Kidney Transplantation 2025/2026 Exam
Questions and Answers | 100% Pass
1
What subset of patients (status and GFR) are potentially acceptable
candidates for transplantation? - 🧠 ANSWER ✔✔Patients with CKD and a
GFR less than or equal to 20 mL/min
What are five absolute contraindications to kidney transplantation? - 🧠
ANSWER ✔✔1. active malignancy (except skin cancer)
2. acute infection (e.g. osteomyelitis, HIV w/measurable viral load, active
HBV/HCV, etc)
3. chronically active systemic diseases (e.g. SLE, vasculitis, cirrhosis)
4. active substance abuse
5. immunological problems (i.e. donor/recipient mismatch)
What are some relative contraindications to kidney transplantation? - 🧠
ANSWER ✔✔Advanced cardiopulmonary disease, extensive PVD, severe
chronic liver disease, morbid obesity, uncontrolled psychiatric disorder, HIV
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
, w/unmeasurable viral load, any chronic illness with a life expectancy of less
than 5 years
2
What are three major preoperative immunological considerations? - 🧠
ANSWER ✔✔1. ABO compatibility
2. HLA compatibility
3. Sensitization to HLA antigens
What is likely to happen if an ABO incompatible donor kidney is
transplanted? - 🧠 ANSWER ✔✔Hyperacute rejection due to preformed
antibodies
What are the three major HLA antigens measured in transplantation and
which is the most important to match? - 🧠 ANSWER ✔✔A, B, and DR. DR
seems to be the most important. (Note: each individual has two alleles of
each of these, so there are a total of *six* antigens to match)
What are panel reactive antibodies (PRA)? - 🧠 ANSWER ✔✔This is a lab
test done with patient serum in which it is screened against a panel of
known HLA-typed cells to measure reaction. A highly negative PRA
indicates that a patient is less likely to have a reaction to a donor kidney,
while a high PRA is predictive of a less favorable outcome.
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
Questions and Answers | 100% Pass
1
What subset of patients (status and GFR) are potentially acceptable
candidates for transplantation? - 🧠 ANSWER ✔✔Patients with CKD and a
GFR less than or equal to 20 mL/min
What are five absolute contraindications to kidney transplantation? - 🧠
ANSWER ✔✔1. active malignancy (except skin cancer)
2. acute infection (e.g. osteomyelitis, HIV w/measurable viral load, active
HBV/HCV, etc)
3. chronically active systemic diseases (e.g. SLE, vasculitis, cirrhosis)
4. active substance abuse
5. immunological problems (i.e. donor/recipient mismatch)
What are some relative contraindications to kidney transplantation? - 🧠
ANSWER ✔✔Advanced cardiopulmonary disease, extensive PVD, severe
chronic liver disease, morbid obesity, uncontrolled psychiatric disorder, HIV
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
, w/unmeasurable viral load, any chronic illness with a life expectancy of less
than 5 years
2
What are three major preoperative immunological considerations? - 🧠
ANSWER ✔✔1. ABO compatibility
2. HLA compatibility
3. Sensitization to HLA antigens
What is likely to happen if an ABO incompatible donor kidney is
transplanted? - 🧠 ANSWER ✔✔Hyperacute rejection due to preformed
antibodies
What are the three major HLA antigens measured in transplantation and
which is the most important to match? - 🧠 ANSWER ✔✔A, B, and DR. DR
seems to be the most important. (Note: each individual has two alleles of
each of these, so there are a total of *six* antigens to match)
What are panel reactive antibodies (PRA)? - 🧠 ANSWER ✔✔This is a lab
test done with patient serum in which it is screened against a panel of
known HLA-typed cells to measure reaction. A highly negative PRA
indicates that a patient is less likely to have a reaction to a donor kidney,
while a high PRA is predictive of a less favorable outcome.
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
