents are given to cure a disease process. In
x c x c xc xc xc xc xc xc xc xc xc xc xc xc xc xc
this case, paro xetine hydrochloride will control the symptoms but not cure the disorder.
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
Drugs with loca l effects, such as sunscreen and local anesthetics, act mainly at the site of
xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc
application. Pa roxetine hydrochloride is not administered parenterally. Parenteral agents
xc xc xc xc xc xc xc xc xc xc
are administere d subcutaneously, intramuscularly, or intravenously.
xc xc xc xc xc xc xc
PTS: 1 REF: p. 3, Introduction OBJ: 1 xc x c
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Understand
x c x c NOT: Multiple Choice xc x c x c x c xc
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
xc
.hCaOt Mi s another name for this type
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o f medication?
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A. Synthetic drug xc
B. Semisynthetic drug xc
C. Biotechnology drug xc
D. Prototype drug xc
ANS: B x c x c
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
xc xc xc xc xc xc xc xc xc
that have been chemically modified. Synthetic drugs are more standardized in their chemi cal
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
characteristics, more consistent in their effects, and less likely to produce allergic rea
xc xc xc xc xc xc xc xc xc xc xc xc xc
ctions. Biotechnology drugs involve manipulating DNA and RNA and recombining gene
xc xc xc xc xc xc xc xc xc xc xc
s into hybrid molecules that can be inserted into living organisms. Prototype drugs are th
xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc
e first drug of a particular group to be developed.
xc xc xc xc x c x c x c x c x c x c
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 xc xc xc
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Understand
x c x c NOT: Multiple Choice xc x c x c x c xc
3. Which classification applies to morphine?
xc xc xc xc
A. Central nervous system depressant xc xc xc
B. Central nervous system stimulant xc xc xc
, C. Anti-inflammatory
D. Antihypertensive
ANS: A x c x c
Rationale: Drugs are classified according to their effects on particular body systems,
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thei r therapeutic uses, and their chemical characteristics. Morphine is classified as a
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central nervous system depressant and will produce this effect in the client. A
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central nervous s ystem stimulant increases attention and raises mood. An anti-
xc xc xc xc xc xc xc xc xc xc xc xc
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
xc xc xc xc xc xc xc xc xc xc xc xc
antihypertensive agent reduces blood pressure.
xc xc xc xc xc
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
xc xc xc xc xc x c
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Remember x c NOT: Multiple Choice
x c xc xc x c x c xc
4. A client is administered amoxicillin. The generic name of this medication belongs to whi
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ch drug group?
xc xc xc
A. Selective serotonin reuptake inhibitors xc xc xc
B. Diuretics
C. Penicillins
D. ACE inhibitors xc
ANS: C x c x c
Rationale: The generic n a mGeR oAfD
t eEn Si nBdOicOa tSe T
xc s .
t hCe Od r u g group (e.g., drugs with generic
xc xc m xci i mi i x c xc xc x c xc
na mes ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
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medicat
xc
ions that have antidepressant effects; SSRI is a broad classification, not a generic name. D
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iuretics are medications that increase urine output; diuretic is a broad classification, not a
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generic name. ACE inhibitor is the broad classification for the angiotensin receptor block ers,
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not the generic name.
xc xc xc xc
PTS: 1 REF: p. 3, Drug Names OBJ: 2 xc xc xc
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Understand
x c NOT: Multiple Choice
x c xc x c x c x c xc
5. The administration of diphenhydramine is regulated by which U.S. government agency?
xc xc xc xc xc xc xc xc x c xc
A. Public Health Service xc xc
B. Federal Trade Commission xc xc
C. Occupational Safety and Health Administration xc xc xc xc
D. Food and Drug xc x c
Administration ANS:
xc xc D
,
xc xc xc xc xc xc xc xc xc xc
,Chapter 1, The Foundation of Pharmacology: Quality and Safety
xc xc xc xc xc xc xc xc
1. A woman diagnosed with obsessive–
xc xc xc xc
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
xc xc xc xc xc xc xc xc xc
the expected effect for this prescription?
xc xc xc xc xc xc
A. Curative effect on symptoms xc x c xc
B. Systemic effect on symptoms xc xc xc
C. Local effect on symptoms xc xc xc
D. Parenteral effect on symptoms xc xc xc
ANS: B x c x c
Rationale: Drugs that produce systemic effects are taken into the body, circulated
x c x c x c x c x c x c xc x c xc x c x c
throug h the bloodstream to their sites of action in various body tissues, and
x c xc xc x c x c x c xc x c x c x c x c x c xc x c
eventually eliminat ed from the body. Curative agents are given to cure a disease process. In
x c x c xc xc xc xc xc xc xc xc xc xc xc xc xc xc
this case, paro xetine hydrochloride will control the symptoms but not cure the disorder.
