2025/VERIFIED
B
The PMHNP is evaluating a 68-year-old man for symptoms of major depression. While
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assessing the appearance of the patient, an obvious left-sided ptosis is noted. Which
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cranial nerve is directly linked to this condition?
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a. III
b. IV
c. V
d. VI - A B BB B BB
A 55-year-old woman has been referred for a psychiatric evaluation for a change in
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personality, lack of impulse control, and increasingly reckless decision-making. Which
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area of the brain would be responsible for these symptoms?
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a. Parietal lobe B BB
b. Broca's area B BB
c. Wernicke's area B BB
d. Frontal lobe - D B BB B BB B BB
A patient was recently started on a dopamine antagonist, and complains of breast
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tenderness and a milky discharge. What is the most likely explanation for these
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symptoms?
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a. Dopamine transmission in the nigrostriatal pathway B BB B BB B BB B BB B BB
b. Dopamine transmission in the tuberoinfundibular pathway B BB B BB B BB B BB B BB
c. Dopamine transmission in the mesolimbic pathway B BB B BB B BB B BB B BB
d. Dopamine increases throughout the basal ganglia - B B BB B BB B BB B BB B BB B BB B BB
A patient who was recently started on haloperidol for psychosis begins to manifest hand
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tremor, and a shuffling gait. What is the most likely explanation for these
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symptoms?
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a. Dopamine transmission in the nigrostriatal pathway B BB B BB B BB B BB B BB
b. Dopamine transmission in the tuberoinfundibular pathway B BB B BB B BB B BB B BB
c. Dopamine transmission in the mesolimbic pathway B BB B BB B BB B BB B BB
d. Dopamine increases throughout the basal ganglia - A B BB B BB B BB B BB B BB B BB B BB
A 72-year-old man with a comorbid history of uncontrolled hypertension is referred to
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the PMHNP for dementia secondary to depression. The mental status exam reveals
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difficulty speaking fluently, inappropriate and confabulated responses, incongruent affect,
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and poor judgment. A cerebrovascular accident in which region of the brain would better
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explain these symptoms?
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a. Parietal lobe B BB
b. Wernicke's area B BB
c. Broca's area B BB
d. Occipital lobe - C B BB B BB B BB
Which region of the brain is associated with sensory integration, spatial awareness, and
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conscious awareness of the opposite side of the body?
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a. Occipital lobe B BB
b. Wernicke's area B BB
c. Broca's area B BB
,d. Parietal lobe - D B BB B BB B BB
A patient appears internally preoccupied and responding to auditory hallucination. This
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patient may have a pathology affecting which lobe of the brain?
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a. Temporal lobe B BB
b. Occipital lobe B BB
c. Parietal lobe B BB
d. Cerebellum - A B BB B BB
A patient presents with atypical symptoms of psychosis that include inconsistent
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auditory hallucinations without disorganization. What is the best definition of an EEG
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and its utility?
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a. Radiologic test utilizing magnets and radio waves to provide a detailed image
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of the structures of the brain
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b. Electrophysiologic test that depicts electrical activity on the surface of the brain B BB B BB B BB B BB B BB B BB B BB B BB B BB B BB B BB
c. A serum test to indicate nutritional deficiencies that inhibit the
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formation of neurotransmitters
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d. A neuropsychological test to distinguish psychosis from a psychosomatic illness. - B
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Neurons that only travel from the body to the brain are called:
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a. Sensory neurons B BB
b. Motor neurons B BB
c. Inter neurons B BB
d. Astrocytes - A B BB B BB
The part of the neuron that takes in and receives messages is called:
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a. Dendrite
b. Axon
c. Synapse
d. Node of Ranvier - A B BB B BB B BB B BB
What is the fatty layer that prevents interference and increases the speed of impulse
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transmission along the axon?
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a. Dendrite
b. Axon
c. Synapse
d. Myelin sheath - D B BB B BB B BB
Which of the following receives messages and conducts impulses to the soma?
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a. Dendrite
b. Axon
c. Synapse
d. Myelin sheath - A B BB B BB B BB
The junction between two neurons is known as the:
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a. Dendrite
b. Node of Ranvier B BB B BB
c. Synapse
d. Soma - C B BB B BB
,When explaining the means by which neurotransmitters relate to mental illness, a patient
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ask, "What is a neurotransmitter?" The best answer is:
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a. A fatty layer covering the axon
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b. A chemical messenger
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c. A nerve cell B BB B BB
d. The space between nerve cells - B
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A patient is diagnosed with major depressive disorder with the most prominent feature
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of apathy, anhedonia, and isolation. Which neurotransmitter is associated with the
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symptoms?
