Medication Quiz well answered to pass
Antidepressants - correct answer ✔✔Do not cause dependance, tolerance or addiction. C/I in
bipolar disorder (exacerbates mania). Some induce anticholinergic side effects. Can increase
suicidal thinking especially in the beginning of treatment. Take 2-6 weeks to start working,
dendrites and axons have to begin to regrow in the brain.
Tricyclic Antidepressants (TCAs) - correct answer ✔✔Common side effects include weight gain
and anticholinergic effects. More serious adverse effects can be cardio-toxicity and orthostatic
hypotension.
TCA drugs - correct answer ✔✔Amitriptyline (Elavil)
*Clomiprimine (Anafranil):* Also used for anorexia and OCD
Imipramine (Tofranil)
Monoamine Oxidase Inhibitors (MAOIs) - correct answer ✔✔Elevates serotonin, dopamine and
norepinephrine levels. Hypertensive crisis can result from interactions with food and other
meds. Because these foods contain *Tyramine* patients must avoid aged cheese, processed
meats, beer, red wine, raisins, avocados, figs, bananas, caffeine and chocolate.
MAOI drugs - correct answer ✔✔Phenelzine sulfate (Nardil)
Selegiline (Emsam) Transdermal Patch - bypasses the stomach, doesn't have food
restrictions/interactions
Serotonin Selective Reuptake Inhibitors (SSRIs) - correct answer ✔✔Elevates serotonin levels.
Safer antidepressants (2-3 month supply usually not lethal), less side effects, no food
restrictions; biggest problem is that they may interfere with *sexual performance and libido*.
Weight gain may be experienced.
, SSRI drugs - correct answer ✔✔fluoxetine (Prozac)
*paroxetine (Paxil)*
sertraline (Zoloft)
citalopram (Celexa)
escitalopram (Lexapro)
Atypical Antidepressant drugs - correct answer ✔✔desvenlafaxine (Prestiq)
duloxetine (Cymbalta)
venlafaxine (Effexor)
bupropion (Wellbutrin)
mirtazapine (Remeron)
trazodone
bupropion (Wellbutrin) - correct answer ✔✔Antidepressant, works on dopamine and
norepinephrine. Fewer sexual side effects and lower risk of weight gain, also works on
controlling *nicotine addiction*.
trazodone - correct answer ✔✔Antidepressant that is really only *used for sleep* in patients
who have insomnia, in rare cases *priapism* (prolonged erection) may develop.
Serotonin Syndrome - correct answer ✔✔Potentially fatal condition from elevated levels of
serotonin in the blood. S/S: *fever*, tachycardia, hypertension, sweating, shivering, confusion,
anxiety, restlessness, disorientation, tremors, muscular spasms, and rigidity. Risk factors are a
combined use of SSRI with other antidepressants or St. John's Wort, or inadequate time
between discontinuing one antidepressant and initiating another.