2026) ADVANCED
PATHOPHYSIOLOGY GUIDE 90+
QUESTIONS WITH CORRECT
VERIFIED ANSWERS ||
GUARANTEED PASS || NEWEST
VERSION
What are opportunistic pathogens? - ANSWER Only
affects you when your immune system is trash, e.g those
with HIV/AIDs (Usually die of secondary infection)
What are prions? - ANSWER No genome, proteins
Can cause disease
Can also cause normal proteins to change shape and
become new prions (if ingested)
*Mad cow disease
What are prion-associated diseases - ANSWER 1.
Creutzfeldt-Jacob Disease
2. Variant Creutzfeldt-Jacob Disease
3. Bovine Spongiform Encephalopathy (BSE, Mad Cow
Disease)
4. Kuru
- All of them cause the brain to look like a sponge
- ALL cause cognitive impairment
, How are viruses different than bacteria? - ANSWER -
Some have envelopes, if they don't they're considered
naked
- Submicroscopic infectious agents that have either DNA
or RNA
- Capsid protects virus when it is NOT inside host cell
(i.e. Hanging onto the door knob)
What is bacteria? - ANSWER Prokaryote
-W/o nuclei and no membrane-bound organelles
-Produce biofilm: Collection of bacteria on surface
-Contain RNA and DNA
-Bacteria with plasmids can give an "edge"; codes for
resistance to certain antibiotics
- Use hosts for food and shelter
Are most fungal infections on the surface of the body? -
ANSWER Yes
What are fomites? - ANSWER inanimate objects that
can spread disease such as a doorknob, clothing,
countertop etc
What are zoonoses - ANSWER diseaes of animals that
can spread to humans
How do pathogenic microbes get into the body? -
ANSWER Depends on the microbe, but in general, they
can be ingested, inhaled or get in through vaginal fluid or
semen.
What are virulence factors?
,How do they allow bacteria to be pathogenic? -
ANSWER Allow bacteria to be pathogenic
- Destroy some part of the host, making it easier to get in
or replicate
i.e. Lipase - digest oil on skin
Where do bacteria endotoxins come from?
What do they cause? - ANSWER Endotoxins cause host
immunize reactions
What are bacterial exotoxins?
What do they do to host cells? - ANSWER - Proteins
released by bacteria
- Damage or kill host cells
What is sepsis? - ANSWER toxic inflammatory
condition arising from the spread of microbes, especially
bacteria or their toxins, from a focus of infection in the
blood
If a word ends in itis, what does that mean? - ANSWER
Inflammation, may or may not be due to infection
What are the major mechanisms in which antibiotics
inhibit or kill bacteria? - ANSWER - Cell wall synthesis
- Protein Synthesis
- Nucleic acid synthesis
- Metabolism
How do bacteria fight back? - ANSWER - Break down
antibiotics
- Altering antibiotic binding sites
- Using different metabolic pathways
, - Changing cell walls to keep antibiotics out
How do antivirals work? - ANSWER Inhibit
-Viral RNA and DNA synthesis
-Viral enzymes
-Viral binding to cells
- Production of capsids of new viruses
Bacterial endotoxins come from_______________.
A. The lipids from the outer membrane of a Gram
negative bacterial cell wall
B. Proteins from Gram positive bacteria
C. Viruses
D. None of the above - ANSWER A. The lipids from the
outer membrane of a Gram negative bacterial cell wall.
True or False: All interactions between humans and
microorganisms are detrimental. - ANSWER False, some
microorganisms perform important functions for their
human hosts, like producing vitamins, assisting
digestion, or preventing harmful pathogens from entering
host.
Which pathogen is an intracellular parasite consisting of
a protein coat surrounding a nucleic acid?
A. Prion
B. Virus
C. Bacteria
D. Protozoa - ANSWER B. Virus
True or False: Certain bacterial cells release proteins
called endotoxins during growth. - ANSWER False;
endotoxins are proteins; endotoxins contain no protein