ADVANCED PATHOPHYSIOLOGY UTMB 5355 EXAM 2 QUESTIONS AND CORRECTLY VERIFIED ANSWERS 2024

ADVANCED PATHOPHYSIOLOGY UTMB 5355 EXAM 2 QUESTIONS AND CORRECTLY VERIFIED ANSWERS 2024 When inflammation is systemic - induces fever and cytokines production – Correct Answer TNF-a In severe sepsis_ can induce cachexia and thrombosis – Correct Answer TNF-a chemotactic factors – Correct Answer Attracts and directs leukocytes to the area of inflammation nitric oxide – Correct Answer potent vasodilator that maintains vascular tone, blood flow, blood pressure and inhibits platelet activation Relationship between T cell function & interleukins – Correct Answer Interleukins are secreted by different types of leukocytes. Regulate innate and adaptive immune systems. 2 types of T cells – Correct Answer cytotoxic T cells and helper T cellsCytotoxic T cells – Correct Answer directly kills cells that are infected with virus or pathogen Helper T cells – Correct Answer help to stimulate the response of other cells mainly macrophages, B cells and cytotoxic T cells- release interleukins which stimulate B cells Example of helper t Cell – Correct Answer CD4, most prolific cytokine producer Immune system distinguishes Two groups of foreign substances Which are – Correct Answer antigens/MHC self cells 2 types of immune responses – Correct Answer humoral and cell mediated humoral immune response – Correct Answer The branch of acquired immunity that involves the activation of B cells and that leads to the production of antibodies, immunoglobulins, either neutralize or eliminate pathogenscell-mediated immunity – Correct Answer involves T cells and responds to any cells that displays MHC markers Steps in cell-mediated immune response – Correct Answer 1. self cells or APCs display foreign antigens and bind to T cells 2. Interleukins activate T cells 3. If MHC are displayed on plasma membrane T cells proliferate p