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NURS 167 2025 ACTUAL EXAM 400 QUESTIONS AND CORRECT
DETAILED ANSWERS|ALREADY GRADED A+, EXAMS OF NURSING
If fertilization of an ovum does not occur during a menstrual cycle, which of the following
structures responds to the increased levels of estrogen and progesterone?
1 Ovary
2 Hypothalamus
3 Pituitary gland
4 Corpus luteum - ANSWER-3. Pituitary gland
If fertilization does not occur, the pituitary responds to the increased levels of estrogen and
progesterone by shutting off the release of follicle-stimulating hormone and luteinizing
hormone. The ovaries, hypothalamus, and corpus luteum are not directly involved.
What is an adverse effect associated with estrogen therapy?
1. Nausea
2. Dry Skin
3. Weight loss
4. Higher-pitched voice - ANSWER-1. Nausea
The most common undesirable effect of estrogen use is nausea. Photosensitivity may also occur
with estrogen therapy. One common dermatologic effect of note is chloasma, not dry skin.
Weight loss and a higher-pitched voice are not caused by estrogen therapy.
Which patient statement indicates to the nurse full patient understanding of the discharge
instructions regarding alendronate?
1. "I need to decrease my intake of dairy products to prevent hypercalcemia."
2. "I need to take this medication with food to prevent damage to my esophagus."
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3. "This medication will help relieve the bone pain I have from my osteoporosis."
4. "I will take the medication on an empty stomach and not lie down for 30 minutes." -
ANSWER-4. "I will take the medication on an empty stomach and not lie down for 30 minutes."
Alendronate can cause erosive esophagitis. To prevent this side effect, it is important to take the
medication first thing in the morning on an empty stomach without any other medications and
to maintain an upright position for 30 minutes. These actions facilitate rapid absorption and
prevent reflux into the esophagus. Decreasing dairy intake is not indicated. The medication does
not directly relieve bone pain caused by osteoporosis.
Which statement indicates that the patient understands the benefit of continuous
administration of progestin with an estrogen regimen?
1. "Endometrial cancer risk can be reduced by adding progestin."
2. "The progestin in the regimen will help prevent breast cancer."
3. "The progestin in the regimen will help prevent ovarian cancer."
4. "Vaginal cancer is prevented by adding progestin to the regimen." - ANSWER-1. "Endometrial
cancer risk can be reduced by adding progestin."
Estrogen, given alone, has been associated with an increased risk of endometrial hyperplasia,
which can lead to endometrial cancer. Progestin reduces the incidence of endometrial
hyperplasia.
The nurse is teaching a group of students about the use of megestrol. Which statement by a
student suggests the need for additional teaching?
1. "It is used for breast cancer."
2. "It is used for endometrial cancer."
3. "It is used for the prevention of pregnancy."
4. "It is used for cachexia of AIDS." - ANSWER-3. "It is used for the prevention of pregnancy."
,3|Page
Megestrol is not used for prevention of pregnancy. It is a synthetic progestin that is structurally
very similar to progesterone. Although megestrol shares the actions of the progestins, it is
primarily used in the palliative management of recurrent, inoperable, or metastatic endometrial
or breast cancer. Because it can cause appetite stimulation and weight gain, it is also used in the
management of anorexia, cachexia, or unexplained substantial weight loss in patients with AIDS
and in patients with cancer.
Which adverse reaction may occur as a result of raloxifene use during perimenopause?
1. Hot flashes
2. Loss of hair
3. Brown discoloration of face
4. Yellow undertone to the skin - ANSWER-1. Hot flashes
Raloxifene is a selective estrogen receptor modulator (SERM) used in the treatment of
osteoporosis. An adverse reaction associated with this medication, especially during
perimenopause, is hot flashes. Although hair loss and chloasma may occur with other estrogen
therapies, these are not adverse reactions associated with this specific medication. Progestin
therapy can cause liver dysfunction and jaundice, which is a yellowing of the skin and the sclera
of the eyes.