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
Drugs with loca l effects, such as sunscreen and local anesthetics, act mainly at the site of
xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc
application. Pa roxetine hydrochloride is not administered parenterally. Parenteral agents
xc xc xc xc xc xc xc xc xc xc
are administere d subcutaneously, intramuscularly, or intravenously.
xc xc xc xc xc xc xc
PTS: 1 REF: p. 3, Introduction OBJ: 1 xc x c
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Understand
x c x c NOT: Multiple Choice xc x c x c x c xc
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
xc xc xc xc xc xc xc xc xc xc xc xc
substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
xc
.hCaOt Mi s another name for this type
xc xc xc mi xc x c xc xc xc xc
o f medication?
xc xc xc
A. Synthetic drug xc
B. Semisynthetic drug xc
C. Biotechnology drug xc
D. Prototype drug xc
ANS: B x c x c
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
xc xc xc xc xc xc xc xc xc
that have been chemically modified. Synthetic drugs are more standardized in their chemi cal
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
characteristics, more consistent in their effects, and less likely to produce allergic rea
xc xc xc xc xc xc xc xc xc xc xc xc xc
ctions. Biotechnology drugs involve manipulating DNA and RNA and recombining gene
xc xc xc xc xc xc xc xc xc xc xc
s into hybrid molecules that can be inserted into living organisms. Prototype drugs are th
xc xc xc xc xc xc xc xc xc xc xc xc xc xc xc
e first drug of a particular group to be developed.
xc xc xc xc x c x c x c x c x c x c
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 xc xc xc
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Understand
x c x c NOT: Multiple Choice xc x c x c x c xc
3. Which classification applies to morphine?
xc xc xc xc
A. Central nervous system depressant xc xc xc
B. Central nervous system stimulant xc xc xc
, C. Anti-inflammatory
D. Antihypertensive
ANS: A x c x c
Rationale: Drugs are classified according to their effects on particular body systems,
xc xc xc xc xc xc xc xc xc xc xc
thei r therapeutic uses, and their chemical characteristics. Morphine is classified as a
xc xc xc xc xc xc xc xc xc xc xc xc xc
central nervous system depressant and will produce this effect in the client. A
xc xc xc x c xc x c xc x c x c x c x c xc x c
central nervous s ystem stimulant increases attention and raises mood. An anti-
xc xc xc xc xc xc xc xc xc xc xc xc
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
xc xc xc xc xc xc xc xc xc xc xc xc
antihypertensive agent reduces blood pressure.
xc xc xc xc xc
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
xc xc xc xc xc x c
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Remember x c NOT: Multiple Choice
x c xc xc x c x c xc
4. A client is administered amoxicillin. The generic name of this medication belongs to whi
xc xc xc xc xc xc xc xc xc xc xc xc xc
ch drug group?
xc xc xc
A. Selective serotonin reuptake inhibitors xc xc xc
B. Diuretics
C. Penicillins
D. ACE inhibitors xc
ANS: C x c x c
Rationale: The generic n a mGeR oAfD
t eEn Si nBdOicOa tSe T
xc s .
t hCe Od r u g group (e.g., drugs with generic
xc xc m xci i mi i x c xc xc x c xc
na mes ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
xc xc xc xc xc xc xc x c xc xc xc xc
medicat
xc
ions that have antidepressant effects; SSRI is a broad classification, not a generic name. D
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
iuretics are medications that increase urine output; diuretic is a broad classification, not a
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
generic name. ACE inhibitor is the broad classification for the angiotensin receptor block ers,
xc xc xc xc xc xc xc xc xc xc xc xc xc xc
not the generic name.
xc xc xc xc
PTS: 1 REF: p. 3, Drug Names OBJ: 2 xc xc xc
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
x c xc xc xc xc xc xc
Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
xc xc xc x c x c x c x c x c x c xc
Safety KEY: Integrated Process: Nursing Process
x c xc x c xc xc xc
BLM: Cognitive Level: Understand
x c NOT: Multiple Choice
x c xc x c x c x c xc
5. The administration of diphenhydramine is regulated by which U.S. government agency?
xc xc xc xc xc xc xc xc x c xc
A. Public Health Service xc xc
B. Federal Trade Commission xc xc
C. Occupational Safety and Health Administration xc xc xc xc
D. Food and Drug xc x c
Administration ANS:
xc xc D
,
