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NU606/ NU 606 EXAM 2 () ADVANCED PATHOPHYSIOLOGY GUIDE 90+ QUESTIONS WITH CORRECT VERIFIED ANSWERS || GUARANTEED PASS || NEWEST VERSION

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Which of the following is known to affect pupillary reflex? A. Opiate usage B. Damage to CN II C. Infection of the uveal tract D. Increase in intraocular pressure - ANSWER A. Opiate usage Infectious conjunctivitis - ANSWER Hyperacute -abrupt onset, yellow-green drainage -severe sight-threatening ocular infection -more likely caused by gonorrhea, less likely meningitidis -adults/adolescents: autoinnoculation from infected genitalia What can cause Hyperacute conjunctivitis? - ANSWER Self inoculation, from infected genitalia Most commonly caused by Neisseria gonorrhoeae, less commonly caused by Neisseria meningitidis. Is Hyperacute conjunctivitis a severe sight-threatening ocular infection? - ANSWER yes What are the Common agents that cause Acute bacterial conjunctivitis In children? - ANSWER Moraxella catarrhalis is also common Which of the following conditions is the clinical name for "farsightedness"? A. Hyperopia B. Myopia C. Presbyopia D. Strabismus E. Ptosis - ANSWER A. Hyperopia What viruses can cause Viral conjunctivitis? - ANSWER Adenoviruses, herpesviruses, enteroviruses, What are the Common agents that cause Acute bacterial conjunctivitis In adults? - ANSWER Streptocococus pneumoniae, S. aureus, Haemophilus influenzae in adults What can cause corneal trauma? - ANSWER Prolonged wearing contact lenses, sudden rise in pressure Define hypercapnia - ANSWER excessive carbon dioxide in the bloodstream, typically caused by inadequate respiration. How does Opiate usage affect the pupillary reflex? - ANSWER Opiate usage will result in dilated pupils that are unresponsive to light Define Glaucoma - ANSWER An optic neuropathy characterized by optic disk cupping and visual field loss. Hyperopia or farsightedness - ANSWER a condition in which the optic axis is too short and accommodation cannot make the lens thick enough to focus light from a nearby object on the retina, so the light comes to a focus behind the retina, and the image on the retina is blurry; the person can see distant objects clearly but not nearby objects myopia or nearsightedness - ANSWER a condition in which the optic axis is too long and accommodation cannot make the lens thin enough to focus light from a distant object on the retina, so the light comes to a focus in front of the retina, and the image on the retina is blurry; the person can see nearby objects clearly but not distant objects Know spontaneous vs traumatic pneumothorax - ANSWER spontaneous pneumothorax - ANSWER occurs when an air-filled blister on the lung surface ruptures traumatic pneumothorax - ANSWER caused by penetrating or non-penetrating injuries What are some of the causes of cataract? - ANSWER Aging, genetic influences, environmental and metabolic influences, drugs, injury, diabetes, long term exposure to sunlight, heavy smoking, trauma/disease, developmental defect What is hypoxemia? - ANSWER It refers to a reduction in the PO2 of the arterial blood; specifically PO2 less than 60 mm Hg. What causes hypoxemia? - ANSWER Hypoxemia can be caused by an inadequate amount of O2 in the air, diseases of the respiratory system, dysfunction of neurologic systems or alterations in circulatory function. What is cyanosis? - ANSWER Cyanosis refer to a bluish discoloration of skin and mucous membranes from excess deoxygenated hemoglobin in small blood vessels. Which of the following best describes Glaucoma? a. it is a lens opacity that interferes with the transmission of light to the retina b. An optic neuropathy characterized by optic disk cupping and visual field loss. c. it refers to the inflammation of the cornea d. it is the inflammation of the conjunctiva - ANSWER b. An optic neuropathy characterized by optic disk cupping and visual field loss. True or False: Both hypercapnia and hypoxemia will lead to respiratory failure if untreated - ANSWER True. In both hypercapnia (PCO2 50 mm Hg) tissues accumulate carbon dioxide; in hypoxemia (PO2 60 mm Hg) less oxygen is delivered to the tissues. In both cases, gas exchange is impaired, and respiratory will failure will result unless the conditions are corrected (with oxygen, mechanical ventilation, etc.). Define COPD - ANSWER COPDs are characterized by progressive airflow limitations that are not fully reversible. COPDs are linked to cigarette smoking. There is a gradual onset with slowly progressive symptoms of dyspnea (labored breathing), and shortness of breath. What causes hypercapnia? - ANSWER Hypercapnia can occur in a number of disorders that cause hypoventilation or mismatching of ventilation and perfusion Define atelectasis - ANSWER Refers to a partial collapsed lung or inadequate inflation of a portion of the lung or alveoli complex What are the two types of atelectasis & what are they? - ANSWER primary is present at birth and secondary develops during neonatal period or later What are the some of the risk factors? - ANSWER prolonged immobility, underlying lung disease, fractured ribs, etc. Define Pleural Effusion. What causes it? What are some risk factors? - ANSWER Collection of excess fluid in the pleural space -develops when there is an increased production or decreased drainage of pleural fluid Risk factors: thoracic/abdominal surgery, inflammation in lungs, blockage of lymphatic drainage Define pneumothorax. What can cause it? - ANSWER Air enters the pleural cavity, restricting lung expansion Spontaneous: air-filled blister on the lung ruptures Traumatic: air enters through chest injuries -Tension: air enters pleural cavity through wound on inhalation, cannot leave on exhalation -Open: air enters pleural cavity through the wound on inhalation and leaves on exhalation True or False: open pneumothorax is more life-threatening than tension pneumothorax - ANSWER False. In open pneumothorax, inhaled air compresses the affected side's lung, but during exhalation, the lung reinflates somewhat.In tension pneumothorax, a sort of one-way valve exists— the air enters the affected side during inhalation, but is unable to leave when the patient exhales. Therefore, all of this air exerts increased pressure on the organs of the thoracic cage. Unless the pressure is relieved, tension pneumothorax is fatal. KNOW PINK PUFFERS - ANSWER Breathing fast, using accessory muscles, pursed lip breathing Labored breathing Increased respiration to maintain oxygen levels USUALLY EMPHYSEMA Define asthma What are the 2 major types? - ANSWER Chronic inflammatory disorder of airways, reversible airway obstruction -Allergic asthma: allergen causes type 1 hypersensitivity response In what range will a COPD client's blood pH fall? - ANSWER In COPD, the blood is more acidic as the pH levels are low. What is the primary cause of emphysema? - ANSWER cigarette smoking How does the alveoli get destroyed? - ANSWER Inhaled irritants increase the number of neutrophils. Neutrophils in the alveoli secrete trypsin. Trypsin damages the aveoli.