STUDY TIP: A word of warning: do not expect to achieve the maximum benefits of this review
tool by cramming a few days before the examination. It doesn't work! Instead, organize planned
study sessions in an environment that you find relaxing, free of stress, and supportive of the
learning process.
A patient with which condition should not use oral contraceptives as a method of birth control?
1. Renal failure
2. Ovarian failure
3. Pulmonary embolism
4. Abnormal vaginal bleeding - ANSWER-3. Pulmonary embolism
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A history of pulmonary embolism increases the patient's risk for developing thromboembolism,
so this patient should not use oral contraceptives. Renal failure, ovarian failure, and abnormal
vaginal bleeding are not contraindications for the use of oral contraceptives. Denosumab is
contraindicated in patients who have renal failure. Fertility medications, such as clomiphene,
are contraindicated in patients who have ovarian failure. Estrogen therapy is contraindicated in
patients who have abnormal vaginal bleeding.
The nurse is assessing a patient who is prescribed estrogen replacement therapy. A history of
which medical condition would be a contraindication to this therapy?
1. Weight loss
2. Dysmenorrhea
3. Uterine bleeding
4. DVT - ANSWER-4. DVT
The most serious adverse effects of the estrogens are thromboembolic events. A previous
history would put the patient at increased risk. Uterine bleeding is an indication for estrogen
therapy. A history of weight loss or dysmenorrhea would not be a contraindication for estrogen
replacement therapy.
The nurse is teaching students about applying a transdermal estradiol patch. Which statement
made by a student suggests effective learning?
1. "Rotate the patch every 2 weeks."
2. "Rotate the patch at the same time each day."
3. "Apply the patch to the breast area for better absorption."
4. "Apply the patch to the lower abdomen for better absorption." - ANSWER-4. "Apply the patch
to the lower abdomen for better absorption."
The estradiol transdermal patch should be applied as prescribed, which is usually one patch
applied once or twice weekly to the lower abdomen and not to the breast or chest areas. The
NURS 167 2025 ACTUAL EXAM 400 QUESTIONS AND CORRECT
DETAILED ANSWERS|ALREADY GRADED A+, EXAMS OF NURSING
If fertilization of an ovum does not occur during a menstrual cycle, which of the following
structures responds to the increased levels of estrogen and progesterone?
1 Ovary
2 Hypothalamus
3 Pituitary gland
4 Corpus luteum - ANSWER-3. Pituitary gland
If fertilization does not occur, the pituitary responds to the increased levels of estrogen and
progesterone by shutting off the release of follicle-stimulating hormone and luteinizing
hormone. The ovaries, hypothalamus, and corpus luteum are not directly involved.
What is an adverse effect associated with estrogen therapy?
1. Nausea
2. Dry Skin
3. Weight loss
4. Higher-pitched voice - ANSWER-1. Nausea
The most common undesirable effect of estrogen use is nausea. Photosensitivity may also occur
with estrogen therapy. One common dermatologic effect of note is chloasma, not dry skin.
Weight loss and a higher-pitched voice are not caused by estrogen therapy.
Which patient statement indicates to the nurse full patient understanding of the discharge
instructions regarding alendronate?
1. "I need to decrease my intake of dairy products to prevent hypercalcemia."
2. "I need to take this medication with food to prevent damage to my esophagus."
,2|Page
3. "This medication will help relieve the bone pain I have from my osteoporosis."
4. "I will take the medication on an empty stomach and not lie down for 30 minutes." -
ANSWER-4. "I will take the medication on an empty stomach and not lie down for 30 minutes."
Alendronate can cause erosive esophagitis. To prevent this side effect, it is important to take the
medication first thing in the morning on an empty stomach without any other medications and
to maintain an upright position for 30 minutes. These actions facilitate rapid absorption and
prevent reflux into the esophagus. Decreasing dairy intake is not indicated. The medication does
not directly relieve bone pain caused by osteoporosis.
Which statement indicates that the patient understands the benefit of continuous
administration of progestin with an estrogen regimen?
