Menopause Practice Questions with Multiple
choice Answers
The most effective treatment to alleviate postmenopausal vasomotor symptoms (hot flashes and
night sweats) is:
A. Estrogen therapy
B. Selective estrogen-receptor modulators (SERMs)
C. Testosterone therapy
D. Clonidine
A.
Which of the following CYP450 isoenzymes metabolizes both estrogen and medroxyprogesterone?
A. 3A4
B. 1A2
C. 2D6
D. All of the above
A.
Continued vasomotor symptoms in a 52-year-old postmenopausal woman with a history of
hysterectomy receiving 0.3 mg of oral conjugated equine estrogens can best be managed by:
A. Changing to a SERM
B. Changing to gabapentin
C. Increasing the daily estrogen dose
D. Decreasing the daily estrogen dose
C.
, A 54-year-old postmenopausal woman is complaining of vaginal dryness, itching, and pain with
intercourse. She has not had any other problems associated with menopause and has an intact
uterus. Which of the following recommendations is the best treatment option that balances risks
and benefits for the management of this patient's symptoms?
A. Oral conjugated estrogen + medroxyprogesterone acetate
B. Transdermal estradiol + micronized oral progesterone
C. Intravaginal estrogen cream + oral progestogen
D. Intravaginal estrogen cream
D.
Conjugated equine estrogen therapy alone has demonstrated to significantly increase the risk of:
A. Coronary heart disease
B. Stroke
C. Colorectal cancer
D. Breast cancer
B.
Which of the following agents would be the best option to treat moderate hot flashes in a 55-year-
old woman with history of breast cancer?
A. Tibolone
B. Estrogen
C. Paroxetine
D. Progestogen
C.
choice Answers
The most effective treatment to alleviate postmenopausal vasomotor symptoms (hot flashes and
night sweats) is:
A. Estrogen therapy
B. Selective estrogen-receptor modulators (SERMs)
C. Testosterone therapy
D. Clonidine
A.
Which of the following CYP450 isoenzymes metabolizes both estrogen and medroxyprogesterone?
A. 3A4
B. 1A2
C. 2D6
D. All of the above
A.
Continued vasomotor symptoms in a 52-year-old postmenopausal woman with a history of
hysterectomy receiving 0.3 mg of oral conjugated equine estrogens can best be managed by:
A. Changing to a SERM
B. Changing to gabapentin
C. Increasing the daily estrogen dose
D. Decreasing the daily estrogen dose
C.
, A 54-year-old postmenopausal woman is complaining of vaginal dryness, itching, and pain with
intercourse. She has not had any other problems associated with menopause and has an intact
uterus. Which of the following recommendations is the best treatment option that balances risks
and benefits for the management of this patient's symptoms?
A. Oral conjugated estrogen + medroxyprogesterone acetate
B. Transdermal estradiol + micronized oral progesterone
C. Intravaginal estrogen cream + oral progestogen
D. Intravaginal estrogen cream
D.
Conjugated equine estrogen therapy alone has demonstrated to significantly increase the risk of:
A. Coronary heart disease
B. Stroke
C. Colorectal cancer
D. Breast cancer
B.
Which of the following agents would be the best option to treat moderate hot flashes in a 55-year-
old woman with history of breast cancer?
A. Tibolone
B. Estrogen
C. Paroxetine
D. Progestogen
C.