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NU606/ NU 606 EXAM 2 (2025-
2026) ADVANCED
PATHOPHYSIOLOGY GUIDE 90+
QUESTIONS WITH CORRECT
VERIFIED ANSWERS ||
GUARANTEED PASS || NEWEST
VERSION

What are opportunistic pathogens? - ANSWER Only
affects you when your immune system is trash, e.g those
with HIV/AIDs (Usually die of secondary infection)

What are prions? - ANSWER No genome, proteins
Can cause disease
Can also cause normal proteins to change shape and
become new prions (if ingested)
*Mad cow disease

What are prion-associated diseases - ANSWER 1.
Creutzfeldt-Jacob Disease
2. Variant Creutzfeldt-Jacob Disease
3. Bovine Spongiform Encephalopathy (BSE, Mad Cow
Disease)
4. Kuru
- All of them cause the brain to look like a sponge
- ALL cause cognitive impairment

, How are viruses different than bacteria? - ANSWER -
Some have envelopes, if they don't they're considered
naked
- Submicroscopic infectious agents that have either DNA
or RNA
- Capsid protects virus when it is NOT inside host cell
(i.e. Hanging onto the door knob)

What is bacteria? - ANSWER Prokaryote
-W/o nuclei and no membrane-bound organelles
-Produce biofilm: Collection of bacteria on surface
-Contain RNA and DNA
-Bacteria with plasmids can give an "edge"; codes for
resistance to certain antibiotics
- Use hosts for food and shelter

Are most fungal infections on the surface of the body? -
ANSWER Yes

What are fomites? - ANSWER inanimate objects that
can spread disease such as a doorknob, clothing,
countertop etc

What are zoonoses - ANSWER diseaes of animals that
can spread to humans

How do pathogenic microbes get into the body? -
ANSWER Depends on the microbe, but in general, they
can be ingested, inhaled or get in through vaginal fluid or
semen.

What are virulence factors?

,How do they allow bacteria to be pathogenic? -
ANSWER Allow bacteria to be pathogenic
- Destroy some part of the host, making it easier to get in
or replicate
i.e. Lipase - digest oil on skin

Where do bacteria endotoxins come from?
What do they cause? - ANSWER Endotoxins cause host
immunize reactions

What are bacterial exotoxins?
What do they do to host cells? - ANSWER - Proteins
released by bacteria
- Damage or kill host cells

What is sepsis? - ANSWER toxic inflammatory
condition arising from the spread of microbes, especially
bacteria or their toxins, from a focus of infection in the
blood

If a word ends in itis, what does that mean? - ANSWER
Inflammation, may or may not be due to infection

What are the major mechanisms in which antibiotics
inhibit or kill bacteria? - ANSWER - Cell wall synthesis
- Protein Synthesis
- Nucleic acid synthesis
- Metabolism

How do bacteria fight back? - ANSWER - Break down
antibiotics
- Altering antibiotic binding sites
- Using different metabolic pathways

, - Changing cell walls to keep antibiotics out

How do antivirals work? - ANSWER Inhibit
-Viral RNA and DNA synthesis
-Viral enzymes
-Viral binding to cells
- Production of capsids of new viruses

Bacterial endotoxins come from_______________.
A. The lipids from the outer membrane of a Gram
negative bacterial cell wall
B. Proteins from Gram positive bacteria
C. Viruses
D. None of the above - ANSWER A. The lipids from the
outer membrane of a Gram negative bacterial cell wall.

True or False: All interactions between humans and
microorganisms are detrimental. - ANSWER False, some
microorganisms perform important functions for their
human hosts, like producing vitamins, assisting
digestion, or preventing harmful pathogens from entering
host.

Which pathogen is an intracellular parasite consisting of
a protein coat surrounding a nucleic acid?
A. Prion
B. Virus
C. Bacteria
D. Protozoa - ANSWER B. Virus

True or False: Certain bacterial cells release proteins
called endotoxins during growth. - ANSWER False;
endotoxins are proteins; endotoxins contain no protein

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