1. "Endometrial cancer risk can be reduced by adding progestin."
2. "The progestin in the regimen will help prevent breast cancer."
3. "The progestin in the regimen will help prevent ovarian cancer."
4. "Vaginal cancer is prevented by adding progestin to the regimen." - ANSWER-1. "Endometrial
cancer risk can be reduced by adding progestin."
Estrogen, given alone, has been associated with an increased risk of endometrial hyperplasia,
which can lead to endometrial cancer. Progestin reduces the incidence of endometrial
hyperplasia.
The nurse is teaching a group of students about the use of megestrol. Which statement by a
student suggests the need for additional teaching?
1. "It is used for breast cancer."
2. "It is used for endometrial cancer."
3. "It is used for the prevention of pregnancy."
4. "It is used for cachexia of AIDS." - ANSWER-3. "It is used for the prevention of pregnancy."
,3|Page
Megestrol is not used for prevention of pregnancy. It is a synthetic progestin that is structurally
very similar to progesterone. Although megestrol shares the actions of the progestins, it is
primarily used in the palliative management of recurrent, inoperable, or metastatic endometrial
or breast cancer. Because it can cause appetite stimulation and weight gain, it is also used in the
management of anorexia, cachexia, or unexplained substantial weight loss in patients with AIDS
and in patients with cancer.
Which adverse reaction may occur as a result of raloxifene use during perimenopause?
1. Hot flashes
2. Loss of hair
3. Brown discoloration of face
4. Yellow undertone to the skin - ANSWER-1. Hot flashes
Raloxifene is a selective estrogen receptor modulator (SERM) used in the treatment of
osteoporosis. An adverse reaction associated with this medication, especially during
perimenopause, is hot flashes. Although hair loss and chloasma may occur with other estrogen
therapies, these are not adverse reactions associated with this specific medication. Progestin
therapy can cause liver dysfunction and jaundice, which is a yellowing of the skin and the sclera
of the eyes.
STUDY TIP: A word of warning: do not expect to achieve the maximum benefits of this review
tool by cramming a few days before the examination. It doesn't work! Instead, organize planned
study sessions in an environment that you find relaxing, free of stress, and supportive of the
learning process.
A patient with which condition should not use oral contraceptives as a method of birth control?
1. Renal failure
2. Ovarian failure
3. Pulmonary embolism
4. Abnormal vaginal bleeding - ANSWER-3. Pulmonary embolism
, 4|Page
A history of pulmonary embolism increases the patient's risk for developing thromboembolism,
so this patient should not use oral contraceptives. Renal failure, ovarian failure, and abnormal
vaginal bleeding are not contraindications for the use of oral contraceptives. Denosumab is
contraindicated in patients who have renal failure. Fertility medications, such as clomiphene,
are contraindicated in patients who have ovarian failure. Estrogen therapy is contraindicated in
patients who have abnormal vaginal bleeding.
The nurse is assessing a patient who is prescribed estrogen replacement therapy. A history of
which medical condition would be a contraindication to this therapy?
1. Weight loss
2. Dysmenorrhea
3. Uterine bleeding
4. DVT - ANSWER-4. DVT
The most serious adverse effects of the estrogens are thromboembolic events. A previous
history would put the patient at increased risk. Uterine bleeding is an indication for estrogen
therapy. A history of weight loss or dysmenorrhea would not be a contraindication for estrogen
replacement therapy.
The nurse is teaching students about applying a transdermal estradiol patch. Which statement
made by a student suggests effective learning?
1. "Rotate the patch every 2 weeks."
2. "Rotate the patch at the same time each day."
3. "Apply the patch to the breast area for better absorption."
4. "Apply the patch to the lower abdomen for better absorption." - ANSWER-4. "Apply the patch
to the lower abdomen for better absorption."
The estradiol transdermal patch should be applied as prescribed, which is usually one patch
applied once or twice weekly to the lower abdomen and not to the breast or chest areas. The