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a. Serotonin
b. Gamma-amino benzoic acid (GABA) B BB B BB B BB
c. Dopamine
d. Cannabinoids - C B BB B BB
The PMHNP prescribes fluoxetine to treat depression. Which neurotransmitter will be
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made readily available in the synapse?
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a. Dopamine
b. Serotonin
c. Gamma-amino benzoic acid (GABA) B BB B BB B BB
d. Acetylcholine - B B BB B BB
The PMHNP in the ED is evaluating a 68-year-old woman who was recently diagnosed
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with mild cognitive impairment and cannot remember the name of the medication that
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she has recently started 1 week ago. The patient is complaining of increased heart rate,
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sweating, and muscle spasms progressively worsening for the last 3 days. Which
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neurotransmitter is associated with this adverse effect?
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a. Serotonin
b. Acetylcholine
c. Gamma-amino benzoic acid (GABA) B BB B BB B BB
d. Dopamine - B B BB B BB
Which of the following neurotransmitters exert inhibition over neuronal function?
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a. Acetylcholine
b. Cannabinoids
c. Gamma-amino benzoic acid (GABA) B BB B BB B BB
d. Dopamine - C B BB B BB
A patient with alcohol use disorder is admitted for detox in anticipation of admission
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to an inpatient rehabilitation facility. The patient takes metoprolol for hypertension,
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which he has forgotten to take today, and his last drink was 72 hours ago. Which tool
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should the PMHNP use to evaluate for symptoms of withdrawal?
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a. Hamilton Rating Scale for Depression B BB B BB B BB B BB
b. Clinical Institute Withdrawal Assessment B BB B BB B BB
c. Vital signs B BB
d. Quick Inventory of Depressive Symptomatology - B
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A 45-year-old man presents for a follow-up visit after starting on an SSRI 2 weeks ago
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for major depressive disorder. Which assessment tool would be the best indicator of
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progress?
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a. Geriatric Depression Scale B BB B BB
b. The Young Mania Rating Scale
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, c. Yale-Brown Obsessive Compulsive Scale B BB B BB B BB
d. Quick Inventory of Depressive Symptomatology - D
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The PMHNP knows that the study of how the body absorbs, distributes, metabolizes, and
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excretes a medication is known as:
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a. Breakdown
b. Pharmacokinetics
c. Pharmacodynamics
d. First-pass effect - B B BB B BB B BB
After a drug is absorbed the substrate binds to protein for transport. Which portion of
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the drug is available for therapeutic effects?
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a. Bound
b. Unbound
c. Metabolized
d. Excreted - B B BB B BB
A 19-year-old male is referred to the PMHNP by the student health office for
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alcohol use disorder. The patient states that on one occasion he passed out much
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sooner than he usually would with far less than he would usually drink. Upon further
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interview, the patient reveals the time he passed out was during a fraternity hazing
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in which he was butt- chugging (receiving a beer and vodka enema). What
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pharmacokinetic process was bypassed by this rectal administration route?
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a. Excretion
b. Absorption
c. Distribution
d. First-pass effect - D B BB B BB B BB
The PMHNP is monitoring a serum drug level for a medication with a 24-hour half-life.
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How many hours will it take to reach steady state?
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a. 48hours
b. 72hours
c. 96hours
d. 120hours - D B BB B BB
A patient with schizophrenia was discharged from the hospital on olanzapine 5 mg
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twice a day. He immediately resumed smoking cigarettes and escalated to one pack
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per day. Upon presenting for his 1- week follow-up appointment, the patient reports
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he is having trouble sleeping and the voices have started to return. Which of the
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following actions should the PMHNP take?
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a. Send the patient to the ED for stabilization
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b. Change to another antipsychotic medication, and refer to a psychiatrist
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c. Increase his olanzapine, and schedule a follow-up visit in 2
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days Tell him to stop smoking and give him a nicotine
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patch - C
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A patient who has been stable on quetiapine (Seroquel XR) for 3 months has decided
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to start to drink grapefruit juice twice daily because she has heard it helps with
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weight loss. She calls to report that since her new diet she has been feeling fatigue
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and difficulty waking up in the morning. What is the best response by the PMHNP?
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a. "I will put in a new prescription for a lower dose of your medication."
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